A5080129663- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Lichen and fungal ecology
- Dermatology and Skin Diseases
- Indoor Air Quality and Microbial Exposure
- Respiratory viral infections research
- Olfactory and Sensory Function Studies
- Contact Dermatitis and Allergies
- Air Quality and Health Impacts
- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
- Ecology and Conservation Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pneumonia and Respiratory Infections
- Plant and animal studies
- Climate Change and Health Impacts
- Software System Performance and Reliability
- Cloud Computing and Resource Management
- Advanced Data Storage Technologies
- Service-Oriented Architecture and Web Services
- Urticaria and Related Conditions
- Web Data Mining and Analysis
- COVID-19 epidemiological studies
- Inhalation and Respiratory Drug Delivery
Hanyang University
2016-2025
Hanyang University Guri Hospital
2014-2024
Hanyang University Medical Center
2005-2024
University of Utah
2023
Anyang University
2018
Catholic University of Korea
2008-2017
National Institute of Meteorological Sciences
2015
Hanyang University Seoul Hospital
2011-2013
Samsung Medical Center
2009
Sungkyunkwan University
2009
Global warming and climate change have increased the pollen burden frequency intensity of wildfires, sand dust storms, thunderstorms, heatwaves—with concomitant increases in air pollution, heat stress, flooding. These environmental stressors alter human exposome trigger complex immune responses. In parallel, pollutants, allergens, other factors increase risks skin mucosal barrier disruption microbial dysbiosis, while a loss biodiversity reduced exposure to diversity impairs tolerogenic...
Rationale: Beginning in 2006, epidemics of a fatal lung injury unknown cause children were observed Korea every spring. A recent study demonstrated that this type children's interstitial disease (chILD) is associated with humidifier disinfectant use.Objectives: To determine the clinical characteristics chILD and to assess whether nationwide suspension sales autumn 2011 affected its incidence.Methods: The suspected cases between 2006 determined by retrospective study. potential causal...
Epidemiological Change of Atopic Dermatitis
It is unclear whether the responses of refractory and common Mycoplasma pneumoniae (MP) pneumonia to macrolides differ. Hence, this study aimed identify biomarkers that may be used distinguish pneumonias caused by MP in children at hospital admission.The included 123 divided into five groups according infection agent treatment protocol: Group I those with without documented viral infection, treated only macrolides; II a combination methylprednisolone; III IV infection; V was control group...
The old calendar of pollens did not reflect current pollen distribution and concentrations that can be influenced by changes weather environment each region in South Korea. A new allergenic was made based on the data obtained eight regions nationwide between 1997 2009. assessed every day at 8 areas (Seoul, Guri, Busan, Daegu, Jeonju, Kwangju, Kangneung, Jeju) for 12 years July 1, June 30, Pollens were collected using Burkard 7-day sampler (Burkard Manufacturing Co Ltd, UK). which stained...
fects such as renal toxicity.Approximately 20% of patients discontinue cyclosporine treatment within 2 years because adverse effects. 5,6ntravenous immunoglobulin (IVIg) is prepared by cold ethanol fractionation pooled plasma, followed additional viral inactivation procedures.The final product a pure concentrate IgG (with small amounts IgA and IgM) with intact function minimal impurities. 7,8The immunomodulatory mechanism IVIg thought to be mediated interactions the Fc portion receptors...
Children with allergies are at greater risk of becoming sensitized to allergenic pollens in response environmental changes. This study investigated the relationship between changes pollination associated meteorologic and sensitization rates children tree pollen allergens metropolitan area Seoul, Korea.The population consisted 8,295 who visited pediatric allergy clinics Hanyang University Seoul Guri Hospital for symptoms January 1, 1998, December 31, 2019. Pollen was collected two hospitals...
