Chrysanthi Papagiannaki
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Moyamoya disease diagnosis and treatment
- Stroke Rehabilitation and Recovery
- Aortic aneurysm repair treatments
- Peripheral Artery Disease Management
- Vascular Malformations and Hemangiomas
- Spinal Fractures and Fixation Techniques
- Aortic Disease and Treatment Approaches
- Meningioma and schwannoma management
- Cerebral Venous Sinus Thrombosis
- Neurosurgical Procedures and Complications
- Vascular anomalies and interventions
- Central Venous Catheters and Hemodialysis
- Cardiac, Anesthesia and Surgical Outcomes
- Blood Coagulation and Thrombosis Mechanisms
- Oropharyngeal Anatomy and Pathologies
- Coronary Interventions and Diagnostics
- Neurological Disease Mechanisms and Treatments
- Cervical and Thoracic Myelopathy
Université de Rouen Normandie
2016-2025
Centre Hospitalier Universitaire de Rouen
2015-2025
Hôpital Gui de Chauliac
2024
Helsinki University Hospital
2023
University of Basel
2023
University of Bern
2023
University Hospital of Bern
2023
University of Helsinki
2023
Université de Reims Champagne-Ardenne
2023
Hôpital Maison Blanche
2023
The use of thrombectomy in patients with acute stroke and a large infarct unrestricted size has not been well studied.
Background and purpose Flow diversion is an innovative increasingly used endovascular treatment for intracranial aneurysms. Its initial evaluation with the first devices available showed good efficacy of this variable safety results. The Direction Endoluminal Device (FRED) has a specific design was evaluated in single-arm, multicenter, prospective, Good Clinical Practice study: SAFE (Safety Analysis FRED Embolic device aneurysm treatment). This analysis reports clinical results at 1 year...
<h3>BACKGROUND AND PURPOSE:</h3> The safety and efficacy of WEB flow disruption have been analyzed in small, retrospective series. object this study was to evaluate the a large, multicenter, prospectively collected population. <h3>MATERIALS METHODS:</h3> Data from all patients treated with WEB-DL device between June 2011 October 2013 11 French neurointerventional centers were retrospectively analyzed. Complications occurring during after treatment as well morbidity mortality at 1 month....
Curative transvenous embolization is an emerging strategy for treatment of cerebral arteriovenous malformations (AVMs).To assess contemporary outcomes as a stand-alone therapy AVMs.We prospectively followed 40 patients with 41 AVMs who underwent endovascular between January 2008 and 2015. Patient demographics, AVM characteristics, techniques used, angiographic results, clinical outcomes, complications were assessed independently.Thirty-eight (92.6%) anatomically cured. The mean patient age...
<h3>BACKGROUND AND PURPOSE:</h3> Endovascular treatment with the flow-disrupter Woven EndoBridge aneurysm embolization system (WEB) is an innovative for wide-neck bifurcation aneurysms. Prospective, multicenter studies have shown high safety of this technique. Stability occlusion in long-term follow-up has been rarely studied. Moreover "compression" phenomenon reported and seems to be associated poor anatomic results. This prospective, single-center series analyzes efficacy WEB device...
Background and hypothesis There is no consensus on the optimal endovascular management of extracranial internal carotid artery steno-occlusive lesion in patients with acute ischemic stroke due to tandem occlusion. We hypothesized that intracranial mechanical thrombectomy plus emergent stenting (and at least one antiplatelet therapy) superior alone Study design TITAN an investigator-initiated, multicenter, prospective, randomized, open-label, blinded-endpoint (PROBE) study. Eligibility...
<h3>BACKGROUND AND PURPOSE:</h3> The susceptibility vessel sign on MR imaging has been reported to indicate acute occlusion from erythrocyte-rich thrombus. purpose of this study was evaluate the influence seen before treatment clinical outcome after mechanical thrombectomy for anterior circulation stroke. <h3>MATERIALS METHODS:</h3> We retrospectively included 73 consecutive patients who were treated stroke by December 2009 September 2013. Each patient underwent thrombectomy. presence...
