A5074904854- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Neurosurgical Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Long-Term Effects of COVID-19
- Cerebral Venous Sinus Thrombosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Moyamoya disease diagnosis and treatment
- Cardiovascular and Diving-Related Complications
- Neurological Disease Mechanisms and Treatments
- Neurological Complications and Syndromes
- Radiomics and Machine Learning in Medical Imaging
- Retinal and Optic Conditions
- Oropharyngeal Anatomy and Pathologies
- Neonatal and fetal brain pathology
- Systemic Lupus Erythematosus Research
- Medical Imaging and Analysis
- Vasculitis and related conditions
- Trigeminal Neuralgia and Treatments
- Toxin Mechanisms and Immunotoxins
- Renal Diseases and Glomerulopathies
- Antiplatelet Therapy and Cardiovascular Diseases
Johnson University
2022-2024
Rutgers, The State University of New Jersey
2021-2024
Robert Wood Johnson University Hospital
2020-2024
Albany Medical Center Hospital
2018-2020
Neurological Surgery
2020
University of Rochester Medical Center
2019
Yale Cancer Center
2017
Yale New Haven Hospital
2016-2017
Froedtert Hospital
2013
Medical College of Wisconsin
2013
Background and purpose BRANCH (wide-neck bifurcation aneurysms of the middle cerebral artery basilar apex treated by endovascular techniques) is a multicentre, retrospective study comparing core lab evaluation angiographic outcomes with self-reported outcomes. Materials methods Consecutive patients were enrolled from 10 US centres, aged between 18 85 unruptured wide-neck (MCA) or endovascularly. Patient demographics, aneurysm morphology, procedural information, mortality morbidity data...
While there are reports of acute ischemic stroke (AIS) in coronavirus disease 2019 (COVID-19) patients, the overall incidence AIS and clinical characteristics large vessel occlusion (LVO) remain unclear.To attempt to establish COVID-19 patients an international cohort.A cross-sectional retrospective, multicenter study consecutive admitted with was undertaken from March 1 May 1, 2020 at 12 centers 4 countries. Out those centers, 9 all types strokes data were used calculate rate AIS. Three...
Background Optimal antiplatelet inhibition is vital during cerebrovascular stenting procedures, yet no standardized recommendation exists for antithrombotic therapy in these scenarios. Cangrelor an intravenous P2Y12 inhibitor with a favorable pharmacokinetic profile use neuroendovascular stenting. Methods A retrospective review of all patients who underwent between 1 January 2019 and 22 March 2020 were treated cangrelor was conducted. Thirty-seven met inclusion criteria. Results All...
There is a paucity of literature regarding treatment options for extracranial pseudoaneurysms the internal carotid artery (ICA). To date, Pipeline Embolization Device (PED; Medtronic Inc) use ICA has only been reported from single-center case series.To evaluate safety and efficacy PED pseudoaneurysms.This multicenter retrospective study involving 6 high-volume tertiary academic institutions in United States. We analyzed patients with treated between January 1, 2011, 2019. Clinical assessment...
Background: Long-term safety and efficacy outcomes of Surpass Evolve flow diverter (SEFD) in treatment intracranial aneurysms are lacking. Factors predicting complete aneurysm occlusion elusive literature. Methods: A retrospective review all consecutive treated with SEFD from February 2020 to July 2022, at a single comprehensive stroke center. Results: Fifty-one patients 80 were included. Mean target size was 5.6 mm mean neck-width 3.42 mm. Small (<10 mm) 75% (n=60), while 25% >10...
Chronic subdural hematomas are a common neurosurgical presentation. They difficult to treat, and current interventions – namely surgical evacuation not without complications or recurrences. Embolization of the middle meningeal artery is promising new treatment option for this pathology. We have noted an interesting phenomenon in our patients following endovascular embolization, which that hematoma stained with contrast procedure. This ties into basic physiology chronic subdurals, parasitize...
Ribosome-inactivating proteins, such as the pokeweed antiviral protein (PAP), inhibit translation by depurinating conserved sarcin/ricin loop of large ribosomal RNA. Depurinated ribosomes are unable to bind elongation factor 2, and, thus, translocation step cycle is inhibited. Though consequences depurination well characterized, ribosome conformation required for take place has not been described. In this report, we correlate biochemical and genetic data conclude that depurinates when A-site...
