A5100735589- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Eosinophilic Esophagitis
- Contact Dermatitis and Allergies
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Nutrition, Health and Food Behavior
- Food Safety and Hygiene
- Infant Health and Development
- Inhalation and Respiratory Drug Delivery
- Neonatal Respiratory Health Research
- Drug-Induced Adverse Reactions
- Pediatric health and respiratory diseases
- Probiotics and Fermented Foods
- Urticaria and Related Conditions
- Diverse Approaches in Healthcare and Education Studies
- Education and Learning Interventions
- Physics of Superconductivity and Magnetism
- Blood properties and coagulation
- Recycling and Waste Management Techniques
- Food Quality and Safety Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- SARS-CoV-2 and COVID-19 Research
- Korean Urban and Social Studies
- Healthcare and Venom Research
Ajou University
2016-2025
Celltrion (South Korea)
2022-2025
Fukuoka Higashi Medical Center
2024
Chosun University
2023
Hobart and William Smith Colleges
2022
Hannam University
2022
Yonsei University
1992-2019
Ajou University Hospital
2013-2019
University of Chicago
2019
Pusan National University Yangsan Hospital
2019
Controversy exists regarding the preventive effect of probiotics on development eczema or atopic dermatitis. We investigated whether supplementation prevents in infants at high risk. In a randomized, double-blind, placebo-controlled trial, 112 pregnant women with family history allergic diseases received once-daily supplement, either mixture Bifidobacterium bifidum BGN4, B. lactis AD011, and Lactobacillus acidophilus AD031, placebo, starting 4-8 wks before delivery continuing until 6 months...
Rationale: Beginning in 2006, epidemics of a fatal lung injury unknown cause children were observed Korea every spring. A recent study demonstrated that this type children's interstitial disease (chILD) is associated with humidifier disinfectant use.Objectives: To determine the clinical characteristics chILD and to assess whether nationwide suspension sales autumn 2011 affected its incidence.Methods: The suspected cases between 2006 determined by retrospective study. potential causal...
Reducing transaction costs by means of policy intervention could generate comparative advantages and contribute to the growth international trade. Chinese government agencies have introduced a number policies in support rapidly growing cross-border e-commerce promote China’s However, previous literature has not empirically verified precise effect these on trade while focusing impact distance consumer welfare. To address this gap, paper investigates context China, mainly from perspective cost...
Abstract Background The epidemiology and management of anaphylaxis are not well‐reported in Asia. Methods A regional pediatric registry was established by the Asia‐Pacific Research Network for Anaphylaxis (APRA), using standardized protocols prospective data collection, to evaluate triggers region. Pediatric patients below 18 years presenting with across four Asian countries/cities (Thailand, Singapore, Hong Kong (HK), Qingdao) were included. Allergen triggers, symptoms, severity, compared....
Asthma and allergic diseases are one of the most common disorders in children. Due to its increased prevalence, as well morbidity mortality from these diseases, asthma have come be recognized a major worldwide public health issue. In addition, socioeconomic burden also has Korea. The International Study Allergies Childhood (ISAAC) investigated prevalence other using simple standardized methods because comparison between countries. Korea, several epidemiologic studies been conducted determine...
Purpose: Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups.We aimed to identify by Korean children.Methods: We performed a retrospective review of medical records for children diagnosed with between 2009 and 2013 23 secondary or tertiary hospitals South Korea.Results: A total 991 cases (mean age=5.89±5.24)were reported, 63.9% involving patients younger than 6 years 66% male children.Food was the...
DDX3 is a member of the DEAD-box RNA helicase family, involved in mRNA metabolism, including transcription, splicing, and translation. We previously identified as hepatitis B virus (HBV) polymerase (Pol) binding protein, by using transient transfection, we found that inhibits HBV replication at posttranscriptional level, perhaps following encapsidation. To determine exact mechanism inhibition, here employed diverse experimental system. Inconsistently, DDX3-mediated inhibition occurs level...
