Valérie Hox
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Sinusitis and nasal conditions
- Nasal Surgery and Airway Studies
- Respiratory and Cough-Related Research
- Food Allergy and Anaphylaxis Research
- Adolescent and Pediatric Healthcare
- Olfactory and Sensory Function Studies
- Occupational exposure and asthma
- Neonatal Respiratory Health Research
- Head and Neck Surgical Oncology
- Eosinophilic Esophagitis
- Pediatric health and respiratory diseases
- Ocular Surface and Contact Lens
- Childhood Cancer Survivors' Quality of Life
- Ion Channels and Receptors
- Contact Dermatitis and Allergies
- Immune Response and Inflammation
- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Reproductive System and Pregnancy
- Mast cells and histamine
- Obstructive Sleep Apnea Research
- Otitis Media and Relapsing Polychondritis
- Inhalation and Respiratory Drug Delivery
Cliniques Universitaires Saint-Luc
2017-2025
UCLouvain
2020-2025
KU Leuven
2010-2024
Hôpital Saint-Luc
2020
Macquarie University
2019
University of Zagreb
2018
Odense University Hospital
2017
National Institutes of Health
2014-2016
National Institute of Allergy and Infectious Diseases
2014-2016
Abstract Nasal allergen challenge (NAC) is an important tool to diagnose allergic rhinitis. In daily clinical routine, experimentally, or when measuring therapeutic success clinically, nasal fundamental. It further one of the key diagnostic tools initiating specific immunotherapy. So far, national recommendations offered guidance on its execution; however, international divergence left many questions unanswered. These differences in literature caused EAACI initiate a task force answer unmet...
Chronic rhinosinusitis (CRS) is a common yet under-recognised chronic inflammatory disease of the nose and paranasal sinuses that classified according to presence (CRSwNP) or absence (CRSsNP) nasal polyps.This paper reports methodology descriptive results Global Allergy Asthma European Network (GALEN) cohort. We established large CRS cohort within GALEN consortium (European FP6 research initiative) identify endotypes, natural course, its impact on health-related quality life (HRQoL)....
Nasal endoscopy is not only used for the diagnosis of chronic rhinosinusitis with nasal polyps (CRSwNP), but also monitoring response to therapy playing an important role in both daily practice and research. In contrast patient-reported outcomes, endoscopic polyp scoring by independent blinded readers objective measurement, influenced placebo effect. It safer cheaper compared computed tomography imaging therefore, better suited regular assessments extent disease. Since early 90s, a variety...
Severe chronic rhinosinusitis with nasal polyps (CRSwNP), a form of diffuse bilateral (usually type 2) CRS, is debilitating disease significant impact on quality life (QoL). With novel knowledge and treatment options becoming available, there growing need to update or revise key definitions enable communication across different specialties dealing agree goals care in CRSwNP. The European Forum for Research Education Allergy Airway diseases (EUFOREA) EPOS expert members discussed how measure...
Abstract In less than half a century, allergy, originally perceived as rare disease, has become major public health threat, today affecting the lives of more 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting budgets systems. More disturbingly, its prevalence impact are on rise, development that been associated with environmental lifestyle changes accompanying continuous process urbanization globalization. Therefore, there is an urgent need...
Abstract Adolescent and young adult (AYA) patients need additional support, while they experience the challenges associated with their age. They specific training to learn knowledge skills required confidently self‐manage allergies and/or asthma. Transitional care is a complex process, which should address psychological, medical, educational vocational needs of AYA in developmentally appropriate way. The European Academy Allergy Clinical Immunology has developed clinical practice guideline...
The coronavirus disease 2019 (COVID-19) has evolved into a pandemic infectious transmitted by the severe acute respiratory syndrome (SARS-CoV-2). Allergists and other healthcare providers (HCPs) in field of allergies associated airway diseases are on front line, taking care patients potentially infected with SARS-CoV-2. Hence, strategies practices to minimize risks infection for both HCPs treated have be developed followed allergy clinics.The scientific information COVID-19 was analysed...
The GALEN rhinosinusitis cohort: chronic with nasal
Airway hyperreactivity (AHR) is a key feature of bronchial asthma, and inhalation irritants may facilitate development nonallergic AHR. Swimmers exposed to hypochlorite (ClO(-))-containing water show higher risk developing We developed mouse model in which instillation ClO(-) before ovalbumin (OVA) induces AHR without inflammatory cells.To investigate the mechanisms ClO(-)-OVA-induced AHR.The involvement transient receptor potential ankyrin (TRPA)1 channel was checked vivo by use TRPA1(-/-)...
Abstract Background Chronic rhinosinusitis is regarded as a chronic airway disease. According to WHO recommendations, it may be risk factor for COVID‐19 patients. In most CRSwNP cases, the inflammatory changes affecting nasal and paranasal mucous membranes are type‐2 (T2) inflammation endotypes. Methods The current knowledge on treatment options CRS was analyzed by literature search in Medline, Pubmed, international guidelines, Cochrane Library Internet. Results Based literature,...
Abstract Background Chronic rhinosinusitis (CRS) is a chronic inflammatory disease associated with substantial personal and socioeconomic burden. Monitoring of patient‐reported outcomes by mobile technology offers the possibility to better understand real‐life burden CRS. Methods This study reports on cross‐sectional evaluation data 626 users mySinusitisCoach (mSC), application for CRS patients. Patient characteristics mSC were analysed as well level control based VAS global symptom score...
On March 11th 2020, the World Health Organization (WHO) declared COVID-19 pandemic, with subsequent profound impact on entire health care system.During outbreak, activities in rhinology outpatient clinic and operation rooms are limited to emergency only.Health practitioners faced need perform rhinological skull base procedures patients a positive or unknown status.This article aims provide recommendations relevant information for rhinologists, based amount of (anecdotal) data, guarantee...
Chronic rhinosinusitis with nasal polyposis (NP) represents an invalidating disorder that causes mainly blockage and loss of smell. The aim this study is to investigate correlations between individual subjective objective parameters stable NP disease.65 patients scored their sinonasal symptoms on a visual analogue scale (VAS) questionnaires (SNOT-22 SF-36). Peak inspiratory flow (PNIF) measurement, Sniffinatm Sticks (SS) smell test, blood analysis for eosinophilia, total IgE culture...