A5100752902- Pneumonia and Respiratory Infections
- Nosocomial Infections in ICU
- Respiratory Support and Mechanisms
- Respiratory viral infections research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sepsis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Cystic Fibrosis Research Advances
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Emergency and Acute Care Studies
- Long-Term Effects of COVID-19
- Respiratory and Cough-Related Research
- Antibiotic Resistance in Bacteria
- Pediatric health and respiratory diseases
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Neonatal Respiratory Health Research
- Inhalation and Respiratory Drug Delivery
- Influenza Virus Research Studies
- Airway Management and Intubation Techniques
- Antimicrobial Resistance in Staphylococcus
- Tracheal and airway disorders
- Pleural and Pulmonary Diseases
- Asthma and respiratory diseases
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2016-2025
Universitat de Barcelona
2016-2025
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2016-2025
Hospital Clínic de Barcelona
2016-2025
Instituto de Salud Carlos III
2016-2025
Centre for Biomedical Network Research on Rare Diseases
2017-2025
Hospital Universitari de Vic
2024
Institució Catalana de Recerca i Estudis Avançats
2020-2024
Fundació Clínic per a la Recerca Biomèdica
2016-2024
State Library of Ohio
2024
priate starting point for consultation by specialists.Substantial overlap exists among the patients whom these guidelines address and those discussed in recently published health care-associated pneumonia (HCAP).Pneumonia nonambulatory residents of nursing homes other long-term care facilities epidemiologically mirrors hospital-acquired should be treated according to HCAP guidelines.However, certain whose conditions are included designation better served management accordance with CAP...
"Medical Section pf the American Lung Association: Guidelines for Initial Management of Adults with Community-acquired Pneumonia: Diagnosis, Assessment Severity, and Antimicrobial Therapy." Review Respiratory Disease, 148(5), pp. 1418–1426
The most recent European guidelines and task force reports on hospital-acquired pneumonia (HAP) ventilator-associated (VAP) were published almost 10 years ago. Since then, further randomised clinical trials of HAP VAP have been conducted new information has become available. Studies epidemiology, diagnosis, empiric treatment, response to antibiotics or forms antibiotic administration disease prevention changed old paradigms. In addition, important differences between approaches in Europe the...
Seventy-eight (24%) episodes of nosocomial pneumonia (NP) were detected in 322 consecutive mechanically ventilated patients admitted to a 1,000-bed teaching hospital from April 1987 through May 1988 assess the incidence, risk, and prognosis factors NP acquired during mechanical ventilation (MV). The risk for developing MV studied using both univariate multivariate statistical techniques. Multivariate analysis selected following variables significantly associated with higher...
The duration of spontaneous breathing trials before extubation has been set at 2 h in research studies, but the optimal is not known. We conducted a prospective, multicenter study involving 526 ventilator-supported patients considered ready for weaning, to compare clinical outcomes with target durations 30 and 120 min. Of 270 256 30- 120-min trial groups, respectively, 237 (87.8%) 216 (84.8%), completed without distress were extubated (p = 0.32); 32 (13.5%) 29 (13.4%), these required...
In order to confirm that re-intubation can be a risk factor of nosocomial pneumonia in mechanically ventilated patients, case-control study was performed. Forty consecutive patients needing were selected as cases. Each case paired with matched control for the previous duration mechanical ventilation (+/- 2 d). Nineteen (47%) cases developed after compared 4 (10%) controls (odds ratio [OR] = 8.5; 95% confidence interval [CI] 1.7 105.9; p 0.0007). After adjusting age, sex, and presence prior...
<h3>BACKGROUND</h3> A study was undertaken to assess the diagnostic value of different clinical criteria and impact microbiological testing on accuracy diagnosis suspected ventilator associated pneumonia (VAP). <h3>METHODS</h3> Twenty five deceased mechanically ventilated patients were studied prospectively. Immediately after death, multiple bilateral lung biopsy specimens (16 specimens/patient) obtained for histological examination quantitative cultures. The presence both positive cultures...
IMPORTANCEIn patients with severe community-acquired pneumonia, treatment failure is associated excessive inflammatory response and worse outcomes.Corticosteroids may modulate cytokine release in these patients, but the benefit of this adjunctive therapy remains controversial.OBJECTIVE To assess effect corticosteroids communityacquired pneumonia high response.DESIGN, SETTING, AND PARTICIPANTS Multicenter, randomized, double-blind, placebo-controlled trial conducted 3 Spanish teaching...
All episodes of ventilator-associated pneumonia (VAP) caused by Staphylococcus aureus were prospectively analyzed for a 30-mo period. Methicillin-sensitive S. (MSSA) was isolated in 38 and methicillin-resistant (MRSA) 11 others. The two groups similar regarding sex, severity underlying diseases, prior surgery, presence renal failure, diabetes, cardiopathy, coma. MRSA-infected persons more likely to have received steroids before developing infection (relative risk [RR] = 3.45, 95% confidence...
The aim of the present study was to identify risk factors for community-acquired pneumonia (CAP), with special emphasis on modifiable and those applicable general population. A population-based, case–control conducted, a target population 859,033 inhabitants aged >14 yrs. total 1,336 patients confirmed CAP were matched control subjects by age, sex primary centre over 1 yr. In univariate analysis, outstanding passive smoking in never-smokers >65 yrs, heavy alcohol intake, contact pets,...
To describe variation in antibiotic prescribing for acute cough contrasting European settings and the impact on recovery.Cross sectional observational study with clinicians from 14 primary care research networks 13 countries who recorded symptoms presentation management. Patients followed up 28 days patient diaries.Primary care.Adults a new or worsening clinical suggestive of lower respiratory tract infection.Prescribing antibiotics by total symptom severity scores over time.3402 patients...
There is a need for clear definition of exacerbations used in clinical trials patients with bronchiectasis. An expert conference was convened to develop consensus an exacerbation use research.A systematic review definitions from January 2000 until December 2015 and involving adults bronchiectasis conducted. A Delphi process followed by round-table meeting experts organised reach definition. These came Europe (representing the European Multicentre Bronchiectasis Research Collaboration), North...
<h3>Background</h3> The distribution of the microbial aetiology and mortality community-acquired pneumonia (CAP) was investigated in relation to clinical setting severity scores (pneumonia index (PSI) confusion, blood urea nitrogen, respiratory rate, pressure, age (CURB-65)). <h3>Methods</h3> 3523 patients with CAP were included (15% outpatients, 85% inpatients). (PSI, CURB-65) relative different aetiologies across analysed. <h3>Results</h3> established 1463 (42%), whom 257 died (7%)....
Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired is low. We aimed to determine relationship between pneumonia, as compared influenza pneumonia or no viral infection, and VA-LRTI.Multicenter retrospective European cohort performed in 36 ICUs. All adult receiving invasive mechanical ventilation > 48 h were eligible if they had: at ICU admission. VA-LRTI,...