- Contact Dermatitis and Allergies
- Occupational exposure and asthma
- Allergic Rhinitis and Sensitization
- Dermatology and Skin Diseases
- Drug-Induced Adverse Reactions
- Chemotherapy-related skin toxicity
- Eosinophilic Disorders and Syndromes
- Pesticide Exposure and Toxicity
- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cutaneous lymphoproliferative disorders research
- Dermatological and COVID-19 studies
- Cancer and Skin Lesions
- Food Allergy and Anaphylaxis Research
- Nail Diseases and Treatments
- Vasculitis and related conditions
- Synthesis and properties of polymers
- Systemic Lupus Erythematosus Research
- Psoriasis: Treatment and Pathogenesis
- Nonmelanoma Skin Cancer Studies
- Asthma and respiratory diseases
- Autoimmune and Inflammatory Disorders
- T-cell and B-cell Immunology
- Renal Diseases and Glomerulopathies
Hospital Universitario de La Princesa
2016-2025
University of Monterrey
2024
Universidad Autónoma de Madrid
1998-2022
Hospital Universitario Fundación Jiménez Díaz
2018
Weatherford College
1999
A few months ago, we reported that to consider vesicular exanthems associated with COVID-19, varicella-zoster virus (VZV) and herpes simplex must be ruled out.1 The natural history of zoster is influenced by the immune status host. Reactivation age-related immunosenescence, disease-related immunocompromised state, or iatrogenic immunosuppression, age being major risk factor for most cases zoster. Among VZV reactivation triggers, vaccines are not common, excluding appearing after vaccination,...
Background. The pattern of contact sensitization to the supposedly most important allergens assembled in baseline series differs between countries, presumably at least partly because exposure differences. Objectives. To describe prevalence tested consecutive patients years 2007 and 2008, discuss possible Methods. Data from 39 departments 11 European countries comprising Surveillance System on Contact Allergy network ( www.essca‐dc.org ) this period have been pooled analysed according common...
Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, such as introduction of new substances, products formulations regulatory intervention, the spectrum contact sensitization changes.To evaluate current allergens present European baseline series (EBS) across Europe.Retrospective analysis data collected by Surveillance System on Allergies (ESSCA, www.essca-dc.org) consecutively patch-tested patients, 2013/14,...
Although cases of lichen planus (LP) associated with hepatitis C virus (HCV) infection have been described, the association between two diseases has not established because geographic origin patients could be an important factor in HCV prevalence LP. The serum samples 78 consecutive cutaneous and/or mucous LP and 82 control were analysed for presence antibodies to by enzyme-immunoassay antigens two-stage polymerase chain reaction (PCR). clinical features compared without infection. Sixteen...
Abstract Background Allergic contact dermatitis caused by biocides is common and causes significant patient morbidity. Objective To describe the current frequency pattern of patch test reactivity to biocide allergens included in baseline series most European countries. Methods Data collected Surveillance System on Contact Allergies ( ESSCA ) network between 2009 2012 from 12 countries were analysed. Results Methylisothiazolinone 0.2% aq. produced highest prevalence sensitization during study...
Clinical surveillance of the prevalence contact allergy in consecutively patch tested patients is a proven instrument to continually assess importance allergens (haptens) assembled baseline series.To present current results from European Surveillance System on Contact Allergies, including 13 countries represented by 1 11 departments.Anonymized or pseudonymized test and clinical data various capture systems used locally nationally as transferred Erlangen centre were pooled descriptively...
Atopic dermatitis (AD) affects both children and adults. The main symptom of this disease is pruritus, which impacts health-related quality life (HRQOL). aim study was to evaluate the impact AD on lives adults with disease.This a multicenter prospective epidemiological (2-17 years) (≥ 18 selected from dermatology offices in Spain. patients had all for at least year no other chronic inflammatory skin diseases. In addition sociodemographic information, data collected included clinical features...
Abstract Background A global epidemic of allergic contact dermatitis to (meth)acrylates has been described in relation the widespread use manicure products. Objectives To evaluate frequency sensitization 2‐hydroxyethyl methacrylate (2‐HEMA) among consecutively patch tested patients with eczema Spain; percentage current relevance; MOAHLFA index; and, potential sources exposure (meth)acrylates. Methods From January 2019 December 2022, 2‐HEMA 2% pet. was prospectively 24 REIDAC (Spanish...
