A5048624747- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Meningioma and schwannoma management
- Renal and Vascular Pathologies
- Abdominal Trauma and Injuries
- Aortic aneurysm repair treatments
- Bacterial Infections and Vaccines
- Aortic Disease and Treatment Approaches
- Advanced MRI Techniques and Applications
- Anesthesia and Neurotoxicity Research
- Cerebral Venous Sinus Thrombosis
- Cardiac, Anesthesia and Surgical Outcomes
- Biosensors and Analytical Detection
- Cerebrovascular and genetic disorders
- Listeria monocytogenes in Food Safety
Inserm
2019-2024
Aix-Marseille Université
2019-2024
Hôpital de la Timone
2018-2024
Assistance Publique Hôpitaux de Marseille
2019-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2024
Centre de Résonance Magnétique Biologique et Médicale
2023
Centre National de la Recherche Scientifique
2020-2023
FHU Neurovasc
2021-2022
Institut de Psychiatrie et Neurosciences de Paris
2021-2022
Université Paris Cité
2021-2022
Since December 2019, a novel coronavirus, also called severe acute respiratory syndrome CoV-2 (SARS-CoV-2), emerged in Wuhan, China, and caused pandemic disease (COVID-19). Respiratory impairment is the most common symptom patients with confirmed COVID-19; however, neurologic symptoms were documented approximately 36%, including headache, disturbed consciousness, paresthesia.1 The virus can take different pathways to involve CNS: one way through hematogenous or lymphatic route another via...
Neurointerventionists lack guidelines for the use of antithrombotic therapies in their clinical practice; consequently, there is likely to be significant heterogeneity between centers. Through a nationwide survey, we aimed obtain an exhaustive cross-sectional overview neurointerventional procedures France.In April 2021, French surgery centers were invited participate 51-question survey disseminated through active trainee-led research collaborative network (the JENI-RC).All 40 answered...
Background and Purpose Patients with acute ischemic stroke, proximal vessel occlusion a large core at presentation are commonly not considered for mechanical thrombectomy (MT). We tested the hypothesis that in patients baseline infarct cores, identification of remaining penumbral tissue using perfusion imaging would translate to better outcomes after MT.<br/>Methods This was multicenter, retrospective, lab adjudicated, cohort study adult occlusion, volume (diffusion weighted ≥70 mL),...
There is to date limited evidence that revascularization strategies are associated with improved functional outcome in children acute ischemic stroke (AIS).To report clinical outcomes and provide estimates of strategy safety efficacy profiles intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) AIS.The KidClot multicenter nationwide cohort study retrospectively collected data (neonates excluded) AIS recanalization between January 1, 2015, May 31, 2018. Data analysis was...
<b><i>Introduction:</i></b> Patients with chronic kidney disease (CKD) have an increased risk of stroke, and CKD seems associated worse outcome after a stroke. The main objective our study <i>RISOTTO</i> was to evaluate the influence acute injury (AKI) on clinical mortality ischemic stroke patients thrombolysis and/or thrombectomy. <b><i>Methods:</i></b> This multicenter cohort included in phase due large artery occlusion managed by...
Balloon-assisted mechanical angioplasty for cerebral vasospasm following aneurysmal subarachnoid hemorrhage (aSAH) has a number of limitations, including transient occlusion the spastic blood vessel. Comaneci is an FDA-approved device temporary coil embolization assistance which recently also been approved treatment distal symptomatic refractory vasospasm. We aimed to report feasibility, efficacy and safety our experience with (up second segment arteries) aSAH.This retrospective analysis...
Rescue intracranial stenting (RIS) can be used in refractory large vessel occlusion (LVO) after mechanical thrombectomy (MT). We aimed to assess the safety and efficacy of RIS versus a propensity matched sample patients with persistent LVO.
Individualized patient selection for mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS) and large core (LIC) at baseline is an unmet need. We tested the hypothesis that assessing functional relevance of both infarcted hypoperfused brain tissue would improve framework LIC MT.We performed a multicenter, retrospective study adults (ischemic volume >70 mL on MRI diffusion-weighted imaging) perfusion treated MT or best medical management (BMM). Primary outcome was 3-month...
The dramatic clinical improvement offered by mechanical thrombectomy raised questions about the relevance of prior intravenous thrombolysis in large-vessel occlusion strokes. Hence, studying susceptibility and its dependence on thrombus composition is crucial. We used an observational proteomic study whole thrombi retrieved to identify factors associated with fibrin content fibrinolytic activity (FA). In 104 stroke patients, proteome was established mass spectrometry coupled liquid...
The occurrence of persistent intra-device filling (BOSS 1, using the Bicêtre Occlusion Scale Score (BOSS)) in aneurysms treated with a Woven Endobridge (WEB) device is infrequent based on angiographic follow-up. To date, three monocentric case series were published studying BOSS 1 cases. Through multicenter retrospective study, we aimed to report incidence, and risk factors intra-WEB filling.We reached out European academic centers that treat patients WEB devices requested de-identified data...
<h3>BACKGROUND AND PURPOSE:</h3> Noninvasive angiography is commonly used to assess the outcome of surgical or endovascular treatment intracranial aneurysms in clinical series randomized trials. We sought whether a standardized 3-grade classification system could be reliably compare CTA and MRA results both treatments. <h3>MATERIALS METHODS:</h3> An electronic portfolio composed CTAs 30 clipped MRAs coiled was independently evaluated by 24 raters diverse experience training backgrounds....
Pediatric nontraumatic intracerebral hemorrhage accounts for half of stroke in children. Early diagnostic the causative underlying lesion is first step toward prevention hemorrhagic recurrence. We aimed to investigate performance arterial spin labeling sequence (ASL) acute phase etiological workup detection an arteriovenous shunt (AVS: including malformation and fistula), most frequent cause pediatric hemorrhage. Children with a between 2011 2019 enrolled prospective registry were...
In this study, we report our local experience of type A aortic dissections in patients with cerebral malperfusion treated carotid stenting before or after surgery, and present a systematic literature review on these either (CS) surgery (AS) alone (ACS). We center for brain hemodynamic injury origin caused by dissection since 2018, was conducted PubMed articles published from 1990 to 2021. Out 5307 articles, 19 could be included total 80 analyzed: 9 center, 29 case reports, 51 two...