Mark G. Shrime

ORCID: 0000-0002-3546-9867
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About
Contact & Profiles
Research Areas
  • Global Health and Surgery
  • Global Health Workforce Issues
  • Global Maternal and Child Health
  • Global Health Care Issues
  • Cardiac, Anesthesia and Surgical Outcomes
  • Diversity and Career in Medicine
  • Healthcare Systems and Reforms
  • Healthcare Policy and Management
  • Health Systems, Economic Evaluations, Quality of Life
  • Climate Change and Health Impacts
  • Global Public Health Policies and Epidemiology
  • Health disparities and outcomes
  • Head and Neck Cancer Studies
  • Trauma and Emergency Care Studies
  • Emergency and Acute Care Studies
  • Head and Neck Surgical Oncology
  • Sinusitis and nasal conditions
  • Injury Epidemiology and Prevention
  • Medical Malpractice and Liability Issues
  • Tracheal and airway disorders
  • Healthcare cost, quality, practices
  • Esophageal and GI Pathology
  • Salivary Gland Tumors Diagnosis and Treatment
  • Congenital Anomalies and Fetal Surgery
  • Patient-Provider Communication in Healthcare

Harvard University
2016-2025

Sisters of Mercy Health System
2016-2025

Massachusetts Eye and Ear Infirmary
2014-2024

Harvard Global Health Institute
2015-2024

University of Houston
2024

Charlottesville Medical Research
2024

Indianapolis Zoo
2024

West Los Angeles College
2024

Jackson College
2024

Kaiser Permanente Fontana Medical Center
2024

Christina Fitzmaurice Daniel Dicker Amanda Pain Hannah Hamavid Maziar Moradi‐Lakeh and 95 more Michael F MacIntyre Christine A. Allen Gillian M Hansen Rachel Woodbrook Charles Wolfe Randah R Hamadeh Ami R. Moore Andrea Werdecker Bradford D. Gessner Braden Te Ao Brian J. McMahon Chanté Karimkhani Chuanhua Yu Graham Cooke David C Schwebel David O. Carpenter David M. Pereira Denis Nash Dhruv S Kazi Diego De Leo Dietrich Plaß Kingsley Nnanna Ukwaja George Thurston Kim Yun Jin Edgar P. Simard Edward J Mills Eun‐Kee Park Ferrán Catalá-López Gabrielle deVeber Carolyn Gotay Gulfaraz Khan Hung Chak Ho Itamar S Santos Janet L Leasher Jasvinder A. Singh James Leigh Jost B. Jonas Juan Sanabria Justin Beardsley Kathryn H. Jacobsen Ken Takahashi Richard C. Franklin Luca Ronfani Marcella Montico Luigi Naldi Marcello Tonelli Johanna M. Geleijnse Max Petzold Mark G. Shrime Mustafa Z Younis Naohiro Yonemoto Nicholas J K Breitborde Paul Yip Farshad Pourmalek Paulo A. Lotufo Alireza Esteghamati Graeme J. Hankey Raghib Ali Raimundas Lunevičius Reza Malekzadeh Robert P Dellavalle Robert Weintraub Robyn Lucas Roderick J. Hay David Rojas‐Rueda Ronny Westerman Sadaf G Sepanlou Sandra Nolte Scott B. Patten Scott Weichenthal Semaw Ferede Abera Seyed-Mohammad Fereshtehnejad Ivy Shiue Tim Driscoll Tommi Vasankari Ubai Alsharif Vafa Rahimi‐Movaghar Vasily Vlassov Wagner Marcenes Alemayehu Mekonnen Yohannes Adama Melaku Yuichiro Yano Al Artaman Ismael Campos‐Nonato Jennifer H MacLachlan Ulrich Müeller Daniel Kim Matias Trillini Babak Eshrati Hywel C Williams Kenji Shibuya Rakhi Dandona Kinnari Murthy Benjamin C Cowie Azmeraw T. Amare

IMPORTANCECancer is among the leading causes of death worldwide.Current estimates cancer burden in individual countries and regions are necessary to inform local control strategies.OBJECTIVE To estimate mortality, incidence, years lived with disability (YLDs), life lost (YLLs), disability-adjusted life-years (DALYs) for 28 cancers 188 by sex from 1990 2013. EVIDENCE REVIEWThe general methodology Global Burden Disease (GBD) 2013 study was used.Cancer registries were source incidence data as...

10.1001/jamaoncol.2015.0735 article EN JAMA Oncology 2015-05-28

Traumatic brain injury (TBI)-the "silent epidemic"-contributes to worldwide death and disability more than any other traumatic insult. Yet, TBI incidence distribution across regions socioeconomic divides remain unknown. In an effort promote advocacy, understanding, targeted intervention, the authors sought quantify case burden of World Health Organization (WHO) Bank (WB) income groups.

10.3171/2017.10.jns17352 article EN cc-by-sa Journal of neurosurgery 2018-04-27

More than 2 billion people are unable to receive surgical care based on operating theatre density alone. The vision of the Lancet Commission Global Surgery is universal access safe, affordable and anaesthesia when needed. We aimed estimate number individuals worldwide without services as defined by Commission's vision.

10.1016/s2214-109x(15)70115-4 article EN cc-by The Lancet Global Health 2015-04-27

Meta-analysis-based calculation.Lumbar degenerative spine disease (DSD) is a common cause of disability, yet reliable measure its global burden does not exist. We sought to quantify the incidence lumbar DSD determine overall worldwide symptomatic across World Health Organization regions and Bank income groups.We used meta-analysis create single proportion cases in patients with low back pain (LBP). Using this information conjunction LBP rates, we calculated individuals who have (ie, their...

