Amit Singla

ORCID: 0000-0002-8485-9028
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About
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Research Areas
  • Veterinary Practice and Education Studies
  • Acute Ischemic Stroke Management
  • Sarcoma Diagnosis and Treatment
  • Zoonotic diseases and public health
  • Animal Disease Management and Epidemiology
  • Bone fractures and treatments
  • Radiation Dose and Imaging
  • Orthopedic Surgery and Rehabilitation
  • Cerebrovascular and Carotid Artery Diseases
  • Radioactivity and Radon Measurements
  • Stroke Rehabilitation and Recovery
  • Vector-Borne Animal Diseases
  • Soft tissue tumor case studies
  • Cancer-related Molecular Pathways
  • Shoulder Injury and Treatment
  • Spine and Intervertebral Disc Pathology
  • Shoulder and Clavicle Injuries
  • Meningioma and schwannoma management
  • Ubiquitin and proteasome pathways
  • Spinal Fractures and Fixation Techniques
  • Veterinary Pharmacology and Anesthesia
  • Aluminum Alloys Composites Properties
  • Abdominal Trauma and Injuries
  • Orthopedic Infections and Treatments
  • Effects of Environmental Stressors on Livestock

Albert Einstein College of Medicine
2020-2024

Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya
2018-2024

Montefiore Medical Center
2019-2024

Rutgers Sexual and Reproductive Health and Rights
2024

All India Institute of Medical Sciences Bhubaneswar
2023

St. Barnabas Hospital
2022-2023

Maharaja Ranjit Singh Punjab Technical University
2021-2022

Yale University
2021

Yale New Haven Hospital
2021

Swedish Medical Center
2018-2019

Sensors and the internet are used in Internet of Things (IoT) to link physical computer networks. Future IoT development will be heavily influenced by machine learning cloud computing. Wi-Fi ethernet most common methods connecting devices today. Because great range low latency 5G cellular network, gadgets choose it future. This study discusses how overcome limitations early key management systems provides a mechanism that is more effective context. Prior this, network had been deployed was...

10.1109/icesc54411.2022.9885644 article EN 2022 3rd International Conference on Electronics and Sustainable Communication Systems (ICESC) 2022-08-17

Abstract Osteosarcoma(OS) is a highly aggressive bone cancer for which treatment has remained essentially unchanged decades. Although OS characterized by extensive genomic heterogeneity and instability, RB1 TP53 have been shown to be the most commonly inactivated tumor suppressors in OS. We previously generated mouse model with double knockout (DKO) of Rb1 Trp53 within cells osteoblastic lineage, largely recapitulates human nearly complete penetrance. SKP2 repression target pRb serves as...

10.1038/s41388-024-02942-4 article EN cc-by Oncogene 2024-02-14

Endovascular clot retrieval is a technique available for removing intracranial arterial occlusions in acute ischemic stroke (AIS). This rescue therapy can be performed with moderate conscious sedation (CS) or general anesthesia (GA). The effect of GA on clinical outcome AIS remains controversial. Therefore, we retrospectively investigated whether the use CS during endovascular intervention influenced outcomes.Patients who underwent emergent occlusion years 2006 to 2012 were included this...

10.1097/ana.0000000000000031 article EN Journal of Neurosurgical Anesthesiology 2013-11-28

There is an absence of widely accepted guidelines for the management infectious intracranial aneurysms (IIAs) owing to a dearth high-quality evidence in literature.To better define incidence IIAs, treatment practices, and patient outcomes by performing Nationwide Inpatient Sample (NIS) database query.We queried NIS from 2002 2011 all patients with primary diagnosis endocarditis (IE), subarachnoid hemorrhage (SAH), or unruptured cerebral aneurysm ICD-9-CM codes. ICD-9 procedure codes were...

10.1136/neurintsurg-2015-011834 article EN Journal of NeuroInterventional Surgery 2015-06-04

10.1007/s10967-021-07599-x article EN Journal of Radioanalytical and Nuclear Chemistry 2021-01-25

Osteosarcoma is a highly aggressive malignancy for which treatment has remained essentially unchanged years. Our previous studies found that the F-box protein SKP2 overexpressed in osteosarcoma, acting as proto-oncogene; p27Kip1 (p27) an inhibitor of cyclin-dependent kinases and downstream substrate SKP2-mediated ubiquitination. Overexpression underexpression p27 are common characteristics cancer cells. The SCFSKP2 E3 ligase ubiquitinates Thr187-phosphorylated proteasome degradation, can be...

10.1111/nyas.14578 article EN Annals of the New York Academy of Sciences 2021-02-16

Synovial sarcoma (SS) is an aggressive soft-tissue cancer with a poor prognosis and propensity for local recurrence distant metastasis. In this study, we investigated whether S phase kinase-associated protein (Skp2) plays oncogenic role in tumor initiation, progression, metastasis of SS. Our study revealed that Skp2 frequently overexpressed SS specimens SS18-SSX transgenic mouse tumors, as well correlated clinical stages. Next, identified genetic depletion reduced mesenchymal stemness...

10.1016/j.tranon.2020.100809 article EN cc-by-nc-nd Translational Oncology 2020-07-02

Numerous authors over the years have reported that lumbar ligamentum flavum has two layers. Our routine cadaveric dissections raised question whether this understanding is correct, as we always observed only one layer. Thus, goal of study was to reevaluate layers flavum. Twenty levels from five fresh‐frozen specimens were used in study. After dissection spine, and interspinous ligament exposed. Each level transected through zygapophyseal joint, hematoxylin eosin staining, Masson's trichrome...

10.1002/ca.23437 article EN Clinical Anatomy 2019-07-20

OBJECT.: There is limited information regarding patient outcomes following interventions for stroke during the window endovascular therapy. Studies have suggested that recently approved stent retrievers are safer and more effective than earlier-generation thrombectomy devices. The authors compared cases in which Solitaire-FR device was used to those a MERCI or Penumbra used.This study single-center retrospective review of 102 consecutive acute patients were treated with mechanical devices...

10.3171/2014.2.jns131372 article EN Journal of neurosurgery 2014-03-07

Objective: The present study was made to investigate the enhancement in heat transfer characteristics of CuO water base nanofluids by inserting baffles annulus double pipe exchanger. Statistical Analysis: experimentation carried out with distilled and copper oxide at 0.1% 0.2% volume concentration. effect on coefficient Nusselt number is determined this experiment various temperatures. Findings: It has been observed that comparison water, shows more enhancement. result showed increased 8%...

10.17485/ijst/2016/v9i40/101486 article EN Indian Journal of Science and Technology 2016-10-27

Many physicians debate the efficacy of mechanical thrombectomy for ischaemic stroke, but most agree that to establish potential benefit, patient selection must be examined further. People >80 years are a growing population patients with stroke largely excluded from clinical trials. The benefit them may greatly reduced due diminishing neuroplasticity and larger number medical comorbidities. To address this knowledge gap, we economic outcomes after in Nationwide Inpatient Sample. Our null...

10.1136/bmjopen-2013-004480 article EN cc-by-nc BMJ Open 2014-03-01
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