A5041352515- Cerebrospinal fluid and hydrocephalus
- Global Health and Surgery
- Glioma Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Traumatic Brain Injury and Neurovascular Disturbances
- Fetal and Pediatric Neurological Disorders
- Spinal Fractures and Fixation Techniques
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Craniofacial Disorders and Treatments
- Venous Thromboembolism Diagnosis and Management
- Vascular Malformations Diagnosis and Treatment
- Meningioma and schwannoma management
- History of Medical Practice
- Cardiac, Anesthesia and Surgical Outcomes
- Diversity and Career in Medicine
- Cerebrovascular and Carotid Artery Diseases
- Head and Neck Surgical Oncology
- Neonatal and fetal brain pathology
- Spine and Intervertebral Disc Pathology
- Organ Donation and Transplantation
- Epilepsy research and treatment
- Surgical Simulation and Training
- Trauma and Emergency Care Studies
- Brain Metastases and Treatment
Vanderbilt University Medical Center
2015-2024
Neurological Surgery
2015-2024
Vanderbilt University
2014-2024
Monroe Carell Jr. Children's Hospital
2016-2024
Vanderbilt Health
2018-2024
Hospital for Sick Children
2020-2022
SickKids Foundation
2020-2021
Harvard University
2018-2020
University of Toronto
2020
Social Change and Development
2019-2020
Traumatic brain injury (TBI)-the "silent epidemic"-contributes to worldwide death and disability more than any other traumatic insult. Yet, TBI incidence distribution across regions socioeconomic divides remain unknown. In an effort promote advocacy, understanding, targeted intervention, the authors sought quantify case burden of World Health Organization (WHO) Bank (WB) income groups.
Worldwide disparities in the provision of surgical care result otherwise preventable disability and death. There is a growing need to quantify global burden neurosurgical disease specifically, workforce necessary meet this demand.
Background The development of new revascularization devices has improved recanalization rates and time, but not clinical outcomes. We report a prospectively collected experience with technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization. Methods 98 identified acute ischemic stroke patients 100 occluded cerebral vessels at six institutions were included in study. ADAPT was utilized all patients. Procedural data captured analysis....
The development of new revascularization devices has improved recanalization rates and time, but not clinical outcomes. We report a prospectively collected experience with technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization.98 identified acute ischemic stroke patients 100 occluded cerebral vessels at six institutions were included in study. ADAPT was utilized all patients. Procedural data captured analysis.The component alone...
Meta-analysis-based calculation.Lumbar degenerative spine disease (DSD) is a common cause of disability, yet reliable measure its global burden does not exist. We sought to quantify the incidence lumbar DSD determine overall worldwide symptomatic across World Health Organization regions and Bank income groups.We used meta-analysis create single proportion cases in patients with low back pain (LBP). Using this information conjunction LBP rates, we calculated individuals who have (ie, their...
Background The development of new revascularization devices has improved recanalization rates and time but not clinical outcomes. We report our initial results with a technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization. Methods A retrospective evaluation prospectively captured database 37 patients at six institutions was performed on where ADAPT utilized. data represent experience this technique. Results alone successful in 28...
The development of new revascularization devices has improved recanalization rates and time but not clinical outcomes. We report our initial results with a technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization.A retrospective evaluation prospectively captured database 37 patients at six institutions was performed on where ADAPT utilized. data represent experience this technique.The alone successful in 28 (75%) cases although had...
BACKGROUND: Stent-assisted coiling with 2 stents in a Y configuration is technique for complex wide-neck bifurcation aneurysms. OBJECTIVE: We sought to provide long-term clinical and angiographic outcomes Y-stent coiling, which are not currently established. METHODS: Seven centers provided deidentified, retrospective data on all consecutive patients who underwent stent-assisted an intracranial aneurysm configuration. RESULTS: Forty-five treatment by coiling. Their mean age was 57.9 years....
OBJECTIVE Antiepileptic drugs (AEDs) are often administered prophylactically following brain tumor resection. With conflicting evidence and unestablished guidelines, however, the nature of this practice among surgeons is unknown. METHODS On November 24, 2015, a REDCap (Research Electronic Database Capture) survey was sent to members AANS/CNS Section on Tumors query patterns. RESULTS Responses were received from 144 individuals, including 18.8% board-certified neurosurgeons surveyed (across...
OBJECTIVE Central nervous system (CNS) infections cause significant morbidity and mortality often require neurosurgical intervention for proper diagnosis treatment. However, neither the international burden of CNS infection, nor current capacity workforce to treat these diseases is well characterized. The objective this study was elucidate global incidence surgically relevant highlighting geographic areas targeted improvement in capacity. METHODS A systematic literature review meta-analysis...
Background: Clinical trials of anti-Aβ monoclonal antibodies in Alzheimer disease (AD) infer target engagement from Aβ positron emission tomography (PET) and/or fluid biomarkers such as cerebrospinal (CSF) Aβ42/40.However, these measure deposits indirectly incompletely.In contrast, postmortem neuropathologic assessments allow direct investigation treatment effects on brain and many other pathologic features.Methods: From a clinical trial dominantly inherited AD, we measured...
Hydrocephalus (HC) is a heterogenous disease characterized by alterations in cerebrospinal fluid (CSF) dynamics that may cause increased intracranial pressure. HC component of wide array genetic syndromes as well secondary consequence brain injury (intraventricular hemorrhage (IVH), infection, etc.) can present across the age spectrum, highlighting phenotypic heterogeneity disease. Surgical treatments include ventricular shunting and endoscopic third ventriculostomy with or without choroid...
Object Dandy-Walker complex (DWC) is a continuum of congenital anomalies comprising malformation (DWM), variant (DWV), Blake pouch cyst, and mega cisterna magna (MCM). Hydrocephalus variably associated with each these, DWC-associated hydrocephalus has mostly been treated by shunting, often 2-compartment shunting. There are few reports management endoscopic third ventriculostomy (ETV). This study the largest series DWC or DWM-associated ETV, first report treatment combined ETV choroid plexus...
OBJECTIVE The presence and capability of existing pediatric neurosurgical care worldwide is unknown. objective this study was to solicit the expertise specialists quantify geographic representation neurosurgeons, access specialist care, equipment training needs globally. METHODS A mixed-question survey sent surgeon members several international general surgical societies via a web-based platform. Respondents answered questions on 5 categories: demographics training, hospital practice...