A5073553159- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Visual perception and processing mechanisms
- Dermatology and Skin Diseases
- Ophthalmology and Visual Impairment Studies
- Contact Dermatitis and Allergies
- Global Health Care Issues
- Eosinophilic Esophagitis
- Transgenic Plants and Applications
- Thermoregulation and physiological responses
- Neurobiology and Insect Physiology Research
- Neural dynamics and brain function
- Glaucoma and retinal disorders
- Health disparities and outcomes
- Synthetic Aperture Radar (SAR) Applications and Techniques
- Climate Change Communication and Perception
- Health, Environment, Cognitive Aging
- Plant responses to elevated CO2
- Multisensory perception and integration
- Pediatric health and respiratory diseases
- Birth, Development, and Health
- Climate Change and Geoengineering
Harvard University
2023-2025
Public Health Department
2025
Stanford University
2016-2024
Parker Hannifin (United States)
2019-2024
Universities of Giessen and Marburg Lung Center
2023
Advanced Engineering (Czechia)
2023
Pulmonary and Allergy Associates
2019
Stanford Medicine
2019
Institute of Infection and Immunity
2018
University of California, San Diego
2008-2011
BACKGROUND. IL-33, found in high levels participants with allergic disorders, is thought to mediate reactions. Etokimab, an anti–IL-33 biologic, has previously demonstrated a good safety profile and favorable pharmacodynamic properties many clinical studies.
Climate change is not just jeopardizing the health of our planet, but it increasingly impacting immune health.There an expanding body evidence that climaterelated exposures, such as air pollution, heat, wildfires, extreme weather events, and biodiversity loss significantly disrupt functioning human system.These exposures manifest in a broad range stimuli including antigens, allergens, heat stress, pollutants, microbiota changes, other toxic substances.Such pose direct indirect threat to...
Global warming and climate change have increased the pollen burden frequency intensity of wildfires, sand dust storms, thunderstorms, heatwaves—with concomitant increases in air pollution, heat stress, flooding. These environmental stressors alter human exposome trigger complex immune responses. In parallel, pollutants, allergens, other factors increase risks skin mucosal barrier disruption microbial dysbiosis, while a loss biodiversity reduced exposure to diversity impairs tolerogenic...
The coronavirus disease 2019 (COVID-19) has evolved into a pandemic infectious transmitted by the severe acute respiratory syndrome (SARS-CoV-2). Allergists and other healthcare providers (HCPs) in field of allergies associated airway diseases are on front line, taking care patients potentially infected with SARS-CoV-2. Hence, strategies practices to minimize risks infection for both HCPs treated have be developed followed allergy clinics.The scientific information COVID-19 was analysed...
The rising prevalence of many chronic diseases related to gut barrier dysfunction coincides with the increased global usage dietary emulsifiers in recent decades. We therefore investigated effect frequently used food on cytotoxicity, function, transcriptome alterations, and protein expression gastrointestinal epithelial cells.Human intestinal organoids originating from induced pluripotent stem cells, colon organoid organ-on-a-chip, liquid-liquid interface cells were cultured presence two...
IgE-mediated food allergy (IgE-FA) occurs due to a breakdown in immune tolerance that leads detrimental type 2 helper T cell (TH2) adaptive response. While the processes governing this loss of are incompletely understood, several host-related and environmental factors impacting risk IgE-FA development have been identified. Mounting evidence supports role an impaired epithelial barrier IgE-FA, with exposure allergens through damaged skin gut epithelium leading aberrant production alarmins...
Abstract Pollen and molds are environmental allergens that affected by climate change. As pollen exhibit geographical variations, we sought to understand the impact of change (temperature, carbon dioxide (CO 2 ), precipitation, smoke exposure) on common in San Francisco Bay Area, one largest urban areas United States. When using time-series regression models between 2002 2019, annual average number weeks with concentrations higher than zero increased over time. For tree pollens, increase...
Abstract Background Oral immunotherapy (OIT) is frequently discontinued due to adverse events (AEs) and current data suggests that lowering OIT doses can minimize severity frequency of AEs. However, the minimum daily dose enable desensitization induce immune responses in multi‐food (mOIT) unknown. Methods Participants aged 2–25 years with allergies were pretreated fixed‐dose omalizumab (150 mg, 3 doses, every 4 weeks), randomized 1:1 receive mOIT a total maintenance either 300 or 1200 mg...
The incidence and prevalence of food allergy (FA) is increasing. While several studies have established the safety efficacy early introduction single allergens in infants for prevention FA, exact dose, frequency, number that can be safely introduced to infants, particularly those at high or low risk atopy, are still unclear. This 1-year pilot study evaluated foods (milk, egg, peanut) vs. two (milk/egg, egg/peanut, milk/peanut) multiple...