Despite advances in treatments for atopic dermatitis (AD), information regarding its impact and interaction with comorbidities (such as asthma, rhinoconjunctivitis, ocular pathology) is limited. This study aims to assess the clinical epidemiological characteristics of patients AD, well treatment response, taking into consideration these comorbidities. Data were analyzed from multicenter BIOBADATOP registry, that represents a prospective cohort AD initiating systemic treatment. A descriptive...
Atopic dermatitis (AD) affects both children and adults. The main symptom of this disease is pruritus, which impacts health-related quality life (HRQOL). aim study was to evaluate the impact AD on lives adults with disease. This a multicenter prospective epidemiological (2-17 years) (≥ 18 selected from dermatology offices in Spain. patients had all for at least year no other chronic inflammatory skin diseases. In addition sociodemographic information, data collected included clinical...
Contact allergy to fragrances is common, and impairs quality of life, particularly in young women.To provide current results on the prevalences sensitization fragrance allergens used as markers baseline series most European countries.Data patients consecutively patch tested between 2009 2012 12 countries with contained were collected by Surveillance System Allergies network descriptively analysed. Four departments TRUE Test(®) system.The 'basic markers' 51 477 [fragrance mix II (FM II)] 57...
Background Analyses of the European Surveillance System on Contact Allergies (ESSCA) database have focused primarily prevalence contact allergies to baseline series, both overall and in subgroups patients. However, affected body sites hitherto not been addressed. Objective To determine for distinct patients with allergic dermatitis (ACD). Methods Analysis data collected by ESSCA ( www.essca‐dc.org ) consecutively patch tested patients, from 2009 2014, eight countries was performed. Cases...
According to the literature, palmoplantar lesions in lichen planus (LP) are uncommon, and do not usually have classically described clinical morphology. The aim of this study was evaluate prevalence LP describe characteristic clinicopathological appearances affecting palms soles. Palmoplantar with accompanying skin involvement accounted for 26% our cases. presence very pruriginous erythematous scaly and/or hyperkeratotic plaques, well-defined edges, located on internal plantar arch, without...
Abstract Background Perforating granuloma annulare (PGA) is considered an histologic subtype of (GA) and it described as a very rare disease, usually children, affecting the dorsum hands. Mechanisms leading to perforation are unknown. Our experience suggested different clinical presentation, so we decided review our patients cases published. Methods We present six PGA 52 reported in literature. Data regarding sex, age, time evolution features, laboratory findings, treatment, follow‐up were...
Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered reflect increased susceptibility developing a contact allergy, and likely be associated with an impaired quality of life.To evaluate prevalences polysensitization across Europe analyse factors polysensitization.Patch test data collected by Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients January 2009 December 2014,...
Abstract Schnitzler's syndrome (SS) is a rare entity characterized by the association of chronic urticaria and monoclonal IgM gammopathy. Usually, intermittent fever, arthralgia elevation erythrocyte sedimentation rate also occur. We report patient with same symptoms, but IgG instead paraproteinaemia. Histological examination urticarial lesions showed signs leucocytoclastic vasculitis. After 20 years therapeutic failure, cyclosporin has achieved total clearance in our patient. Two previous...
Background Fragrance chemicals constitute the second most frequent cause of contact allergy in Spain. There are no data available concerning individual fragrances that frequently involved. Objectives To describe diagnostic contribution provided by specific fragrance series to results obtained with baseline markers correlating both series. Materials and methods We performed a 5‐year retrospective study marker‐positive patients tested 23 Spanish centres. collected demographic clinical...
Macular lymphocytic arteritis describes a recently reported entity, clinically characterized by asymptomatic hyperpigmented macules on the lower limbs, without association of systemic diseases. Histopathologically it is with hyalinized fibrin ring. We report new case presenting ulceration, finding not previously described. A 25‐year‐old Hispanic woman was evaluated for 1‐year history gradually progressive, eruption that begins at level both knees and progressively affects legs feet. She also...
Abstract Background There is considerable variability across European patch test centres as to which allergens are included in local and national cosmetics series. Objectives To propose a standardized, evidence‐based cosmetic series for Europe based on up‐to‐date analysis of relevant contact allergens. Methods We collated data from the Surveillance System Contact Allergies (ESSCA) 2009 2018 determine produce high yield allergy. with prevalence >0.3% that were considered included. Rare...
Irritant contact dermatitis (ICD) is caused by the acute locally toxic effect of a strong irritant, or cumulative exposure to various weaker physical and/or chemical irritants.