A5076910765- Dermatology and Skin Diseases
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Occupational exposure and asthma
- Food Allergy and Anaphylaxis Research
- Nail Diseases and Treatments
- Asthma and respiratory diseases
- Medicine and Dermatology Studies History
- Autoimmune Bullous Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health and Medical Studies
- Drug-Induced Adverse Reactions
- Medical Practices and Rehabilitation
- Dermatological diseases and infestations
- Pesticide Exposure and Toxicity
- Pharmacological Effects of Natural Compounds
- Skin and Cellular Biology Research
- Complementary and Alternative Medicine Studies
- Delphi Technique in Research
- Dermatological and Skeletal Disorders
- Bacillus and Francisella bacterial research
- Medical and Health Sciences Research
- Autoimmune and Inflammatory Disorders
Heidelberg University
2016-2025
University Hospital Heidelberg
2016-2025
Hautklinik Heidelberg
2019-2025
Chirurgische Universitätsklinik Heidelberg
2023
University Hospital Münster
2012-2023
Universitätsmedizin Greifswald
2023
Oxfam
2023
Liechtenstein Institute
2023
John Wiley & Sons (United States)
2023
Hudson Institute
2023
Chronic itch is a common and distressing symptom that arises from variety of skin conditions systemic diseases. Despite this, there no clinically based classification pruritic diseases to assist in the diagnosis cost-effective medical care patients with pruritus. The proposed focuses on clinical signs distinguishes between without primary or secondary lesions. Three groups are proposed: pruritus diseased (inflamed) (group I), non-diseased (non-inflamed) II), presenting severe chronic scratch...
Pruritus is a frequent symptom in medicine. Population-based studies show that every 5th person the general population has suffered from chronic pruritus at least once lifetime with 12-month incidence of 7%. In patient populations its frequency much higher depending on underlying cause, ranging around 25% haemodialysis patients to 100% skin diseases such as urticaria and atopic dermatitis (AD). may be result dermatological or non-dermatological disease. Especially non-diseased it caused by...
Pruritus is the most frequent symptom in dermatology. Its impact on quality of life substantial. Epidemiological data chronic pruritus (>?6 weeks) at population level sparse, but important order to understand burden and risk factors this distressing symptom. The aim population-based cross-sectional study was estimate point, 12-month lifetime prevalence pruritus, assessing its association with sociodemographic variables describing characteristics. A validated postal questionnaire sent 4,500...
Elke WEISShAAr1, Jacek C. SzEpIEToWSkI2, Ulf DArSoW3, Laurent MISEry4, Joanna WALLENgrEN5, Thomas METTANg6, Uwe gIELEr7, Torello LoTTI8, Julien LAMbErT9, peter MAISEL10, Markus STrEIT11, Malcolm W. grEAVES12, Andrew CArMIChAEL13, Erwin TSChAChLEr14, Johannes rINg3 and Sonja STaNDEr15 1Department of Clinical Social Medicine, Environmental Occupational Dermatology, Ruprecht-Karls-University Heidelberg, Germany, 2Department Venereology Allergology, Wroclaw Medical University, Poland,...
Abstract Background The term prurigo has been used for many decades in dermatology without clear definition, and currently terminology of is inconsistent confusing. Especially, itch‐related remains unexplored regarding the epidemiology, clinical profile, natural course, underlying causes, available treatments economic burden, although burdensome difficult to treat. Objective To address these issues, multicentre European Prurigo Project (EPP) was designed increase knowledge on chronic (CPG)....
Sensitive skin is a frequent complaint in the general population, patients, and among subjects suffering from itch. The International Forum for Study of Itch (IFSI) decided to initiate special interest group (SIG) on sensitive skin. Using Delphi method, was defined as "A syndrome by occurrence unpleasant sensations (stinging, burning, pain, pruritus, tingling sensations) response stimuli that normally should not provoke such sensations. These cannot be explained lesions attributable any...
Hand eczema is a common inflammatory skin disorder. Health care providers need continuously updated information about the management of hand to ensure best treatment for their patients.To update European Society Contact Dermatitis guideline on diagnosis, prevention, and eczema.The Guideline Development Group (GDG) was established behalf ESCD. A call interest launched via ESCD website members' mailing list. Appraisal evidence therapeutic preventive interventions applied structured method...
Pruritus is the most frequent and distressing symptom associated with dermatoses various internal neurological diseases.To investigate two different populations of patients pruritus, one in Germany Uganda, a particular focus on clinical characteristics, aetiology quality life.We investigated by questionnaire 132 (59 men, 73 women, mean age 54.5 years) who were referred to Department Dermatology at University Hospital Magdeburg, Germany, diagnosis pruritus as leading symptom. The was also...
