A5002717967- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Hepatitis B Virus Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Diseases and Immunity
- Renal Transplantation Outcomes and Treatments
- Hepatitis Viruses Studies and Epidemiology
- Transplantation: Methods and Outcomes
- Organ Donation and Transplantation
- Alcohol Consumption and Health Effects
- Helicobacter pylori-related gastroenterology studies
- Parasitic infections in humans and animals
- Inflammatory Bowel Disease
- Systemic Lupus Erythematosus Research
- Digestive system and related health
- Parasitic Infections and Diagnostics
- Pneumocystis jirovecii pneumonia detection and treatment
- Congenital Anomalies and Fetal Surgery
- Neuroendocrine Tumor Research Advances
- HIV/AIDS drug development and treatment
- Autoimmune and Inflammatory Disorders
- Genetic and Kidney Cyst Diseases
- MRI in cancer diagnosis
University of Liège
2016-2025
Centre Hospitalier Universitaire de Liège
2016-2025
Ghent University Hospital
2024
Institut National de Recherche en Santé Publique
2024
Jackson and Tull (United States)
2024
Centre Hospitalier Universitaire de Grenoble
2022
Hospital Universitario Austral
2022
Austral University
2022
Paris-Est Sup
2022
Université Paris-Est Créteil
2022
Keratin 7 positive (K7+) cells are considered to be activated in case of impaired hepatocyte replication. Their exact role and their interaction with hepatocytes macrophages also implicated liver regeneration remain poorly characterized humans. The aim this study is evaluate hepatocyte, K7+ macrophage populations severe alcohol-related steatohepatitis (sASH) link them injury patients' outcomes. Immunohistochemical morphometric studies for total cells, (CD68+ cells), proliferative (Ki67+...
Chronic hepatitis B (CHB) patients with advanced fibrosis are often not considered for treatment peginterferon (PEG-IFN) because IFN therapy may precipitate immunological flares, potentially inducing hepatic decompensation. We investigated the efficacy and safety of treating e antigen (HBeAg)–positive CHB 52 weeks PEG-IFN-α-2b (100μg weekly) alone or in combination lamivudine (100 mg daily). Seventy (Ishak score 4–6) 169 without fibrosis, all compensated liver disease, participated study....
Patients with acromegaly are reported to be at risk of developing adenomatous colonic polyps, which considered preneoplastic lesions. This assumption is, however, usually drawn from results obtained in rather small series patients or without a control group. We, therefore, undertook prospective colonoscopic and pathological study comprising 103 acromegalic 138 nonacromegalic subjects referred for irritable bowel syndrome. The prevalence polyps was significantly increased compared that (22.3%...
Summary Background Stopping nucleos(t)ide analogues (NA) after hepatitis B e antigen ( HB eAg) seroconversion is associated with high relapse rates in Asian patients, but data Caucasian cohorts are scarce. Clinical course, outcomes and immunological aspects of chronic infections differ substantially between distinct ethnicities. Aim The aim this study was to determine rates, factors predicting clinical analogue cessation a large, predominantly cohort patients analogue‐induced eAg...
Hepatitis B virus (HBV)-hepatitis delta (HDV) coinfection is the most severe form of chronic viral hepatitis, but factors that determine disease progression and severity are incompletely characterised. This long-term follow-up study aims to identify risk for liver-related outcomes. In this multicentre national cohort study, data from admission until last visit between 2001 2023 was retrospectively collected 162 HBV-HDV coinfected patients. The inclusion criteria were HBsAg or HBV DNA...
Guillain-Barré syndrome (GBS) is often triggered by a preceding bacterial or viral infection. Occasionally, it has been observed in association with acute hepatitis A, B and C, three cases have previously described India which GBS was associated E. A molecular mimicry mechanism supposed to be involved the pathogenesis of infectious agents, although nature shared epitopes not characterized most instances, including that case hepatotropic viruses. We report following E European individual. The...
Abstract Background Results of donation after circulatory death (DCD) liver transplantation are impaired by graft loss, resulting mainly from non-anastomotic biliary stricture. Donor age is a risk factor in deceased donor transplantation, and particularly DCD transplantation. At the authors' institute, not an absolute exclusion criterion for discarding grafts, donors receive comfort therapy before withdrawal, cold ischaemia minimized. Methods All consecutive transplantations performed 2003...
The renewed interest in donation after cardio-circulatory death (DCD) started the 1990s following limited success of transplant community to expand brain-death (DBD) organ supply and request potential DCD families. Since then, procurement transplantation activities have rapidly expanded, particularly for non-vital organs, like kidneys. In liver (LT), donors are a valuable source that helps decrease mortality rate on waiting lists increase availability organs despite higher risk early graft...
Summary Aim : To evaluate the efficacy of early interferon α ‐2b in non‐post‐transfusion acute hepatitis C virus: a prospective study with historical comparison. Patients Group A: 28 patients prospectively treated for virus daily regimen 5 million units 2 months. B: series 16 untreated virus. Results There was no significant difference between two groups regard to gender, age, icterus, alanine aminotransferase, or genotypes. In group B, spontaneously resolved three (19%) (follow‐up 1–7...
Although hepatocellular carcinoma (HCC) has become a recognized indication for liver transplantation, the rules governing priority and access to waiting list are not well defined. Patient- tumor-related variables were evaluated in 226 patients listed primarily HCC Belgium, region where allocation system is patient-driven, being given sicker patients, based on Child-Turcotte-Pugh (CTP) score. Intention-to-treat posttransplantation survival rates at 4 years 56.5 66%, respectively, overall...
Epidemiological data on hepatitis delta virus (HDV) infection in Belgium are lacking. A multicenter questionnaire-based registry HDV was collated between March 1, 2008 and February 28, 2009. It consisted of patients coinfected with B (HBV) HDV. The samples were compared to those a concurrent HBV infection. Prospective HBV-HDV coinfection collected. Active replication is defined as HBeAg positivity or DNA > 2,000 IU/ml. Forty-four from 15 centers registered. comparison 29 infected (registered...
Weight gain poses a rising concern post-liver transplantation (LT), and metabolic dysfunction–associated steatotic liver disease might impair graft health. The timing is crucial when considering bariatric surgery (BS) in population with or transplantation. BS can be considered for post-LT weight gain, although the evidence limited long-term outcome still uncertain. We conducted national retrospective analysis 5 Belgian transplant centers included 25 patients an LT followed by procedure. A...
Peripheral as well central mechanisms are thought to play a role in cluster headache pathogenesis. We have studied recovery curves of the R2 component blink reflex after conditioning by supraorbital or index finger stimuli 10 episodic (CH) patients during period and healthy controls. There was no significant change threshold, latency area CH patients. After paired stimuli, recovered more rapidly on symptomatic side. stimulations, rapid both non-symptomatic sides compared Naloxone (0.4 mg)...