A5062345574- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Cerebral Venous Sinus Thrombosis
- Neurosurgical Procedures and Complications
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- Neurological Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Moyamoya disease diagnosis and treatment
- Vascular Procedures and Complications
- Cardiovascular Health and Disease Prevention
- Blood Coagulation and Thrombosis Mechanisms
- Medical Imaging and Analysis
- Clinical practice guidelines implementation
- Meningioma and schwannoma management
- Retinal and Optic Conditions
- Spinal Fractures and Fixation Techniques
- Cardiac Structural Anomalies and Repair
Prisma Health
2019-2025
University of South Carolina
2024
Greenville Memorial Hospital
2023
Proteogenomics Research Institute for Systems Medicine
2021
Medical University of South Carolina
2011-2020
Baptist Medical Center Jacksonville
2018
University of Tennessee Health Science Center
2018
University of Utah
2018
Mallinckrodt (United States)
2018
Rush University Medical Center
2018
Background The development of new revascularization devices has improved recanalization rates and time, but not clinical outcomes. We report a prospectively collected experience with technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization. Methods 98 identified acute ischemic stroke patients 100 occluded cerebral vessels at six institutions were included in study. ADAPT was utilized all patients. Procedural data captured analysis....
The development of new revascularization devices has improved recanalization rates and time, but not clinical outcomes. We report a prospectively collected experience with technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization.98 identified acute ischemic stroke patients 100 occluded cerebral vessels at six institutions were included in study. ADAPT was utilized all patients. Procedural data captured analysis.The component alone...
Background The development of new revascularization devices has improved recanalization rates and time but not clinical outcomes. We report our initial results with a technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization. Methods A retrospective evaluation prospectively captured database 37 patients at six institutions was performed on where ADAPT utilized. data represent experience this technique. Results alone successful in 28...
The development of new revascularization devices has improved recanalization rates and time but not clinical outcomes. We report our initial results with a technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization.A retrospective evaluation prospectively captured database 37 patients at six institutions was performed on where ADAPT utilized. data represent experience this technique.The alone successful in 28 (75%) cases although had...
Objective Flexible large lumen aspiration catheters and stent retrievers have recently become available in the USA for revascularization of vessel occlusions presenting within context acute ischemic stroke (AIS). We describe a multicenter experience using combined retrieval technique thrombectomy. Design A retrospective analysis to identify patients receiving manual treatment AIS between August 2012 April 2013 at six high volume centers was conducted. Outcome variables, including...
BACKGROUND: Stent-assisted coiling with 2 stents in a Y configuration is technique for complex wide-neck bifurcation aneurysms. OBJECTIVE: We sought to provide long-term clinical and angiographic outcomes Y-stent coiling, which are not currently established. METHODS: Seven centers provided deidentified, retrospective data on all consecutive patients who underwent stent-assisted an intracranial aneurysm configuration. RESULTS: Forty-five treatment by coiling. Their mean age was 57.9 years....
Introduction The direct aspiration first pass technique (ADAPT) has been introduced as a simple and fast method for achieving good angiographic clinical outcomes using large bore catheters the treatment of acute ischemic stroke (AIS). We present single center's long term experience with ADAPT. Methods Retrospective analysis database was gathered on patients undergoing thrombectomy ADAPT at center. Specific parameters captured included age, gender, National Institutes Health Stroke Scale...
Emergent carotid artery stenting plus mechanical thrombectomy is an effective treatment for acute ischemic stroke patients with tandem occlusion of the anterior circulation. However, there limited data supporting safety this approach in treated prior intravenous thrombolysis (IVT). We aimed to investigate emergent stenting-mechanical patient population IVT—We assessed because atherosclerotic that were from multicenter observational Thrombectomy Tandem Lesions registry. Patients divided into...
The treatment of acute ischemic stroke is traditionally centered on time criteria, although recent evidence suggests that physiologic neuroimaging may be useful. In a multicenter study we evaluated the use CT perfusion, regardless from symptom onset, in patients selected for intra-arterial stroke.Three medical centers retrospectively assessed with National Institute Health Stroke Scale ≥ 8, onset. perfusion maps were qualitatively assessed. Patients defined salvageable penumbra underwent...
The endovascular stent-assisted coiling approach for the treatment of cerebral aneurysms is evolving rapidly with availability new stent devices. It remains unknown how each type affects safety and efficacy stent-coiling procedure.This study compared outcomes using Neuroform (NEU), Enterprise (EP), Low-profile Visualized Intraluminal Support (LVIS) stents. Patient characteristics, details angiographic results Raymond-Roy grade scale (RRGS), procedural complications were analyzed in our...
