A5004151297- Mast cells and histamine
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Polyamine Metabolism and Applications
- Immune Cell Function and Interaction
- Eosinophilic Esophagitis
- Drug-Induced Adverse Reactions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Monoclonal and Polyclonal Antibodies Research
- Eosinophilic Disorders and Syndromes
- Cell Adhesion Molecules Research
- IL-33, ST2, and ILC Pathways
- T-cell and B-cell Immunology
- Contact Dermatitis and Allergies
- Receptor Mechanisms and Signaling
- Dermatology and Skin Diseases
- melanin and skin pigmentation
- Click Chemistry and Applications
- Fibroblast Growth Factor Research
- Virology and Viral Diseases
- Immunotherapy and Immune Responses
- Cellular transport and secretion
- Healthcare and Venom Research
Stanford University
2015-2024
Stanford Medicine
2005-2024
University School
2019-2024
Rockefeller University
1987-2024
Parker Hannifin (United States)
2015-2024
Palo Alto University
2017-2023
Misgav Ladach
2022
Universidad de Salamanca
2022
Institute for Asthma and Allergy
2016-2020
Stanford Blood Center
2020
Tumor ascites fluids from guinea pigs, hamsters, and mice contain activity that rapidly increases microvascular permeability. Similar is also secreted by these tumor cells a variety of other cell lines in vitro. The permeability-increasing purified either the culture medium or fluid one tumor, pig line 10 hepatocarcinoma, 34,000- to 42,000-dalton protein distinct known permeability factors.
At no time in recent memory has it been so difficult to offer succint generalizations about the biology of mast cell, or its role health and disease. This situation is something a paradox, since there have significant advances experimental approaches for analyzing cell development, biochemistry function, application these methods already generated much important new data. However, some findings required that certain widely held beliefs be reevaluated. Indeed, virtually every facet cell's...
In response to IgE and specific multivalent antigen, mast cell lines (both growth factor-dependent -independent) induce the transcription and/or secretion of a number cytokines having wide spectrum activities. We have identified IL-1, IL-3, IL-5, IL-6, IFN-gamma, GM-CSF, JE, MIP1 alpha, beta, TCA3 RNA in at least two four clones. The production these products (except JE) is activation-associated can be induced by plus antigen. selected instances cytokine expression also activation with Con A...
Both connective tissue mast cells and grown in vitro are derived from multipotential hematopoietic stem cells, but these two cell populations exhibit many differences morphology, biochemistry, function. We investigated whether the phenotype of cultured or their progeny was altered when were transferred into different locations vivo. Cultured immature by ultrastructure, stained with alcian blue neither safranin berberine sulfate, a fluorescent dye that binds to heparin granules. By contrast,...