A5073112941- Vascular Malformations Diagnosis and Treatment
- Vascular Malformations and Hemangiomas
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Spinal Fractures and Fixation Techniques
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Spine and Intervertebral Disc Pathology
- Radiation Dose and Imaging
- Vascular Tumors and Angiosarcomas
- Management of metastatic bone disease
- Central Venous Catheters and Hemodialysis
- Cerebral Venous Sinus Thrombosis
- Aortic aneurysm repair treatments
- Soft tissue tumor case studies
- Neurofibromatosis and Schwannoma Cases
- Spinal Dysraphism and Malformations
- Neurosurgical Procedures and Complications
- Renal and Vascular Pathologies
- Meningioma and schwannoma management
- Vascular Procedures and Complications
- Aortic Disease and Treatment Approaches
- Tumors and Oncological Cases
- Spinal Cord Injury Research
Vancouver General Hospital
2014-2024
University of British Columbia
2015-2024
Vancouver Biotech (Canada)
2024
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Hôpital de l'Enfant-Jésus
2022
Université Laval
2022
British Columbia Children's Hospital
2006-2021
Novartis (Canada)
2018
University of British Columbia Hospital
2017
Children's & Women's Health Centre of British Columbia
2006-2012
Biomarkers of acute human spinal cord injury (SCI) could provide a more objective measure damage and better predictor neurological outcome than current standardized assessments. In SCI, there is growing interest in establishing biomarkers from cerebrospinal fluid (CSF) magnetic resonance imaging (MRI). Here, we compared the ability CSF MRI to classify severity predict recovery cohort cervical SCI patients. samples scans 36 patients were examined. From taken 24 h post-injury, concentrations...
Within vascular anomalies, malformations are those present at birth that grow with the patient and exhibit abnormal dilated channels lined by mature endothelium. Vascular tumors, other group of demonstrate endothelial hypercellularity. further divided into low-flow varieties (capillary, venous, lymphatic malformations) high-flow (arteriovenous malformation fistula). All a predictable clinical patterns vary in severity rate progression. The interventional radiologist must incorporate this...
<h3>Purpose</h3> The purpose of this investigation is to describe the clinical, imaging, histologic and flow dynamic characteristics orbital cavernous haemangioma. <h3>Methods</h3> In clinicopathologic series, clinical features were obtained from patient records. All imaging studies reviewed. specimens reviewed with haematoxylin eosin, 10 subject a staining protocol including: Movat Pantachrome, periodic acid Schiff, D2-40, CD31, GLUT-1, Ki-67, vascular endothelial growth factor receptor 1...
OBJECTIVE. The spinal instability neoplastic scale (SINS) is a new classification system for tumor-related instability. SINS may prove to be valuable tool radiologists communicate with oncologists and surgeons in standardized evidence-based manner. objective of this study was determine the inter- intraobserver reliability validity among radiologists.
Background: Cystic lymphatic vascular malformations are benign lesions that can cause disfigurement and functional impairment. Complete surgical resection is often difficult, clinical recurrence common. Sclerotherapy has been used as an alternative to excision. OK-432 a lyophilized mixture of Streptococcus pyogenes benzylpenicillin which, when injected into lesion, shown significant ability reduce its size or obliterate it completely. Methods: The authors report series 12 patients treated in...
In acute traumatic cervical spinal cord injury (SCI) patients, we sought to characterize how objective MRI measures of change during the first 3 week post-injury. Six scans each were planned in 19 SCI patients within Length edema, maximum compression, canal compromise, and presence length hematoma measured. edema increased 48 h after SCI, followed by a gradual decrease weeks injury. This was predominantly seen more severe grades SCI. Hematoma all AIS-A B patients. study demonstrates dynamic...
To determine the causes of lacrimal gland inflammation based on histopathology and systemic evaluation.This is a retrospective case series study. From University British Columbia Orbit Clinic between January 1976 December 2008, we reviewed medical records 60 patients who presented with inflammatory features (i.e., erythema, edema, or tenderness) in which diagnoses were not possible clinically imaging alone. As was our routine practice, all these underwent biopsy before starting any...
Optic pathway gliomas (OPGs) are present in 20% of children with neurofibromatosis 1 (NF1) but less frequently observed adults. Our goal was to determine the natural history OPGs and adults NF1.We analyzed features other intracranial lesions on 1775 head MRI scans 562 unselected NF1 collected between 2003 2015. 52 (9.3%) patients this study had an OPG diagnosed their MRI. The median age at first scan 12.7 years. Of patients, intraorbital optic nerves were affected 29 (56%), prechiasmatic 32...
To evaluate the ability to predict presence of dysthyroid optic neuropathy (DON) using computed tomography assessment soft-tissue and clinical features.A retrospective consecutive case series patients with thyroid-related orbitopathy.One hundred eighty-nine orbits from 99 were evaluated. Statistically significant predictors DON on univariate analysis included a difference in intraocular pressure primary gaze upgaze (P = .02), lagophthalmos .04), inflammation as measured by VISA (vision,...
<h3>BACKGROUND AND PURPOSE:</h3> Brain parenchymal hyperdensity on postthrombectomy CT in patients with acute stroke can be due to hemorrhage and/or contrast staining. We aimed determine whether iodine concentration within contrast-stained parenchyma compared an internal reference the superior sagittal sinus dual-energy could predict subsequent intracerebral hemorrhage. <h3>MATERIALS METHODS:</h3> Seventy-one small infarct cores (ASPECTS ≥ 7) and good endovascular recanalization (modified...
Balo concentric sclerosis is a rare demyelinating disease. Pathognomonic features have been previously described. Diffusion-wighted imaging findings not described in sclerosis. We describe the diffusion-weighted 45-year-old lady with Diffusion-weighted offers insight into possible pathophysiology of this
Percutaneous sclerotherapy is the preferred method of treatment for VMs (venous malformations). However, protocols vary, and research on most effective sclerosant conflicting. Additionally, there limited knowledge effect volume outcome. This study aims to determine outcomes complications image-guided with respect volume. Towards this, a 10-year retrospective chart review was conducted patients treated at Vascular Anomalies Clinic British Columbia Children's Hospital. Thirty-four were which...
We describe a minimally invasive endovascular approach to treat an arteriovenous fistula of the scalp. performed direct puncture lesion through patient's scalp for liquid embolic agent injection along with external compression superficial temporal artery perform "manual pressure-cooker technique." The combination these techniques resulted in excellent clinical and radiographic outcome.