Abstract BACKGROUND Aneurysm recurrence after coiling has been associated with aneurysm growth, (re)hemorrhage, and a greater need for follow-up. The second-generation HydroCoil Embolic System (HES; MicroVention, Inc) consists of platinum core integrated hydrogel was developed to reduce through enhancing packing density healing within the aneurysm. OBJECTIVE To compare between HES bare coil (BPC) in new-generation Hydrogel Endovascular Treatment Trial (HEAT). METHODS HEAT is randomized,...
Traditional treatment in acute ischemic stroke is based on time criteria when administering intravenous and intra-arterial therapies. However, recent evidence suggests that image-based may be useful for selecting patients interventions. The use of CT perfusion (CTP)-based criteria, regardless from symptom onset, patient selection was assessed.Patients with who presented to the emergency department at Medical University South Carolina a National Institute Health Stroke Scale score ≥ 8, were...
This study retrospectively compared the clinical and angiographic outcomes of treating cerebral aneurysms with Neuroform (NEU), Enterprise (EP), Low-profile Visualized Intraluminal Support (LVIS/LVIS Jr) stents.We conducted a retrospective analysis procedural database. All aneurysm procedures using any three types self-expanding nitinol stents (NEU, EP LVIS/LVIS were included. Intra-procedure complications, post-procedure results (Raymond-Roy grade scale, RRGS) analyzed retrospectively. A...
Background The effect of the five positive randomized controlled trials on thrombectomy practices and procedural volume has yet to be defined. Further, few studies have attempted define modern in terms selection criteria devices used. Methods A 21 question survey Society Neurointerventional Surgery (SNIS) physicians was administered using SurveyMonkey website, addressing current as well changes from before January 1, 2015 months after this date. Results total 78 responses were obtained...
Clot density (Hounsfield units, HU) and perviousness (post-contrast increase in the HU of clot) are thought to be associated with clot composition. We evaluate whether these imaging characteristics were angiographic outcomes aspiration stent retriever thrombectomy COMPASS: a trial versus as first-line approach for large vessel occlusion.Clot measured by two independent operators who blind all final clinical outcomes. The association Thrombolysis In Cerebral Infarction (TICI) scale after...
Socioeconomic status influences health outcomes, including cerebrovascular diseases. Patients from socioeconomically deprived areas may present with more severe conditions due to delayed access care. This study evaluates the association between neighborhood-level deprivation, measured by Area Deprivation Index (ADI), and treatment of ruptured intracranial aneurysms (RIAs) compared unruptured (UIAs) across multiple centers. retrospective cohort analyzed data 4517 patients treated for cerebral...
Background and purpose Revascularization of acute ischemic stroke from a large vessel occlusion continues to be challenge with current thrombectomy devices. The the SPEED study was report safety effectiveness Penumbra 054 Reperfusion Catheter System in revascularizing occlusions. Methods In this retrospective multicenter study, data were collected patients angiographic evidence treated device as intended primary therapy. Clinical outcome 90-day follow-up results compared those Pivotal trial....
Newer flat panel angiographic detector (FD) systems have the capability to generate parenchymal blood volume (PBV) maps. The ability these maps in suite has potential markedly expedite triage and treatment of patients with acute ischemic stroke. present study compares FP-PBV cerebral (CBV) derived using standard dynamic CT perfusion (CTP) a population stroke.56 cerebrovascular disease at two participating institutions prospectively underwent both CTP imaging followed by FD-PBV (syngo Neuro...
Introduction Dissecting and wide-necked aneurysms that incorporate a large portion of the parent artery can be challenging to treat with currently available devices. This study reports three cases treated new hybrid stent design incorporates smaller cell size more pliable than current generation stents results in some flow diversion characteristics. Methods In all cases, use low-profile visible intraluminal support (LVIS) device conjunction coil embolization was determined provide best...
Background Idiopathic intracranial hypertension (IIH) is a syndrome defined by elevated without radiographic evidence of mass lesion in the brain. Dural venous sinus stenosis has been increasingly recognized as treatable cause, and dural stenting (DVSS) performed. Methods A 5 year single-center retrospective analysis consecutive patients undergoing DVSS for medically refractory IIH. Results There were 43 with mean imaging follow-up 6.5 months clinical period 13.5 months. was performed first...
Venous sinus stenting is a popular treatment strategy for patients with high venous pressure gradients across site of outflow obstruction. Little known about the effect anesthesia on measurements.To compare manometry performed in under general and while awake.A prospective database was accessed to retrospectively identify who had undergone stenting. Pressure were compared between those underwent awake before anesthesia.Thirty both recordings identified. measurements highly variable but...