Mahmood Mirza

ORCID: 0000-0002-7721-4774
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Venous Thromboembolism Diagnosis and Management
  • Peripheral Artery Disease Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Intracranial Aneurysms: Treatment and Complications
  • Stroke Rehabilitation and Recovery
  • Neurological Disorders and Treatments
  • Trauma Management and Diagnosis
  • Vascular Procedures and Complications
  • Airway Management and Intubation Techniques
  • Surgical Simulation and Training
  • Clinical practice guidelines implementation
  • Neurological Disease Mechanisms and Treatments
  • Dental Radiography and Imaging
  • Cardiac pacing and defibrillation studies
  • Renal function and acid-base balance
  • Advanced X-ray and CT Imaging
  • Atrial Fibrillation Management and Outcomes
  • Case Reports on Hematomas
  • Central Venous Catheters and Hemodialysis
  • Cardiac Arrhythmias and Treatments
  • Respiratory Support and Mechanisms
  • Nausea and vomiting management

Johnson & Johnson (United States)
2025

Johnson & Johnson (Ireland)
2021-2023

Galway Clinic
2021

Deccan College of Medical Sciences
2017

Baylis Medical (Canada)
2010

Background Despite significant advancements in the procedural efficacy of mechanical thrombectomy patients with ischemic stroke recent years, there still remains a portion population that does not achieve good recanalization. The reasons for this may be varied. We hypothesized static friction between clot and vessel, or catheter wall might contribute to difficulty removing clot. Objective To determine if is relationship composition resistance sliding (friction) which removal. Methods As can...

10.1136/neurintsurg-2016-012721 article EN Journal of NeuroInterventional Surgery 2017-01-02

Aim: According to the results of MASTRO I living systematic review and meta-analysis, use EmboTrap Revascularization ® Device in treatment acute ischemic stroke (AIS) higher rates good functional outcomes (90-day modified Rankin Scale [mRS] 0–2) compared with Trevo Retriever or Solitaire™ Device. The aim this analysis was assess potential economic impact achieving improved for three commonly used stent retrievers (SRs) AIS. Methods: An model short-term long-term costs, representing a...

10.57264/cer-2024-0216 article EN cc-by-nc-nd Journal of Comparative Effectiveness Research 2025-02-17

Studies comparing endovascular stroke treatment using mechanical thrombectomy (MT) with or without prior IV tissue plasminogen activator (tPa) have included only 30% of internal carotid artery terminus occlusions (ICA-O), a known predictor recanalization failure tPa. To carry out retrospective multicenter analysis prospectively collected data consecutive patients to investigate the impact intravenous thrombolysis on ICA-O by treated MT alone bridging therapy (BT). Patients BT were...

10.1136/neurintsurg-2017-013398 article EN Journal of NeuroInterventional Surgery 2017-11-16

ABSTRACT BACKGROUND AND PURPOSE The susceptibility vessel sign (SVS) on magnetic resonance imaging (MRI) is related to thrombus location, composition, and size in acute stroke. No previous study has determined its inter‐MRI scanner variability. We aimed compare the diagnostic accuracy in‐vitro of four different MRI scanners for characterization histologic composition. METHODS Thirty‐five manufactured thrombi analogs composition that were histologically categorized as fibrin‐dominant, mixed,...

10.1111/jon.12464 article EN Journal of Neuroimaging 2017-08-03

MR imaging quantitative T2* mapping, which provides information about thrombus composition and specifically the red blood cell content, may be obtained in setting of acute ischemic stroke before treatment. This could useful to adapt endovascular strategy. We aimed analyze content vitro thrombi relation thrombus-T2* relaxation time.Thirty-five analogs different compositions were scanned with an mapping sequence. Two radiologists, blinded composition, measured time twice at interval 2 weeks....

10.3174/ajnr.a5938 article EN cc-by American Journal of Neuroradiology 2019-01-01

<h3>BACKGROUND AND PURPOSE:</h3> About 20% of patients with acute ischemic stroke due to large-artery occlusion do not achieve recanalization mechanical thrombectomy. We aimed determine whether the speed retrieval stent retriever influences efficacy in removing different clot types. <h3>MATERIALS METHODS:</h3> Sixty thrombectomies were performed using an vitro pulsatile cerebrovascular circulation model controlled pressure and flow rate. Experiments dichotomized into fast slow a wedging...

10.3174/ajnr.a6559 article EN cc-by American Journal of Neuroradiology 2020-05-14

The objective of this study was to demonstrate the safety and efficacy a new transseptal needle design with radiofrequency (RF) tip combined ease use configuration.RF puncture enter left heart, RF wire-catheter system is successful technique in patients complex access using standard needle.The (NRG™ Transseptal Needle; Baylis Medical, Montreal, Canada) designed for percutaneous heart. Eight pigs underwent transvenous cardiac catheterization baseline intracardiac electrograms right atrial...

10.1002/ccd.22600 article EN Catheterization and Cardiovascular Interventions 2010-04-29

Introduction: Tortuosity of Internal carotid artery impact on achieving first pass in mechanical thrombectomy has been previously described. Here, we investigate the association middle cerebral artery(MCA) tortuosity radiographic and functional outcome. Methods: The Analysis Revascularization Ischemic Stroke with EmboTrap II was utilized to identify patients anterior circulation stroke. MCA calculated using Inflection Count Metric(ICM) by two blinded readers angiographical/clinical outcomes....

10.1161/str.55.suppl_1.tp188 article EN Stroke 2024-02-01

Mechanical thrombectomy (MT) for acute ischemic stroke (AIS) relies on efficient tracking of aspiration catheters through complex vascular anatomies. Differences in catheter design lead to variation performance which may only become apparent after use patients. We developed an

10.1177/15910199241278993 article EN Interventional Neuroradiology 2024-08-30

<h3>Introduction</h3> Neuro-interventional models are often used to develop, test, and compare devices techniques. Their implications depend greatly on accurate modeling of the vessel diameters, which may be impacted by ethnic variations. <h3>Aim Study</h3> To determine if size differences exist between European Chinese populations. <h3>Methods</h3> A systematic review literature in PubMed database was performed identify studies reporting diameters obtained through validated imaging healthy...

10.1136/jnis-2023-esmint.205 article EN Abstracts 2023-08-21

<h3>Introduction</h3> Research into occlusion factors has substantially increased in recent years, including imaging, flow patterns, clot composition, histology, immunohistochemistry, and biomechanical properties. However, integrating them clinical practice to identify a challenging prior retrieval is not well established. <h3>Methods</h3> A modified DELPHI technique was used before during CLOT SUMMIT 7.0, which included experts thrombectomy research from different specialties. Panelists...

10.1136/jnis-2023-snis.236 article EN SNIS 19th annual meeting electronic poster abstracts 2023-07-01
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