A5051332860- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Diet, Metabolism, and Disease
- Alcohol Consumption and Health Effects
- Systemic Lupus Erythematosus Research
- Hepatitis Viruses Studies and Epidemiology
- Liver Diseases and Immunity
- Hematological disorders and diagnostics
- Diet and metabolism studies
- Microscopic Colitis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- HIV/AIDS drug development and treatment
- Immunodeficiency and Autoimmune Disorders
- Drug-Induced Hepatotoxicity and Protection
- Renal Diseases and Glomerulopathies
- Pancreatitis Pathology and Treatment
- Pesticide Exposure and Toxicity
- Retinoids in leukemia and cellular processes
- Chronic Lymphocytic Leukemia Research
- Liver physiology and pathology
- Hidradenitis Suppurativa and Treatments
- Intraperitoneal and Appendiceal Malignancies
- Acupuncture Treatment Research Studies
Hôpitaux Iris Sud
2013-2025
IS practice
2021
Cliniques Universitaires Saint-Luc
1991
Clinique Saint Pierre
1984
Keratin 7 positive (K7+) cells are considered to be activated in case of impaired hepatocyte replication. Their exact role and their interaction with hepatocytes macrophages also implicated liver regeneration remain poorly characterized humans. The aim this study is evaluate hepatocyte, K7+ macrophage populations severe alcohol-related steatohepatitis (sASH) link them injury patients' outcomes. Immunohistochemical morphometric studies for total cells, (CD68+ cells), proliferative (Ki67+...
Recently, concerns were raised of high rates HCC recurrence in patients treated with direct-acting antivirals (DAA) for hepatitis C infection. We investigated the occurrence and within 6 months after treatment DAA or without pegylated interferon (PEG-IFN) real life. This is a retrospective, multicenter cohort trial, executed 15 hospitals distributed across Belgium. Populations matched based on fibrosis score (Metavir F3-F4). Patients Child-Pugh ≥ B excluded. In total, 567 included, whom 77...
Hepatitis B virus (HBV)-hepatitis delta (HDV) coinfection is the most severe form of chronic viral hepatitis, but factors that determine disease progression and severity are incompletely characterised. This long-term follow-up study aims to identify risk for liver-related outcomes. In this multicentre national cohort study, data from admission until last visit between 2001 2023 was retrospectively collected 162 HBV-HDV coinfected patients. The inclusion criteria were HBsAg or HBV DNA...
We have seen two patients with watery diarrhea whose work-up revealed a collagenous infiltration beneath the rectal epithelium. Within year, symptoms disappeared in both. Repeated biopsy disappearance of collagen layer. Collagenous colitis may thus present as transient condition.
Immunosuppressive drugs may prevent or partially reverse progression of renal AA-amyloidosis, a rare complication Crohn's disease, often fatal due to failure.The clinical, biological and pathological data 16 patients treated since 1976 were reviewed. Serum amyloid A was determined in surviving patients.The median age the (13 men) 23·5 years (range 16-69). At disease onset, Montreal phenotypes similar reported data. Out 15 with insufficiency, 8 developed nephrotic syndrome 7 low grade...
Introduction Nationwide studies comparing patients with hepatitis B and C virus (HBV HCV) infections are mandatory for assessing changes in epidemiology. Aim The aim of this study was to compare epidemiological data initial management newly diagnosed persistent HBV (HBsAg positive) or HCV (detectable RNA) infection Belgium. Patients methods Data were extracted from two Belgian observational databases. Results A total 655 (387 268 included. Compared patients, younger, more frequently men,...
Introduction Hepatitis C virus (HCV) is a major global health issue and successful treatment has been associated with reduction of risk all-cause mortality. Advancements have made in HCV through the use interferon-free regimens. Most trials conducted genotype (GT) 1 data for regimens GT4 patients are limited. The aim this study was to evaluate safety efficacy sofosbuvir plus simeprevir real-world cohort advanced fibrosis. Patients Methods Eighty-seven treatment-naïve or –Interferon (IFN)...
Summary. The standard treatment for patients with chronic hepatitis C is a 6–12‐month combination therapy interferon alpha and ribavirin. Induction could result in faster early decline of the virus (HCV) load better response rate. Naive chronically infected HCV ( n = 454) were randomized into two arms to receive either induction 2b 5 million units (MU) subcutaneously (s.c.) daily during period 8 weeks (arm A); or MU s.c. three times week (TIW) B). After 8, both was 3 TIW total 12 months. In...
No data have been reported yet on treatment outcome in persons who inject drugs (PWID) infected with hepatitis C virus treated boceprevir or telaprevir combination peginterferon (Peg IFN) and ribavirin (RBV). Additionally, there are concerns about the safety of some subgroups patients (HCV). In a cohort HCV genotype 1 Belgium, due to IV drug use was analyzed compared no history substance use. The study population consisted 179 patients: 78 PWID 101 controls (n = 79) 100) additional Peg IFN...