Mariangela Piano
A5088172457- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Moyamoya disease diagnosis and treatment
- Stroke Rehabilitation and Recovery
- Neurosurgical Procedures and Complications
- Long-Term Effects of COVID-19
- Cerebral Venous Sinus Thrombosis
- Retinal and Optic Conditions
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Meningioma and schwannoma management
- Cardiovascular and Diving-Related Complications
- Spinal Fractures and Fixation Techniques
- Antiplatelet Therapy and Cardiovascular Diseases
- COVID-19 Clinical Research Studies
- Neurological disorders and treatments
- Spine and Intervertebral Disc Pathology
- Vascular Procedures and Complications
- Central Venous Catheters and Hemodialysis
- Blood Coagulation and Thrombosis Mechanisms
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2016-2025
Geisinger Medical Center
2025
Azienda Socio Sanitaria Territoriale Lariana
2021-2024
University Hospital of Basel
2023
University of Basel
2023
University of Bern
2023
Ospedale Maggiore
2021-2023
Ospedale Pediatrico Giovanni XXIII
2023
University Hospital of Bern
2023
Neuroscience Institute
2022
The introduction of flow diverter devices is revolutionizing the endovascular approach to cerebral aneurysms. Midterm and long-term results angiographic, cross-sectional imaging clinical follow-up are still lacking. authors report their experience with treatment intracranial aneurysms using both Pipeline embolization device Silk stents.From October 2008 July 2011 a consecutive series 104 in 101 patients (79 female, 22 male; average age 53 years) were treated. Three ruptured unruptured....
Background Blood blister aneurysms (BBA) are a rare subset of intracranial that represent therapeutic challenge from both surgical and endovascular perspective. Objective To report multicenter experience with flow diversion exclusively for BBA, located at non-branching segments along the anteromedial wall supraclinoidal internal carotid artery (ICA). Methods Consecutive cases BBA ICA treated were included in final analysis. Results 49 patients 51 devices to achieve effect identified. 43 45...
The Pipeline Embolization Device (PED) is a routine first-line treatment option for intracranial aneurysms (IAs). Flex with Shield Technology (Pipeline Shield) an updated version of the PED which has been modified to include surface phosphorylcholine biocompatible polymer. Its early technical success and safety have reported previously. Here, we assessed long-term efficacy IAs.The (PFLEX) study was prospective, single-arm, multicenter unruptured IAs using Shield. primary endpoint major...
Thermosensory signals may contribute to the sense of body ownership, but their role remains highly debated. We test this assumption within framework pathological hypothesising that skin temperature and thermoception differ between right-hemisphere stroke patients with without Disturbed Sensation Ownership (DSO) for contralesional plegic upper limb. Patients DSO exhibit lower basal hand temperatures bilaterally impaired perception cold warm stimuli. Lesion mapping reveals associations in...
<h3>BACKGROUND AND PURPOSE:</h3> Aneurysms of the cavernous segment ICA are difficult to treat with standard endovascular techniques, and sacrifice achieves a high rate occlusion but carries an elevated level surgical complications risk de novo aneurysm formation. We report rates treatment-related data in 44 patients sinus aneurysms treated flow diversion. <h3>MATERIALS METHODS:</h3> Patients diversion were selected from prospectively maintained base 2009 present. Demographic information,...
OBJECTIVE In this single-center series, the authors retrospectively evaluated effectiveness, safety, and midterm follow-up results of ruptured aneurysms treated by implantation a flow diverter device (FDD). METHODS The records 17 patients (12 females, 5 males, average World Federation Neurosurgical Societies score = 2.9) who presented with subarachnoid hemorrhage (SAH) due to rupture an intracranial aneurysm FDD were reviewed. Of aneurysms, 8 blood blister-like remaining 9 dissecting...
Background and purpose The Pipeline Embolization Device (PED) has become a routine first-line option for treatment of intracranial aneurysms (IAs). We assessed the early safety technical success new version PED, Flex with Shield Technology (Pipeline Shield), which same design configuration but been modified to include surface synthetic biocompatible polymer. Materials methods (PFLEX) study is prospective, single-arm, multicenter unruptured IAs using Shield. primary endpoints included...
OBJECT Flow-diversion treatment has been shown to be associated with high rates of angiographic obliteration; however, the is relatively contraindicated in acute phase following subarachnoid hemorrhage (SAH) as these patients require periprocedural dual antiplatelet therapy. Acute coiling followed by flow diversion emerged an intriguing and feasible option for ruptured complex giant aneurysms. In this study authors report outcomes complications aneurysms undergoing planned delayed diversion....
The mechanisms and outcomes in coronavirus disease (COVID-19)-associated stroke are unique from those of non-COVID-19 stroke.To describe the efficacy acute revascularization large vessel occlusion (LVO) setting COVID-19 an international cohort.We conducted multicenter retrospective study consecutively admitted patients with concomitant LVO across 50 comprehensive centers. Our control group constituted historical controls presenting receiving a mechanical thrombectomy between January 2018...