Background and purpose Flow diverters are increasingly used for the treatment of intracranial aneurysms. Evaluation first devices available clinical use showed high efficacy this although safety results were worse compared with coiling or balloon-assisted coiling. The S afety Efficacy A nalysis F RED E mbolic Device in Aneurysm Treatment (SAFE) trial is a single-arm, multicenter, prospective study conducted to precisely analyze FRED Jr devices. Methods Unruptured recanalized aneurysms...
Procedural complications in thrombectomy for large vessel occlusions of the anterior circulation are not well described. We investigated incidence, risk factors, and clinical implications daily practice.We used data from ongoing prospective multicenter observational Endovascular Treatment Ischemic Stroke Registry France. The present study is a retrospective analysis 4029 stroke patients with treated between January 2015 May 2020 18 centers. systematically collected procedural data, incidence...
Background Studies have suggested that collateral status modifies the effect of successful reperfusion on functional outcome after endovascular therapy (EVT). We aimed to assess association between and EVT outcomes investigate whether modified outcomes. Methods used data from ongoing, prospective, multicenter Endovascular Treatment in Ischemic Stroke (ETIS) Registry. Collaterals were graded according American Society Interventional Therapeutic Neuroradiology/Society Radiology (ASITN/SIR)...
BACKGROUND: Transvenous embolization (TVE) is a new treatment of brain arteriovenous malformations (AVMs). The safety and efficacy TVE have not been compared with transarterial (TAE). primary hypothesis this trial was that would increase the proportion AVM occlusion from 40% to 80%. METHODS: TATAM (Transvenous Approach for Treatment Cerebral AVMs) an investigator-initiated, multicenter, prospective, phase 2, open-label, controlled randomized comparing versus TAE alone (1:1). Patients...
Patients treated with acute carotid stenting (CAS) may have higher odds of a favorable outcome than those without CAS during thrombectomy in tandem occlusions. Antiplatelet therapy is associated to avoid stent thrombosis, which occurs around 20% patients and negatively impacts outcomes. In this study we compared two antiplatelet strategies occlusion strokes intracranial clinical practice.The Endovascular Treatment Ischemic Stroke Registry an ongoing prospective observational involving 21...
The Medina Embolization Device (MED) is a new concept device that combines the design of detachable coil and one an intrasaccular flow disruption device.To evaluate feasibility, safety, 6- to 9-mo effectiveness this for treatment intracranial wide-necked aneurysms.Twelve patients (10 females, mean age = 56 yr) with 13 aneurysms (3 ruptured; 10 unruptured) were treated by means MED from January 2015 October 2015. In 15% cases, MEDs used in standalone fashion; 85% additional regular coils...
Studies comparing endovascular stroke treatment using mechanical thrombectomy (MT) with or without prior IV tissue plasminogen activator (tPa) have included only 30% of internal carotid artery terminus occlusions (ICA-O), a known predictor recanalization failure tPa. To carry out retrospective multicenter analysis prospectively collected data consecutive patients to investigate the impact intravenous thrombolysis on ICA-O by treated MT alone bridging therapy (BT). Patients BT were...
There is to date limited evidence that revascularization strategies are associated with improved functional outcome in children acute ischemic stroke (AIS).To report clinical outcomes and provide estimates of strategy safety efficacy profiles intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) AIS.The KidClot multicenter nationwide cohort study retrospectively collected data (neonates excluded) AIS recanalization between January 1, 2015, May 31, 2018. Data analysis was...
Background Endovascular treatment (EVT) for basilar artery occlusions (BAO) is associated with a higher rate of futile recanalization compared anterior circulation procedures. We aimed to identify the incidence and predictors poor clinical outcome despite successful reperfusion in current practice. Methods used data from ETIS (Endovascular Treatment Ischemic Stroke) registry, prospective multicenter observational registry stroke treated EVT France. Patients undergoing acute BAO January 2014...
Background: Whether bridging therapy (intravenous thrombolysis [IVT] followed by mechanical thrombectomy) is superior to IVT alone in minor stroke with large vessel occlusion unknown. Perfusion imaging may identify subsets of occlusion–related patients distinct response therapy. Methods: We conducted a multicenter international observational study consecutive IVT-treated (National Institutes Health Stroke Scale score ≤5) who had an anterior circulation and perfusion performed before IVT,...