The occurrence of numerous cases interstitial lung disease in children (chILD) every spring Korea starting 2006 raised suspicion about a causal relationship with the use humidifier disinfectants (HDs). aim this study was to evaluate association between HD and risk chILD.This retrospective, 1∶3 matched case-control consisted 16 chILD that had developed 2010 2011. three groups parallel controls (patients acute lobar pneumonia, asthma, healthy children) were by age, gender, index date....
Background Although cesarean delivery and prenatal exposure to antibiotics are likely affect the gut microbiome in infancy, their effect on development of atopic dermatitis (AD) infancy is unclear. The influence individual genotypes these relationships also To evaluate with a prospective birth cohort study whether section, antibiotics, susceptible act additively promote AD infancy. Methods Cohort for Childhood Asthma Allergic Diseases (COCOA) was selected from general Korean population. A...
Purpose: Age-based causes and clinical characteristics of immediate-type food allergy (FA) have not been sufficiently studied.Therefore, we investigated age-dependent profiles FA in Korean children through an extensive multicenter investigation.Methods: Using a case report form developed by the authors, retrospective medical record review was performed patients (0-18 years old) diagnosed with between September 2014 August 2015 14 tertiary hospitals Korea.Results: A total 1,353 adolescents,...
Abstract Background Probiotic therapies, mainly live bacteria, have been proven to be effective in treating atopic dermatitis (AD) with some controversies. Killed probiotics or postbiotics would immunomodulatory effect allergic diseases including AD. This study was performed evaluate the therapeutic and safety of tyndallized Lactobacillus rhamnosus (IDCC 3201, isolated from feces a Korean breastfed infant, repeated heat‐treated incubated, RHT3201) children Methods In randomized,...
Abstract CpG oligodeoxynucleotides (CpG-ODN) administered during Ag sensitization or before challenge can inhibit allergic pulmonary inflammation and airway hyperreactivity in murine models of asthma. In this study, we investigated whether CpG-ODN reverse an ongoing reaction a mouse model AKR mice were sensitized with conalbumin followed by two intratracheal challenges at weekly intervals. was 24 h after the first challenge. administration reduced Ag-specific IgE levels, bronchoalveolar...
The exact role of the cystic fibrosis transmembrane conductance regulator (CFTR) in pathophysiology, and mechanisms regulating its expression are poorly understood. CFTR gene is known to be genetically or epigenetically associated with several cancers. In present study, methylation status promoter region primary non-small cell lung cancer (NSCLC) were investigated.The NSCLC tissue was assessed by pyrosequencing methylation-specific PCR. Expression analysed real-time PCR, reactivation...
ABSTRACT While collaboration among individuals, work groups, and organizations is central for understanding the performance of public agencies, most studies have focused on between or sectors. We develop a model that focuses two types collaborative behavior: persons (both horizontal vertical) units. empirically test our hypotheses using data perceptions agency from United States federal government. introduce method estimating impact different behavior also accounts nonlinear effects...
Background: Anaphylaxis is increasing in young children.The aim of the present study was to analyze clinical characteristics anaphylaxis Korean infants, with a focus on food triggers. Methods:The analyzed medical records infants aged 0 2 years old who had been diagnosed 23 secondary or tertiary hospitals Korea.Results: We identified 363 cases infantile (66.9% male).Cutaneous symptoms were most prevalent (98.6%), followed by respiratory (83.2%), gastrointestinal (29.8%), and neurologic...
The prevalence of food allergy and food-induced anaphylaxis in children is increasing worldwide. Cow's milk, hen's eggs, wheat allergies young have a more favorable prognosis with relatively early outgrow, while to peanuts, tree nuts, seafood are likely be persistent. Although our understanding the mechanism underlying resolution incomplete, roles dendritic cells, regulatory T B cells important. Many past studies on natural course were retrospective analyses specific study groups, but...