<h3>BACKGROUND AND PURPOSE:</h3> Arteriovenous malformations are an important etiology of hemorrhagic stroke. However, current imaging modalities and risk do not provide insights into individual AVM hemodynamics its role in pathophysiology. The aims this study to determine whether intracranial 4D flow MR can arteriovenous malformation independent the Spetzler-Martin grade report changes observed during staged embolization. <h3>MATERIALS METHODS:</h3> Intracranial 3D blood was assessed 20...

Purpose To use four‐dimensional (4D)‐flow MRI for the comprehensive in vivo analysis of hemodynamics and its relationship to size morphology different intracranial aneurysms (IA). We hypothesize that IA groups, defined by morphology, exhibit velocity fields, wall shear stress, vorticity. Materials Methods The 4D‐flow (spatial resolution = 0.99–1.8 × 0.78–1.46 1.2–1.4 mm 3 , temporal 44–48 ms) was performed 19 IAs (18 patients, age 55.4 ± 13.8 years) with saccular (n 16) fusiform 3) sizes...

<h3>BACKGROUND AND PURPOSE:</h3> Contrast enhancement of intracranial atherosclerotic plaques has recently been investigated using high field and resolution MR imaging as a risk factor in the development ischemic stroke. We studied reliability conventional at 1.5T evaluating intraplaque its relationship with acute cerebrovascular presentations patients severe disease. <h3>MATERIALS METHODS:</h3> retrospectively identified analyzed 19 22 high-grade disease (&gt;70% stenosis) vessels...

The authors undertook this study to assess the safety and efficacy of Onyx embolization in treatment intracranial arteriovenous malformations (AVMs) pediatric patients.All AVM cases performed consecutively at a single children's hospital over 5-year period were collected evaluated.Twenty-five patients (mean age 10.5 years) underwent total 38 procedures. An aggregate 56 pedicles embolized 1.47 per session). Spetzler-Martin grade was determined all cases. resulted complete obliteration 3 (12%)...

Background Admission neutrophil-lymphocyte ratio (NLR) is significantly correlated to clinical outcomes in acute ischemic stroke (AIS). We investigated follow-up NLR and temporal changes after endovascular thrombectomy (EVT) with respect successful revascularization, outcomes, symptomatic intracranial hemorrhage (sICH) mortality. Methods Retrospective analysis of EVT for anterior circulation emergent LVO was performed both admission (NLR1) 3–7 day (NLR2) laboratory data. Patient...

The current gold standard for imaging intracranial AVMs involves catheter-based techniques, namely cerebral digital subtraction angiography (DSA). However, DSA presents some procedural risks to the patient. Unfortunately, AVM patients usually undergo multiple exams throughout their diagnostic and therapeutic course, significantly increasing risk exposure. As such, high-quality noninvasive is desired. We hypothesize that 4D radial acquisition contrast-enhanced MRA approximates vascular...

BACKGROUND: Although Onyx is widely used to embolize vascular lesions in adults, the safety and efficacy of this liquid embolic agent for use children are not well studied. OBJECTIVE: To report our experience using pediatric patients a variety cranial spinal tumors determine its procedural complication rates, types, clinical consequences highlight indications principles embolization patients. METHODS: All cases performed consecutively by neuroendovascular services at 2 institutions over...

<h3>BACKGROUND AND PURPOSE:</h3> The role of intracranial hemodynamics in the pathophysiology and risk stratification brain AVMs remains poorly understood. purpose this study was to assess influence Spetzler-Martin grade, clinical history, factors on vascular flow tissue perfusion cerebral AVMs. <h3>MATERIALS METHODS:</h3> 4D MR imaging performed 17 patients with Peak velocity blood were quantified AVM feeding contralateral arteries, draining veins, straight sinus. Regional ratios (CBF, CBV,...

<h3>BACKGROUND AND PURPOSE:</h3> Pathological changes in the intracranial aneurysm wall may lead to increases its permeability; however clinical significance of such has not been explored. The purpose this pilot study was quantify permeability (<i>K</i>^trans, V_L) contrast agent as a measure rupture risk and compare these parameters against other established measures risk. We hypothesized <i>K</i>^trans would be associated with defined by various anatomic,...

Adoption of endovascular treatment (EVT) and other advances in aneurysm care have shifted practice patterns cerebral over the past 2 decades US. The objective this study was to determine whether resulting trends volumes, outcomes, complications matured general or continue evolve.

Background Cerebral arteriovenous malformations (AVMs) are pathological connections between arteries and veins. Dual‐ venc 4D flow MRI, an extended MRI method with improved velocity dynamic range, provides time‐resolved 3D cerebral hemodynamics. Purpose To optimize dual‐ imaging parameters for AVM; to assess the relationship spatial resolution, acceleration, quantification accuracy; introduce apply distribution network graph (FDNG) paradigm storing analyzing complex neurovascular data. Study...

<h3>BACKGROUND AND PURPOSE:</h3> 3D high-resolution black-blood MRI or MR vessel wall imaging allows evaluation of the intracranial arterial and extraluminal pathology. We investigated diagnostic accuracy reliability for intraluminal detection large-vessel occlusions. <h3>MATERIALS METHODS:</h3> retrospectively identified patients with occlusions, confirmed by CTA DSA, who also underwent nonenhanced contrast-enhanced T1 sampling perfection application-optimized contrasts using different flip...

We report the first use of Onyx in embolization spinal tumors 2 cases aggressive vertebral hemangioma. In both cases, provided effective preoperative tumor devascularization after initial prolonged particulate with Embospheres made little overall impact. enables a more rapid and visible than particles is less technically demanding traditional liquid embolic agents, such as n-butyl cyanoacrylate.

To evaluate the ability to predict presence of dysthyroid optic neuropathy (DON) using computed tomography assessment soft-tissue and clinical features.A retrospective consecutive case series patients with thyroid-related orbitopathy.One hundred eighty-nine orbits from 99 were evaluated. Statistically significant predictors DON on univariate analysis included a difference in intraocular pressure primary gaze upgaze (P = .02), lagophthalmos .04), inflammation as measured by VISA (vision,...

Complex hemodynamics in cerebral arteriovenous malformations (AVM) are thought to play a key role their pathophysiology. We applied 4D flow magnetic resonance imaging (MRI) for the detailed evaluation of AVM function at baseline and investigate impact staged embolization on patient with Spetzler‐Martin grade III AVM. The underwent three procedures resulting &gt;50% nidal casting obliteration several fistulae. MRI demonstrated highly complex 3D revealed intricate arterial feeding, large...

<h3>BACKGROUND AND PURPOSE:</h3> Autosomal dominant polycystic kidney disease is associated with an increased risk of intracranial aneurysms. Our purpose was to assess whether there during aneurysm coiling and clipping. <h3>MATERIALS METHODS:</h3> Data were obtained from the National Inpatient Sample (2000–2011). All subjects had unruptured clipped or coiled divided into (<i>n</i> = 189) control 3555) groups. Primary end points included in-hospital mortality, length stay, total hospital...

Objective To investigate the impact of coil design on distribution mass in a controlled vitro experiment. A secondary objective was to study relationship between angiographic occlusion, packing density and uniformity. Methods Seven silicon side wall aneurysm models were embolized each arm with different under fluoroscopic guidance. Packing calculations scoring occlusion made. The embedded epoxy sectioned through neck dome. sections imaged processed derive fractional surface area material...