Importance: Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome 2 (SARS-CoV-2), is a global pandemic that has been an immense burden on the healthcare systems all over world. While there are case reports of acute ischemic stroke (AIS) overall incidence in COVID -19 patients yet to be determined. Also, whether hypercoagulability seen COVID-19 leads larger thromboemboli and hence increase large vessel occlusion (LVOs) unclear. Design, Setting, Participants: This...
The neutrophil-lymphocyte ratio (NLR) is emerging as an important biomarker of acute physiologic stress in a myriad medical conditions, and confirmed poor prognostic indicator COVID-19.We sought to describe the role NLR predicting outcome COVID-19 patients undergoing mechanical thrombectomy for ischemic stroke.We analyzed with large vessel occlusion (LVO) strokes enrolled into international 12-center retrospective study laboratory-confirmed COVID-19, consecutively admitted between March 1,...
Background Eagle syndrome (ES) was first described in 1937, to characterize elongation of the styloid process. It is rarely encountered by neurosurgeons but does present potential for vascular sequelae and neurological complications.
Introduction Tandem lesions involving a large vessel occlusion intracranially with concomitant cervical carotid critical stenosis or are common presentation of acute ischemic stroke. These both challenging and time-consuming but can be extremely beneficial for patients when successful. We present technique utilizing the pusher wire stent retriever used intracranial thrombectomy as workhorse intervention using monorail system to perform angioplasty. Methods reviewed four successive who...
We report a case of intracranial abscesses development in patient with head and neck cancer after emergent treatment carotid blowout syndrome coil embolization. Our is 60-year-old male who presented hemoptysis hematemesis, which raised concerns for impending syndrome. Endovascular occlusion was successfully achieved, the discharged stable condition. Ten days later, reported headaches right facial pain, magnetic resonance imaging revealed multiple abscesses. Broad-spectrum intravenous...
Khandelwal, Priyank MD; Al-Mufti, Fawaz Tiwari, Ambooj Singla, Amit Dmytriw, Adam A MD, MPH, MSc; Piano, Mariangela Quilici, Luca Pero, Guglielmo Renieri, Leonardo Limbucci, Nicola Martínez-Galdámez, Mario Schüller-Arteaga, Miguel Galván, Jorge Arenillas-Lara, Juan Francisco Hashim, Zafar Nayak, Sanjeev Desousa, Keith Sun, Hai PhD; Agarwalla, Pankaj K Nanda, Anil Roychowdhury, J Sudipta Nourollahzadeh, Emad Prakash, Tannavi Gandhi, Chirag D Xavier, Andrew R Lozano, Diego Gupta, Gaurav...
Introduction Evidence for improved first-pass effect with the novel radially adjustable radio-opaque stent retriever Tigertriever is lacking. Objective To compare improvement in first pass success using two different techniques—rapid inflation deflation (RID) and suction thrombectomy (ST). Methods Retrospective analysis of patients acute ischemic stroke who underwent mechanical at a single comprehensive center. Results Thirty were included. Mean age was 72.8 years. Twelve (48%) experienced...
Treating dural arteriovenous fistulas (DAVFs) with endovascular embolization has proven to be effective. However, in cases where the DAVF is isolated or inaccessible via conventional methods, a combined surgical and approach may necessary. This strategy provides direct venous system bypasses site of sinus occlusion. In this report, we present case Onyx after navigated cannulation transverse (TS) for treatment left TS DAVF, along review literature on transcranial DAVF. The was embolized Onyx,...
Intracranial atherosclerotic disease (ICAD) is a common cause of stroke with poor natural history despite medical therapy. Few studies have investigated endovascular therapies for the treatment symptomatic ICAD in distal intracranial arteries. Here, we present feasibility and safety balloon angioplasty without stenting patients medically refractory small artery ICAD.Personal logs were reviewed to identify who treated (stenosis > 50%) using ± stenting. Small cerebral arteries defined by...