A5087727339- Autoimmune Bullous Skin Diseases
- Skin and Cellular Biology Research
- Genetic and rare skin diseases.
- Academic Research in Diverse Fields
- Vascular Malformations and Hemangiomas
- Dermatology and Skin Diseases
- Systemic Lupus Erythematosus Research
- Tumors and Oncological Cases
- RNA regulation and disease
- Vascular Malformations Diagnosis and Treatment
- Neonatal skin health care
- Urticaria and Related Conditions
- Dermatologic Treatments and Research
- Nail Diseases and Treatments
- Dermatological and Skeletal Disorders
- Vascular Tumors and Angiosarcomas
- Parvovirus B19 Infection Studies
- Cutaneous lymphoproliferative disorders research
- Systemic Sclerosis and Related Diseases
- Monoclonal and Polyclonal Antibodies Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Eosinophilic Disorders and Syndromes
- Histiocytic Disorders and Treatments
- Mast cells and histamine
- Fungal Infections and Studies
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2004-2024
Universidade de São Paulo
2009-2021
Hospital Universitário da Universidade de São Paulo
2012
Universidade Brasil
2006-2011
Hospital de Clínicas
2011
Centro Universitário das Faculdades Metropolitanas Unidas
2010
Abstract Background Cutaneous tuberculosis has re‐emerged in the last 15 years together with higher incidence of pulmonary and multidrug resistance. The choice for a single diagnostic tool among many available today is challenge. Our objective was to compare polymerase chain reaction (PCR) other exams diagnosis cutaneous atypical mycobacteria skin infection. Methods PCR set five different were performed 32 patients (34 samples paraffin‐embedded tissue) evaluated 3 university hospital,...
Atopic dermatitis is a highly prevalent inflammatory and pruritic dermatosis with multifactorial etiology, which includes skin barrier defects, immune dysfunction, microbiome alterations. mediated by genetic, environmental, psychological factors requires therapeutic management that covers all the aspects of its complex pathogenesis.The aim this article to present experience, opinions, recommendations Brazilian dermatology experts regarding atopic dermatitis.Eighteen from 10 university...
OBJECTIVE:To examine the presence of serum antinuclear autoantibodies in a healthy population. METHODS: Serum 500 normal blood donors between 18 and 60 years age were tested for autoantibodies. Antinuclear antibodies detected by indirect immunofluorescence technique using HEp-2 epithelial cells as substrate. The dnaN was Critidia lucillae Anti-SSA (RO), anti-SSB (LA), anti-Sm, anti-RNP determined double radial immunodiffusion. RESULTS: In evaluation antibodies, 22.6% sera. other not...
Abstract: Discoid lupus erythematosus is much less frequent and studied in children. We undertook a retrospective study of 34 children than 16 years age with this disease, seen over period 9 years. A female predominance 2:1 was found. An association between discoid systemic observed 23.5% patients, higher proportion compared to adult erythematosus. Disseminated lesions were more patients criteria for (87.5% vs 34%), suggesting that it could be associated worse prognosis. Histologic findings...
Abstract Background The Quality of Life Evaluation in Epidermolysis Bullosa (Qo LEB ) questionnaire was developed for use English‐speaking individuals. Objectives aims this study were to translate the Qo into Brazilian Portuguese, culturally adapt it, and verify its reliability validity. Methods followed steps proposed by World Health Organization, which include: translation; evaluation a panel experts patients; back linguistic cultural adaptation. All subjects examined assessed using...
PURPOSE: To study and compare the appearance of hairs from patients with Chédiak-Higashi Griscelli-Prunieras syndromes under light polarized microscopy. METHOD: Hairs 2 were obtained examined normal RESULTS: Under microscopy, presented evenly distributed, regular melanin granules, larger than those seen in hairs. shafts exhibited a bright polychromatic refringence appearance. In contrast, hair patients, bigger irregular distributed mainly near medulla. appeared monotonously white....
Epidermolysis bullosa (EB) is a group of rare hereditary diseases, characterized by fragility the skin and mucous membranes. Epidemiological data on EB in Brazil are scarce. To describe epidemiological aspects patients with diagnosed Dermatology Department tertiary hospital, from 2000 to 2022. An observational retrospective study was conducted through analysis medical records. The evaluated included clinical form, sex, family history, consanguinity, age at diagnosis, current age, time...
Infantile hemangiomas (IHs) are the most common benign vascular tumors of childhood. Propranolol is an effective drug in treating IH. A reliable and complementary instrument necessary to evaluate IH response propranolol addition clinical photographic assessments. Ultrasonography a simple non-invasive technique that enables precise measurements tumor size contributes objective follow-up.To demonstrate use serial ultrasonography as adjunctive tool for assessment treatment with propranolol.A...
This publication is an update of the "Consensus on therapeutic management atopic dermatitis - Brazilian Society Dermatology" published in 2019, considering novel, targeted-oriented systemic therapies for dermatitis. The initial recommendations current consensus treatment patients with were based a recent review scientific data and was reached after voting. Dermatology invited 31 experts from all regions Brazil 2 international who fully contributed to process. methods included e-Delphi study...
Abstract Biopsy specimens of cutaneous discoid lesions 71 patients with lupus erythematosus (CLE) were studied. The material was examined by direct immunofluorescence (DIF) to establish positivity and morphologic patterns immunoglobulins complement deposits in the basement membrane zone (BMZ). A correlation between DIF results thickening epidermis (BM) stained periodic acid‐Schiff (PAS), obtained from 31 matched biopsy specimens, also is presented. Direct had positive 66.20% examinations...
A dermatite da área fralda irritativa primária é a mais prevalente desse tipo, sendo provavelmente afecção cutânea freqüente na primeira infância. Constitui fonte significativa de desconforto para criança. O uso ocasiona aumento temperatura e umidade locais. Há conseqüente maceração pele, que se torna susceptível à irritação ocasionada pelo contato prolongado urina das fezes. Freqüentemente surge infecção secundária por Candida albicans ou bactérias como Bacillos faecallis, Proteus,...
Pemphigus are autoimmune intraepidermal blistering diseases in which immunoglobulin G (IgG) autoantibodies directed against desmosomal glycoproteins. The aim of this study was to determine the IgG subclass profile endemic pemphigus foliaceus (fogo selvagem) and vulgaris utilizing indirect immunofluorescence. PATIENTS AND METHODS: Twenty-five patients with vulgaris, 25 selvagem), healthy controls were analyzed by immunofluorescence for circulating (total its subclasses). RESULTS: Our data...
Idiopathic cutaneous hyperchromia of the orbital region (ICHOR) does not have a clear etiopathogenesis. Genetic factors, increased melanin, prominent vasculature, and eyelid skin slackness seem to be involved.To evaluate individuals with ICHOR clinically histologically, before after treatment high-energy pulsed light (HEPL), considering epidermal dermal in order HEPL efficacy clearing away ICHOR, 1 month year later check whether improvement was maintained.Twelve underwent clinical...