A5088229615- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Moyamoya disease diagnosis and treatment
- COVID-19 Clinical Research Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac tumors and thrombi
- Peripheral Artery Disease Management
- Stroke Rehabilitation and Recovery
- Cardiac Imaging and Diagnostics
- Soft Robotics and Applications
- Neurological Complications and Syndromes
- Vascular Procedures and Complications
- Climate Change and Health Impacts
- Trauma and Emergency Care Studies
- Retinal and Optic Conditions
- Fluid Dynamics and Mixing
- Neurosurgical Procedures and Complications
- Aortic aneurysm repair treatments
- COVID-19 and healthcare impacts
- Anesthesia and Pain Management
Université de Strasbourg
2018-2023
Hôpitaux Universitaires de Strasbourg
2017-2022
Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona
2020
Hôpital Civil, Strasbourg
2019
Hôpital d'Hautepierre
2017
Background and purpose To date, no study has attempted to quantify the impact of COVID‐19 outbreak on incidence treatment acute stroke. Methods This was a retrospective review stroke pathway parameters in all three units Alsace region during first month (1–31 March 2020), using similar period from 2019 as comparator. A secondary detailed analysis alerts unit admissions performed centre with largest case volume. Results Compared same 2019, 2020 there were 39.6% fewer 33.3% revascularization...
There are very few published data on the patency of carotid stents implanted during thrombectomies for tandem lesions in anterior circulation. We aimed to communicate our experience stenting acute setting with systematic follow-up stent and discuss predictors clinical repercussions delayed thrombosis.We performed a retrospective study stroke single center between January 2009 April 2018. Patient files were reviewed extract patient characteristics, procedural details, imaging studies,...
Acute ischemic stroke and large vessel occlusion can be concurrent with the coronavirus disease 2019 (COVID-19) infection. Outcomes after mechanical thrombectomy (MT) for in patients COVID-19 are substantially unknown. Our aim was to study early outcomes MT COVID-19.Multicenter, European, cohort involving 34 centers France, Italy, Spain, Belgium. Data were collected between March 1, 2020 May 5, 2020. Consecutive laboratory-confirmed cases occlusion, who treated MT, included. Primary...
Periprocedural antithrombotic treatment is a key determinant for the risk-benefit balance of emergent carotid artery stenting (eCAS) during stroke thrombectomy. We aimed to assess safety and efficacy three types treatment.Retrospective review prospectively collected endovascular databases in four comprehensive centers, including consecutive cases eCAS tandem lesion strokes between January 2019 July 2021. During this period, each center applied one periprocedural protocols: (a) two centers...
Initial clinical experience with Squid shows subjectively reduced artifacts on post-embolization CT scans compared Onyx. To further investigate these observations, we aimed to perform a comparison of between and Onyx in controlled vitro model.Onyx 18 all four variants (Squid 18, low density (LD), 12, 12 LD) were each injected dimethylsulfoxide (DMSO) compatible test tubes. The tubes containing precipitated embolic material inserted phantom for conventional flat panel acquisitions. Beam...
Background There is no consensus regarding optimal antiplatelet regimen for emergent carotid stenting during stroke thrombectomy. We aimed to assess the safety and efficacy of an aggressive periprocedural strategy focused on preserving stent patency, in comparison with conservative consisting aspirin monotherapy. Materials Methods Retrospective review a prospectively collected database comprehensive center, including all cases tandem lesions between 01.03.2012–01.06.2021. Aggressive...
Background and Purpose Data on safety efficacy of intra-arterial (IA) fibrinolytics as adjunct to mechanical thrombectomy (MT) are sparse.Methods INtra-arterial FIbriNolytics In ThrombectomY (INFINITY) is a retrospective multi-center observational registry consecutive patients with anterior circulation large-vessel occlusion ischemic stroke treated MT adjunctive administration IA (alteplase [tissue plasminogen activator, tPA] or urokinase [UK]) at 10 European centers. Primary outcome was the...
We performed a retrospective review in both comprehensive stroke units of region affected early by the coronavirus disease 2019 (COVID-19) pandemic, between March 1 and April 26, 2020, including patients with COVID-19 who underwent mechanical thrombectomy for ischemic stroke. identified 13 cases, representing 38.2% 34 thrombectomies during this period. observed increased mortality high incidence thrombotic complications hospitalization. Given rate infected patients, systematic use full...
To date, the choice of optimal anesthetic management during endovascular therapy (EVT) acute ischemic stroke patients remains subject to debate. We aimed compare functional outcomes and complication rates EVT according first-line in two comprehensive centers: local anesthesia (LA) versus general (GA).Retrospective analysis prospectively collected databases, identifying all consecutive for strokes anterior circulation performed between January 1, 2018 December 31, EVT-capable centers. One...
Cerebral embolism originating from intracardiac tumors represents a rare cause of stroke and has been documented in both adult pediatric populations. We present patient recently diagnosed with right pulmonary hilum tumor, invading the veins left atrium. Two consecutive episodes large cerebral vessel occlusion separate vascular territories occurred same day were treated by mechanical thrombectomy. Embolic material retrieved on occasions contained tumor fragments peripheral endothelialization....
Background Eclipse 2L is a new double lumen balloon microcatheter for neurovascular use, with several design features that separate it from previous generation devices. We aimed to report our initial experience of balloon-assisted coiling intracranial aneurysms using the balloon. Materials and methods Retrospective single-center review patients who underwent balloon, ruptured or unruptured between 1 June 2016 31 December 2018. Cases adjunctive use stents recurrences previously embolized were...
Cerebral embolism originating from intracardiac tumors represents a rare cause of stroke and has been documented in both adult pediatric populations. We present patient recently diagnosed with right pulmonary hilum tumor, invading the veins left atrium. Two consecutive episodes large cerebral vessel occlusion separate vascular territories occurred same day were treated by mechanical thrombectomy. Embolic material retrieved on occasions contained tumor fragments peripheral endothelialization....
Postprocedural dual-antiplatelet therapy is frequently withheld after emergent carotid stent placement during stroke thrombectomy. We aimed to assess whether antiplatelet regimen variations increase the risk of thrombosis beyond postprocedural day 1.Retrospective review was undertaken all consecutive thrombectomies for acute with tandem lesions in anterior circulation performed a single comprehensive center between January 9, 2011 and March 30, 2020. Patients were included if patency...
Objective: To identify factors associated with early angiographic reperfusion improvement (EARI) following intra-arterial fibrinolytics (IAF) after failed or incomplete mechanical thrombectomy (MT). Methods: A subset of patients treated MT and IAF rescue included in the INFINITY (INtra-arterial FIbriNolytics In ThrombectomY) multicenter observational registry was analyzed. Multivariable logistic regression used to EARI. Heterogeneity clinical effect EARI on functional independence (defined...