10.1177/2192568218770769 article EN cc-by-nc-nd Global Spine Journal 2018-04-24

BackgroundApproximately 150 million individuals worldwide face catastrophic expenditure each year from medical costs alone, and the non-medical of accessing care increase that number. The proportion this related to surgery is unknown. Because World Bank has proposed elimination impoverishment by 2030, effect surgical conditions on financial catastrophe should be quantified so any risk protection mechanisms can appropriately incorporate surgery.MethodsTo estimate global incidence due surgery,...

10.1016/s2214-109x(15)70085-9 article EN cc-by-nc-nd The Lancet Global Health 2015-04-01

Objective Both endoscopic sinus surgery (ESS) and biologic therapies have shown effectiveness for medically‐refractory chronic rhinosinusitis with nasal polyps (CRSwNP) without severe asthma. The objective was to evaluate cost‐effectiveness of dupilumab versus ESS patients CRSwNP. Study Design Cohort‐style Markov decision‐tree economic model a 36‐year time horizon. Methods A cohort 197 CRSwNP who underwent were compared matched 293 from the SINUS‐24 SINUS‐52 Phase 3 studies treatment 300 mg...

10.1002/lary.28648 article EN The Laryngoscope 2020-04-03

Clostridium difficile infection (CDI) is an important cause of morbidity and healthcare costs, characterized by high rates disease recurrence. The cost-effectiveness newer treatments for recurrent CDI has not been examined, yet would be to inform clinical practice. aim this study was analyze the cost effectiveness competing strategies CDI.We constructed a decision-analytic model comparing 4 treatment first-line in population with median age 65 years: metronidazole, vancomycin, fidaxomicin,...

10.1093/cid/ciu128 article EN Clinical Infectious Diseases 2014-03-31

Objective We aimed to describe the mortality burden and macroeconomic effects of head neck cancer as well delineate role surgical workforce in improving outcomes. Study Design Statistical economic analysis. Setting Research group. Subjects Methods conducted a statistical analysis on data from World Development Indicators 2016 Global Burden Disease study relationship between global mortality‐to‐incidence ratios. A value lost output model was used project cancer. Results Significant...

10.1177/0194599819897265 article EN Otolaryngology 2020-01-07

BackgroundThe way in which a government chooses to finance health intervention can affect the uptake of interventions and consequently extent gains. In addition gains, some policies such as public insure against catastrophic expenditures. We aimed evaluate financial risk protection benefits selected that could be publicly financed by Ethiopia.MethodsWe used extended cost-effectiveness analysis assess gains (deaths averted) afforded (cases poverty bundle nine (among many other) Government...

10.1016/s2214-109x(14)70346-8 article EN cc-by-nc-sa The Lancet Global Health 2015-04-14

Cleft lip and/or palate (CLP) is estimated to occur in 1 out of every 700 births, but for many people residing low- and middle-income countries this deformity may be repaired late life or not at all. This study aims analyze worldwide provider-perceived barriers the surgical repair CLP countries.From 2011 2014, Smile Train distributed a multiple-choice, voluntary survey healthcare providers identify areas need care worldwide. Data on provider-reported were aggregated by year, country, larger...

10.1097/scs.0000000000003038 article EN Journal of Craniofacial Surgery 2016-08-23

It is Ugandan governmental policy that all surgical care delivered at government hospitals in Uganda to be provided patients free of charge. In practice, however, frequent stock-outs and broken equipment require pay for large portions their out own pocket. The purpose this study was determine the financial impact on who undergo surgery a hospital Uganda.Every patient discharged from ward regional referral rural southwestern over 3-week period April 2016 asked participate. Patients agreed...

10.1371/journal.pone.0187293 article EN cc-by PLoS ONE 2017-10-31

IMPORTANCE Time-limited trials of intensive care are commonly used in patients perceived to have a poor prognosis.The optimal duration such is unknown.Factors as cancer diagnosis associated with clinician pessimism and may affect the decision limit independent patient's severity illness.OBJECTIVE To identify for short-term mortality critically ill cancer.DESIGN, SETTING, AND PARTICIPANTS Decision analysis using state-transition microsimulation model was performed simulate hospital course...

10.1001/jamaoncol.2015.3336 article EN JAMA Oncology 2015-10-15

Abstract Background In 2015, six indicators were proposed to evaluate global progress towards access safe, affordable and timely surgical anaesthesia care. Although some have been adopted as core health indicators, none has evaluated systematically. The aims of this study assess the availability, comparability utility present available data updated estimates. Methods Nationally representative compiled for all World Health Organization (WHO) member states from 2010 2016 through contacts with...

10.1002/bjs.11061 article EN cc-by British journal of surgery 2018-12-20

Background The WHO estimates a global shortage of 2.8 million physicians, with severe deficiencies especially in low and middle-income countries (LMIC). unequitable distribution physicians worldwide is further exacerbated by the migration from LMICs to high-income (HIC). This large-scale has numerous economic consequences which include increased mortality associated inadequate physician supply LMICs. Methods We estimate cost for due excess migration. To do so, we use concept value...

10.1136/bmjgh-2019-001535 article EN cc-by-nc BMJ Global Health 2020-01-01
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