A5066823991- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Contact Dermatitis and Allergies
- Health and Medical Studies
- Delphi Technique in Research
- Transgenic Plants and Applications
- Health, psychology, and well-being
- Eating Disorders and Behaviors
- Psoriasis: Treatment and Pathogenesis
- Urticaria and Related Conditions
- Advancements in Transdermal Drug Delivery
- Biotin and Related Studies
- Polydiacetylene-based materials and applications
- Neonatal skin health care
- Herbal Medicine Research Studies
- Health and Well-being Studies
- Stroke Rehabilitation and Recovery
- Nail Diseases and Treatments
- Complementary and Alternative Medicine Studies
Universidade de São Paulo
2012-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2017-2024
Hospital de Clínicas
2024
Hospital São Paulo
2018-2023
Odense University Hospital
2017
Kyoto Koka Women's University
2016
Oregon Health & Science University
2008
University of British Columbia
2003
Novartis (Switzerland)
2003
Goethe University Frankfurt
2003
Abstract The use of nonstandardized and inadequately validated outcome measures in atopic eczema trials is a major obstacle to practising evidence‐based dermatology. Harmonising Outcome Measures for Eczema ( HOME ) initiative an international multiprofessional group dedicated outcomes research. In June 2011, the conducted consensus study involving 43 individuals from 10 countries, representing different stakeholders (patients, clinicians, methodologists, pharmaceutical industry) determine...
This article is a report of the fourth meeting Harmonising Outcome Measures for Eczema (HOME) initiative held in Malmö, Sweden on 23–24 April 2015 (HOME IV). The aim was to achieve consensus over preferred outcome instruments measuring patient‐reported symptoms and quality life HOME core set atopic eczema (AE). Following presentations, which included data from systematic reviews, discussions were mixture whole group small discussions. Small groups allocated priori ensure representation...
The International Society of AD (ISAD) organized a roundtable on global aspects at the WCD 2023 in Singapore. According to Global Burden Disease (GBD) consortium, least 171 million individuals were affected with 2019, corresponding 2.23% world population, age-standardized prevalence and incidence rates that relatively stable from 1990 2019. Based panel experience, most cases are mild-to-moderate. Without parallel data disease severity, GBD difficult interpret many regions. This gap is...
Abstract Therapeutic patient education ( TPE ) has proven effective in increasing treatment adherence and improving quality of life (QoL) for patients with numerous chronic diseases, especially atopic dermatitis AD ). This study was undertaken to identify worldwide experiences treatment. Experts from 23 hospitals, located 11 countries, responded a questionnaire on 10 major items. Patients programs were mainly children adolescents moderate severe or markedly affected QoL. Individual...
Adherence to topical corticosteroids (TCS) is essential for the effective treatment of atopic dermatitis but can be limited by concerns about their use. This study examined feasibility applying validated TOPICOP score assessing TCS phobia across different countries.This was a prospective multicentre conducted in 21 hospitals 17 countries. Patients >3 months age with or parents legal representatives completed translation questionnaire country's native language. Respondents also questionnaires...
Abstract Background Atopic dermatitis (AD) is a chronic dermatosis, predominant in childhood, characterized by pruritus and eczematous‐type lesions with xerosis as the prominent clinical sign. Objectives To analyze correlation between biophysical measurements of skin barrier function other assessment criteria severity according to Rajka Langeland’s criteria. Methods Biophysical [transepidermal water loss (TEWL) corneometry] were obtained from 120 patients diagnosis AD. Serum levels IgE also...
Atopic dermatitis is a highly prevalent inflammatory and pruritic dermatosis with multifactorial etiology, which includes skin barrier defects, immune dysfunction, microbiome alterations. mediated by genetic, environmental, psychological factors requires therapeutic management that covers all the aspects of its complex pathogenesis.The aim this article to present experience, opinions, recommendations Brazilian dermatology experts regarding atopic dermatitis.Eighteen from 10 university...
Abstract Background The first International Society of Atopic Dermatitis ( ISAD ) global meeting dedicated to atopic dermatitis AD in Sub‐Saharan Africa SSA was held Geneva, Switzerland April 2019. A total 30 participants were present at the meeting, including those from 17 countries, representatives World Health Organization WHO ), Foundation for Dermatology IFD (a committee League Dermatological Societies, ILDS www.ilds.org Fondation pour la Dermatite Atopique, as well specialists...
Abstract Background Atopic dermatitis ( AD ) is a chronic recurrent inflammatory disease, with prevalence of about 10–20% in children and 1–3% adults. S taphylococcus aureus present 80–100% skin from atopic patients related to worsening the disease by action enterotoxins. The aim this study was evaluate profile anti‐ enterotoxin B SEB antibody isotypes IgG subclass levels adult . Methods We selected 38 , diagnosed H anifin R ajka's criteria, aged between 18 65, 26 healthy controls HC )....
Atopic dermatitis (AD) is a chronic inflammatory disease causing intense pruritus, and with typical clinical features. There are few epidemiological studies concerning AD in adults, as well little information about its prognostic. The aim of this study was to evaluate the course adults AD. 80 patients aged above 18 years (mean age = 29 years) were selected (30 males 50 females) interviewed hospitalization, systemic corticoid usage, onset, personal and/or familial history atopy. Disease...
Atopic dermatitis (AD) is a chronic, inflammatory skin disease with high prevalence and complex pathogenesis. The of AD patients usually colonized by Staphylococcus aureus (S. aureus); its exotoxins may trigger or enhance the cutaneous inflammation. Several mediators are related to immune imbalance interleukin-18 (IL-18), an cytokine, play role in atopic inflammation.To evaluate peripheral blood mononuclear cells (PBMC) proliferation response staphylococcal enterotoxins A (SEA) B (SEB)...
This publication is an update of the "Consensus on therapeutic management atopic dermatitis - Brazilian Society Dermatology" published in 2019, considering novel, targeted-oriented systemic therapies for dermatitis. The initial recommendations current consensus treatment patients with were based a recent review scientific data and was reached after voting. Dermatology invited 31 experts from all regions Brazil 2 international who fully contributed to process. methods included e-Delphi study...
Atopic dermatitis (AD) is a chronic inflammatory disease causing intense pruritus, and with typical clinical features. There are few epidemiological studies concerning AD in adults, as well little information about its prognostic. The aim of this study was to evaluate the course adults AD. 80 patients aged above 18 years (mean age = 29 years) were selected (30 males 50 females) interviewed hospitalization, systemic corticoid usage, onset, personal and/or familial history atopy. Disease...
Background: Hydration and integrity of the horny layer is essential to normal skin function. Objective: Comparison hydrating properties three moisturizers with pimecrolimus cream vehicle. Methods: Four test preparations (high-quality cream, cold emulsion, emollient oil, vehicle) were applied four different regions forearms legs. Transepidermal water loss (TEWL) was assessed by evaporimetry at baseline, 3 6 hours after arm application, electrical capacitance corneometry 1, 2, leg application....
Epicutaneous test made with dust mite antigens.Evaluation of the response epicutaneous Aleuroglyphus ovatus antigen in atopic patients.We patch tested 119 individuals, 48 dermatitis, 50 respiratory allergy and 21 healthy controls. We compare positive frequency to a closed using different concentrations 96h reading times among those individuals.Six patients dermatitis (12.5%) 4 atopy (8.0%) had reactions. None non-atopic controls response. As concentration raised, number reactions raised as...