This is the report from fifth meeting of Harmonising Outcome Measures for Eczema initiative (HOME V). The was held on 12–14 June 2017 in Nantes, France, with 81 participants. main aims were (i) to achieve consensus over definition core domain long‐term control and how measure it (ii) prioritize future areas research measurement quality life (QoL) children. Moderated whole‐group small‐group discussions informed by presentations qualitative studies, systematic reviews validation studies....
Epidemiological data on chronic pruritus (> 6 weeks) in the general population are sparse. We aimed to provide incidence and prevalence of pruritus, identify its determinants based cross-sectional longitudinal analyses. A cohort 1,190 participants from a baseline-study (response rate: 57.8%) was followed up after one year. The questionnaire assessed occurrence medical, lifestyle psychosocial variables. Incident defined as reported at follow-up those subjects free-of-the-symptom baseline....
This article is a report of the fourth meeting Harmonising Outcome Measures for Eczema (HOME) initiative held in Malmö, Sweden on 23–24 April 2015 (HOME IV). The aim was to achieve consensus over preferred outcome instruments measuring patient‐reported symptoms and quality life HOME core set atopic eczema (AE). Following presentations, which included data from systematic reviews, discussions were mixture whole group small discussions. Small groups allocated priori ensure representation...
Summary Background A tertiary individual prevention programme ( TIP ) is offered to patients with severe occupational skin disease OSD in Germany. Previously, it was shown that the burden of s considerably reduced up 1 year after . Objectives To evaluate long‐term effects Patients and methods In a prospective multicentre cohort study, clinical patient‐reported outcome data 3 years were evaluated. Results Of 1788 initially included 1410 available for 3‐year follow‐up analysis. The severity ,...
Summary Background There is little knowledge about the costs of occupational hand eczema. Objectives To estimate societal patients with eczema in Germany. Methods Resource use during past year, disease severity and quality life [Dermatology Life Quality Index (DLQI)] were gathered for before they entered a special rehabilitation programme. Costs calculated from perspective. The analysis focused on all groups no signs/mild (group A) moderate to severe B). Results One hundred fifty‐one...
Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, such as introduction of new substances, products formulations regulatory intervention, the spectrum contact sensitization changes.To evaluate current allergens present European baseline series (EBS) across Europe.Retrospective analysis data collected by Surveillance System on Allergies (ESSCA, www.essca-dc.org) consecutively patch-tested patients, 2013/14,...
BackgroundAnecdotal evidence suggests that neurokinin 1 receptor antagonism reduces pruritus intensity in chronic pruritic conditions such as prurigo nodularis (PN).ObjectiveThis study assessed safety and efficacy of the antagonist serlopitant for treatment PN.MethodsIn this randomized, double-blind, placebo-controlled study, 128 patients with chronic, treatment-refractory PN more than 6 weeks received serlopitant, 5 mg, or placebo orally once daily 8 weeks. The primary end point was change...
Summary Epicutaneous patch testing is the diagnostic standard for detection of allergic contact dermatitis. The present guidelines are aimed at residents and board‐certified physicians in fields dermatology allergology as well other medical specialties involved establishing indication its execution patients with dermatitis forms delayed‐type hypersensitivity. target audience also includes health care providers insurance funds. Based on a systematic literature search formal consensus process...
Chronic prurigo (CPG) is a highly burdensome pruritic disease characterized by chronic itch, prolonged scratching behavior and the development of localized or generalized hyperkeratotic pruriginous lesions. Neuronal sensitization an itch-scratch cycle contribute to augmentation pruritus chronicity disease. We provide here first international guideline for rational diagnostic therapeutic approach CPG. Recommendations are based on available evidence expert opinion. The diagnosis CPG made...
Continual analyses of patch test results with the European baseline series (EBS) serve both contact allergy surveillance and auditing value included allergens.To present current EBS testing, obtained in 53 departments 13 countries during 2019 2020.Anonymised or pseudonymised individual data partly aggregated on demographic/clinical characteristics rest were prospectively collected centrally pooled analysed.In 2020, 22 581 patients tested EBS. Sensitization to nickel remained most common...
Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden affected individual society.To present sensitization frequencies most relevant allergens of European baseline series patients (OCD) compare profiles different occupations.The data 16 022 considered having OCD after patch testing within Surveillance System on Contact...