Jasvinder A. Singh
- Gout, Hyperuricemia, Uric Acid
- Rheumatoid Arthritis Research and Therapies
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Case Reports on Hematomas
- Orthopedic Infections and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Urticaria and Related Conditions
- Systemic Lupus Erythematosus Research
- Shoulder Injury and Treatment
- Osteoarthritis Treatment and Mechanisms
- Delphi Technique in Research
- Global Public Health Policies and Epidemiology
- Musculoskeletal pain and rehabilitation
- Global Maternal and Child Health
- Botulinum Toxin and Related Neurological Disorders
- Alcohol Consumption and Health Effects
- Global Health Care Issues
- Venous Thromboembolism Diagnosis and Management
- Chronic Lymphocytic Leukemia Research
- Musculoskeletal Disorders and Rehabilitation
- Hepatitis C virus research
- Biosimilars and Bioanalytical Methods
University of Alabama at Birmingham
2016-2025
Birmingham VA Medical Center
2016-2025
University of Minnesota
2006-2025
Michael E. DeBakey VA Medical Center
2024-2025
Alabama Department of Public Health
2013-2025
Baylor College of Medicine
2020-2025
Massachusetts General Hospital
2006-2025
Harvard University
2004-2025
Hormel (United States)
2022-2025
MedStar Franklin Square Medical Center
2025
IMPORTANCECancer is among the leading causes of death worldwide.Current estimates cancer burden in individual countries and regions are necessary to inform local control strategies.OBJECTIVE To estimate mortality, incidence, years lived with disability (YLDs), life lost (YLLs), disability-adjusted life-years (DALYs) for 28 cancers 188 by sex from 1990 2013. EVIDENCE REVIEWThe general methodology Global Burden Disease (GBD) 2013 study was used.Cancer registries were source incidence data as...
The burden of inflammatory bowel disease (IBD) is rising globally, with substantial variation in levels and trends different countries regions. Understanding these geographical differences crucial for formulating effective strategies preventing treating IBD. We report the prevalence, mortality, overall IBD 195 territories between 1990 2017, based on data from Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2017.We modelled mortality due to using a standard Cause Death Ensemble...
Guidelines and recommendations
Network meta-analysis (NMA), combining direct and indirect comparisons, is increasingly being used to examine the comparative effectiveness of medical interventions. Minimal guidance exists on how rate quality evidence supporting treatment effect estimates obtained from NMA. We present a four-step approach in each direct, indirect, NMA based methods developed by GRADE working group. Using an example published NMA, we show that varies high very low across ratings given whole network are...
<h3>Introduction</h3> Several studies have measured health outcomes in the United States, but none provided a comprehensive assessment of patterns by state. <h3>Objective</h3> To use results Global Burden Disease Study (GBD) to report trends burden diseases, injuries, and risk factors at state level from 1990 2016. <h3>Design Setting</h3> A systematic analysis published available data sources estimates disease age, sex, geography, year. <h3>Main Outcomes Measures</h3> Prevalence, incidence,...
<h3>Objective</h3> To develop and validate new classification criteria for adult juvenile idiopathic inflammatory myopathies (IIM) their major subgroups. <h3>Methods</h3> Candidate variables were assembled from published expert opinion using consensus methodology. Data collected 47 rheumatology, dermatology, neurology paediatric clinics worldwide. Several statistical methods used to derive the criteria. <h3>Results</h3> Based on data 976 IIM patients (74% adults; 26% children) 624 non-IIM...
<h3>Context</h3>Total knee arthroplasty (TKA) is one of the most common and costly surgical procedures performed in United States.<h3>Objective</h3>To examine longitudinal trends volume, utilization, outcomes for primary revision TKA between 1991 2010 US Medicare population.<h3>Design, Setting, Participants</h3>Observational cohort 3 271 851 patients (aged ≥65 years) who underwent 318 563 identified Part A data files.<h3>Main Outcome Measures</h3>We examined changes per capita hospital...
Objective. To project future total hip and knee joint arthroplasty (THA, TKA) use in the United States to 2040. Methods. We used 2000–2014 US National Inpatient Sample (NIS) combined with Census Bureau data develop projections for primary THA TKA from 2020 2040 using polynomial regression account nonlinearity interactions between variables, assuming underlying distribution of number THA/TKA be Poisson distributed. performed sensitivity analyses a negative binomial overdispersion. Results....
Lack of standardization outcome measures limits the usefulness clinical trial evidence to inform health care decisions. This can be addressed by agreeing on a minimum core set per condition, containing relevant patients and decision makers. Since 1992, Outcome Measures in Rheumatology (OMERACT) consensus initiative has successfully developed sets for many rheumatologic conditions, actively involving since 2002. Its expanding scope required an explicit formulation its underlying conceptual...
Guidelines and recommendations developed and/or endorsed by the American College of Rheumatology (ACR) are intended to provide guidance for particular patterns practice not dictate care a patient.The ACR considers adherence these guidelines be voluntary, with ultimate determination regarding their application made physician in light each patient's individual circumstances.Guidelines promote beneficial or desirable outcomes but cannot guarantee any specific outcome.Guidelines subject periodic...
To provide guidance for the management of gout, including indications and optimal use urate-lowering therapy (ULT), treatment gout flares, lifestyle other medication recommendations.Fifty-seven population, intervention, comparator, outcomes questions were developed, followed by a systematic literature review, network meta-analyses with ratings available evidence according to Grading Recommendations Assessment, Development Evaluation (GRADE) methodology, patient input. A group consensus...
To develop and validate new classification criteria for adult juvenile idiopathic inflammatory myopathies (IIM) their major subgroups.Candidate variables were assembled from published expert opinion using consensus methodology. Data collected 47 rheumatology, dermatology, neurology, pediatric clinics worldwide. Several statistical methods utilized to derive the criteria.Based on data 976 IIM patients (74% adults; 26% children) 624 non-IIM with mimicking conditions (82% 18% children),...
Objective To provide guidance for the management of gout, including indications and optimal use urate‐lowering therapy ( ULT ), treatment gout flares, lifestyle other medication recommendations. Methods Fifty‐seven population, intervention, comparator, outcomes questions were developed, followed by a systematic literature review, network meta‐analyses with ratings available evidence according to Grading Recommendations Assessment, Development Evaluation GRADE ) methodology, patient input. A...
Brain and CNS cancers (collectively referred to as cancers) are a source of mortality morbidity for which diagnosis treatment require extensive resource allocation sophisticated diagnostic therapeutic technology. Previous epidemiological studies limited specific geographical regions or time periods, making them difficult compare on global scale. In this analysis, we aimed provide comparable comprehensive estimation the burden brain cancer between 1990 2016.We report means 95% uncertainty...