Background The Woven EndoBridge (WEB) device is frequently used for the treatment of intracranial aneurysms. Postoperative management, including use aspirin, varies among clinicians and institutions, but its impact on outcomes WEB has not been thoroughly investigated. Methods This was a retrospective, multicenter study involving 30 academic institutions in North America, South Europe. Data from 1492 patients treated with were included. Patients categorized into two groups based their...
Background and purpose Aspiration thrombectomy of large vessel occlusions has made a comeback among recanalization techniques thanks to recent advances in catheter technology resulting faster promising clinical results when used either alone or as an adjunct stent retriever. This multicenter retrospective study reports angiographic data, complications, outcome patients treated with aspiration the first-line option. Materials methods We analysed procedural data from January 2014 March 2015....
<h3>BACKGROUND AND PURPOSE:</h3> Successful vessel recanalization in posterior circulation large-vessel occlusion is considered crucial, though the evidence of clinical usefulness, compared with anterior circulation, not still determined. The aim this study was to evaluate predictors favorable outcome and analyze effect first-pass thrombectomy. <h3>MATERIALS METHODS:</h3> A retrospective, multicenter, observational conducted 10 high-volume stroke centers Europe, including period from January...
Abstract Purpose Acute ischemic stroke (AIS) due to tandem lesions (TLs) of extracranial Internal Carotid Artery and Anterior Cerebral Circulation are challenging for endovascular treatment (EVT). This study aims evaluate feasibility, safety efficacy EVT TLs’ AIS, with or without emergent carotid artery stenting (eCAS), in a real-life scenario. Methods Retrospective review prospectively collected non-randomized thrombectomy databases from five centers between 2015 2019. Consecutive patients...
While there are reports of acute ischemic stroke (AIS) in coronavirus disease 2019 (COVID-19) patients, the overall incidence AIS and clinical characteristics large vessel occlusion (LVO) remain unclear.To attempt to establish COVID-19 patients an international cohort.A cross-sectional retrospective, multicenter study consecutive admitted with was undertaken from March 1 May 1, 2020 at 12 centers 4 countries. Out those centers, 9 all types strokes data were used calculate rate AIS. Three...
The purpose of this study was to evaluate the effectiveness mechanical thrombectomy (MT) in patients with isolated M2 occlusion and minor symptoms identify possible baseline predictors clinical outcome.The databases 16 high-volume stroke centers were retrospectively screened for consecutive a National Institutes Health Stroke Scale (NIHSS) score ≤5 who received either early MT (eMT) or best medical management (BMM) possibility rescue (rMT) on neurological worsening. Because our not...
BACKGROUND Endovascular thrombectomy allows for detailed study of thrombus composition in acute ischemic stroke. Differences can affect outcomes, and the impact sex on coagulation physiology is recognized. This investigates whether stroke varies between sexes. METHODS Retrospective consecutive endovascular thrombectomy‐treated patients with at Niguarda Hospital 2023. Thrombi were stained hematoxylin eosin, percentages fibrin, red blood cells (RBCs), white (WBCs) quantified as proportions...
Background: Intracranial stenting is still feasible, but its effectiveness investigational. Our study investigated outcomes of endovascular treatment in high-volume and low-volume centres. Methods: We retrospectively recruited 36 patients with intracranial atherosclerosis who underwent from January 2014 to June 2016 at three centres (n = 18), a single centre 18). Detailed periprocedural records, as well clinical radiological follow-up data, were revised through least one-year post-procedure....
Intrasaccular devices have broadened treatment options for wide necked aneurysms. This study presents the preliminary experience with Artisse 2.0 device. Innovative NeurovaScular Product SurveIllance REgistry (INSPIRE) is a non-randomized, multicenter, real world clinical arms aneurysms (INSPIRE-A) and acute ischemic stroke (INSPIRE-S). interim analysis included 87 patients enrolled from November 2022 to April 2024 in INSPIRE-A cohort across 16 Europoean centers. Procedures followed standard...
Background: Intracranial stenting is increasingly performed after thrombectomy failure. Stent selection and procedural strategies are heterogenous between centers. Our aim to evaluate the clinical radiological impact of stent design among these patients. Methods: The RESISTANT registry a multicenter, international, retrospective study patients with acute ischemic stroke who underwent intracranial from 2016 2023. This analysis compares outcomes based on type evaluates role pre- post-stenting...
OBJECTIVE Tobacco smoking is among the factors known to significantly augment risk of untreated intracranial aneurysm (IA) growth and rupture. Smoking appears have a variable effect on different endovascular treatment modalities. The impact safety, efficacy, outcomes Woven EndoBridge (WEB) device use for wide-neck IAs has not been evaluated. This study aimed investigate WEB devices by status. METHODS A retrospective multicenter analysis was conducted data patients from 36 sites worldwide...
Introduction: Infective endocarditis (IE) is a life-threatening condition and rare cause of ischemic stroke (IS). This study aimed to evaluate the utility analyzing cerebral thrombi, obtained through endovascular thrombectomy in IS, for pathological diagnosis IE. Patients methods: Cerebral thrombi from three groups IS patients were compared: definite IE ( n = 10), cardioembolic without with concomitant infection (CE-I − : 30, CE-I + 10). We performed histological examination, molecular...