The prevalence of allergic diseases in children has increased for several decades.We evaluated the correlation between pollen count weeds and their sensitization rate Seoul, 1997Seoul, -2009.Airborne particles carrying allergens were collected daily from 3 stations around Seoul.Skin prick tests to performed on with diseases.Ragweed gradually 1999 2005, decreased after 2005 plateaued until 2009 (peak counts, 67 2003, 145 83 grains/m / day 2007).Japanese hop 2002 212 2006 492 /day...
Bee pollen is granules packed by honey bees and widely consumed as natural healthy supplements. pollen-induced anaphylaxis has rarely been reported, its allergenic components have never studied. A 40-year-old male came to the emergency room with generalized urticaria, facial edema, dyspnea, nausea, vomiting, abdominal pain, diarrhea 1 hour after ingesting one tablespoon of bee pollen. Oxygen saturation was 91%. His symptoms resolved injection epinephrine, chlorpheniramine, dexamethasone. He...
Epidemiological evidence suggests that obesity is associated with inflammation of the respiratory tract and pathogenesis asthma. The purpose this study was to examine role phospholipase D1 (PLD1) in leptin-induced expression proinflammatory cytokine, tumor necrosis factor (TNF)-α, suggest a molecular link between inflammation. We investigated whether leptin, typical adipocytokine, plays TNF-α through increased PLD1 activity Raw 264.7. Leptin enhanced activation PLCγ Src, while siRNA...
Food is closely associated with the pathogenesis of atopic dermatitis. allergy usually mediated by IgE antibody to specific food proteins and determination basis common diagnostic test for allergy. IgG4 have been reported as blocking protective effects may be clear in inhalant However, role still a matter debate. In this study, clinical significance allergen-specific IgE/IgG4 dermatitis was investigated compared that IgE. A total 97 patients who fulfilled criteria participated study. Skin...
Purpose:The occurrence of pollen allergy is subject to exposure pollen, which shows regional and temporal variations.We evaluated the changes in counts skin positivity rates for 6 years, explored correlation between their annual change. Materials Methods:We assessed number grains collected Seoul, retrospectively reviewed results 4442 skin-prick tests conducted at Severance Hospital Allergy-Asthma Clinic from January 1, 2008 December 31, 2013.Results: For mean monthly total count showed two...
Purpose:The pollen calendar is the simplest forecasting method for concentrations.As concentrations are liable to seasonal variations due alterations in climate and land-use, it necessary update using recent data.To attenuate impact of considerable temporal spatial variability on calendar, essential employ a new methodology its creation.Methods: A was produced Korea data from observations, creating proposed, considering both risk levels resolution concentrations.A probability distribution...
To validate the prevalence rate of symptoms asthma produced by phase I ISAAC (International Study Asthma and Allergies in Childhood) study, hypertonic saline challenge test was carried out during II study at a year after study. For six middle schools from three cities were selected. Finally, 499 children who responded to both studies analyzed. All subjects asked complete written questionnaire (WQ) first, followed video (AVQ 3.0) Of children, only 19 (3.8%) positive bronchial test. The degree...
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • The analgesic and anti‐inflammatory efficacy of dexibuprofen compared with ibuprofen in adults osteoarthritis, rheumatoid arthritis dental pain. STUDY ADDS Dexibuprofen is as effective tolerable ibuprofen, a dose 5 mg kg −1 would be sufficient to control fever caused by upper respiratory tract infection children. AIM To evaluate the antipyretic tolerability children (URTI). METHODS study population consisted aged 6 months 14 years. At time visit...
The differences between respiratory syncytial virus (RSV) and influenza A (IFAV) in the pathogenesis of wheezing young children have not been clearly defined. aim this study was to assess contributions RSV vs IFAV upper airway inflammation wheezy children. We compared interleukin (IL)‐6, IL‐8, IL‐11, interferon‐γ (IFN‐γ) levels nasopharyngeal aspirates (NPA) from non‐asthmatic with infections (RSV 17 13 children), asthmatic viral nine children, 10 22 unaffected healthy (controls). Levels...