Julien Labreuche

ORCID: 0000-0002-3384-0423
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Stroke Rehabilitation and Recovery
  • Venous Thromboembolism Diagnosis and Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Intracranial Aneurysms: Treatment and Complications
  • Peripheral Artery Disease Management
  • Lipoproteins and Cardiovascular Health
  • Cardiovascular Health and Disease Prevention
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Nosocomial Infections in ICU
  • Liver Disease Diagnosis and Treatment
  • COVID-19 Clinical Research Studies
  • Blood Pressure and Hypertension Studies
  • Respiratory Support and Mechanisms
  • Alcohol Consumption and Health Effects
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac Imaging and Diagnostics
  • Food Allergy and Anaphylaxis Research
  • Sepsis Diagnosis and Treatment
  • Infective Endocarditis Diagnosis and Management
  • Long-Term Effects of COVID-19
  • Liver Disease and Transplantation
  • Pneumonia and Respiratory Infections
  • Atrial Fibrillation Management and Outcomes

Centre Hospitalier Universitaire de Lille
2016-2025

Université de Lille
2016-2025

Evaluation des technologies de santé et des pratiques médicales
2015-2025

Unité de Technologies Chimiques et Biologiques pour la Santé
2020-2025

Technologies pour la Santé
2017-2024

Université Lille Nord de France
2014-2024

Hôpital Gui de Chauliac
2017-2024

French Clinical Research Infrastructure Network
2022-2024

Hôpital Claude Huriez
2017-2024

Inserm
2013-2023

Objective The COVID‐19 pandemic is rapidly spreading worldwide, notably in Europe and North America where obesity highly prevalent. relation between severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) has not been fully documented. Methods This retrospective cohort study analyzed the relationship clinical characteristics, including BMI, requirement for invasive mechanical ventilation (IMV) 124 consecutive patients admitted intensive care SARS‐CoV‐2 a single French center. Results...

10.1002/oby.22831 article EN Obesity 2020-04-09

factor VIII ◼ pulmonary embolism thrombosis von Willebrand W e report a case series of patients with coronavirus disease 2019 (CO-VID-19) (PE) in our institution.Lille University Hospital is the tertiary care center for North France, second greatest French region population density (189 people per 1 km 2 ), also considered metabolic area high number overweight patients.The study was approved by institutional data protection authority Lille Hospital.Among 107 first consecutive confirmed...

10.1161/circulationaha.120.047430 article EN mit Circulation 2020-04-24

<h3>Importance</h3> The benefits of endovascular revascularization using the contact aspiration technique vs stent retriever in patients with acute ischemic stroke remain uncertain because lack evidence from randomized trials. <h3>Objective</h3> To compare efficacy and adverse events standard as a first-line treatment for successful among large vessel occlusion. <h3>Design, Setting, Participants</h3> Contact Aspiration Stent Retriever Successful Revascularization (ASTER) study was...

10.1001/jama.2017.9644 article EN JAMA 2017-08-01

Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during first 3 months after a transient ischemic attack (TIA) minor stroke. The TIAregistry.org project designed describe contemporary profile, etiologic factors, outcomes in patients with TIA who receive care health systems now offer urgent evaluation by specialists.We recruited had within previous 7 days. Sites were selected if they dedicated TIA. We 1-year...

10.1056/nejmoa1412981 article EN New England Journal of Medicine 2016-04-20

The use of intensive lipid-lowering therapy by means statin medications is recommended after transient ischemic attack (TIA) and stroke atherosclerotic origin. target level for low-density lipoprotein (LDL) cholesterol to reduce cardiovascular events has not been well studied.

10.1056/nejmoa1910355 article EN New England Journal of Medicine 2019-11-18

Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired is low. We aimed to determine relationship between pneumonia, as compared influenza pneumonia or no viral infection, and VA-LRTI.Multicenter retrospective European cohort performed in 36 ICUs. All adult receiving invasive mechanical ventilation > 48 h were eligible if they had: at ICU admission. VA-LRTI,...

10.1007/s00134-020-06323-9 article EN other-oa Intensive Care Medicine 2021-01-02

After a transient ischemic attack (TIA) or minor stroke, the long-term risk of stroke and other vascular events is not well known. In this follow-up to report on 1-year outcomes from registry TIA clinics in 21 countries that enrolled 4789 patients with 2009 through 2011, we examined 5-year events.

10.1056/nejmoa1802712 article EN New England Journal of Medicine 2018-05-16

Background and Purpose— Although successful reperfusion is usually defined as a modified Thrombolysis in Cerebral Infarction (mTICI) 2B or 3 at the end of procedure, studies have shown that mTICI patients had poorer functional outcomes than TICI patients. An 2C category has been recently introduced for with near-complete perfusion except slow flow few distal cortical vessels presence small emboli after mechanical thrombectomy. The purpose this study was to evaluate difference outcome between...

10.1161/strokeaha.118.020700 article EN Stroke 2018-04-06

Understanding the mechanisms of outcome according to time frame can help optimize therapeutic development in severe alcoholic hepatitis. We assessed short-term and long-term survival hepatitis based on baseline disease severity, extent improvement, influence alcohol relapse, their interaction. Data consumption were prospectively recorded 398 patients treated with corticosteroids short term (from corticosteroid initiation 6 months) long months maximum follow-up time). Cumulative incidence...

10.1002/hep.29240 article EN Hepatology 2017-05-01

<h3>Importance</h3> Mechanical thrombectomy using a stent retriever or contact aspiration is widely used for treatment of patients with acute ischemic stroke due to anterior circulation large vessel occlusion, but the additional benefit combining uncertain. <h3>Objective</h3> To determine whether mechanical occlusion initial and combined results in better final angiographic outcome than standard alone. <h3>Design, Setting, Participants</h3> This trial was multicenter randomized, open-label,...

10.1001/jama.2021.13827 article EN JAMA 2021-09-28
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