- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Cerebral Venous Sinus Thrombosis
- Long-Term Effects of COVID-19
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Cardiac electrophysiology and arrhythmias
- Oropharyngeal Anatomy and Pathologies
- Vascular Malformations Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Myasthenia Gravis and Thymoma
- Neurological Complications and Syndromes
- Peripheral Neuropathies and Disorders
- Cardiac Arrest and Resuscitation
- Cardiac tumors and thrombi
- Pancreatitis Pathology and Treatment
- Climate Change and Health Impacts
- Retinal and Optic Conditions
- Nutrition and Health in Aging
The University of Texas Health Science Center at Houston
2021-2024
Boston Medical Center
2022
Boston University
2022
Mass General Brigham
2022
Brigham and Women's Hospital
2019-2022
Harvard University
2019-2022
Massachusetts General Hospital
2019-2022
Neurology, Inc
2022
Cornell University
2016-2018
Weill Cornell Medicine
2018
To analyse the clinical characteristics of COVID-19 with acute ischaemic stroke (AIS) and identify factors predicting functional outcome.Multicentre retrospective cohort study patients AIS who presented to 30 centres in USA Canada between 14 March August 2020. The primary endpoint was poor outcome, defined as a modified Rankin Scale (mRS) 5 or 6 at discharge. Secondary endpoints include favourable outcome (mRS ≤2) mortality discharge, ordinal mRS (shift analysis), symptomatic intracranial...
The mechanisms and outcomes in coronavirus disease (COVID-19)-associated stroke are unique from those of non-COVID-19 stroke.To describe the efficacy acute revascularization large vessel occlusion (LVO) setting COVID-19 an international cohort.We conducted multicenter retrospective study consecutively admitted patients with concomitant LVO across 50 comprehensive centers. Our control group constituted historical controls presenting receiving a mechanical thrombectomy between January 2018...
In medically refractory idiopathic intracranial hypertension (IIH), venous sinus stenosis (VSS) stenting has been an effective treatment modality. Among patients who experience recurrent symptoms and develop new stenosis, the optimal strategy is unknown. The aim of this study was to investigate role rescue re-stenting in with recurrence after prior successful stenting. This a single center, retrospective review from prospectively maintained IIH registry. Between 2012 2023, underwent...
Background Because of the variability in patient responses to clopidogrel and reduce risk thromboembolic complications, adjusting antiplatelet regimen based on platelet function testing has become a widespread practice neurointervention. We aimed explore current patterns related this practice. Methods conducted survey targeting neurointerventionalists, comprising multiple‐choice questions opportunities for free‐text when necessary. The was distributed via professional society distribution...
Chronic subdural hematoma (CSDH) is an increasingly prevalent disease in the aging population. Patients with CSDH frequently suffer from concurrent vascular or develop secondary thrombotic complications requiring antithrombotic treatment.To determine safety and impact of early reinitiation antithrombotics after middle meningeal artery embolization for chronic hematoma.This a single-institution, retrospective study patients who underwent (MMA) embolizations CSDH. Patient without initiation...
The development and validation study of the Clinical Chronic Obstructive Disease (COPD) Questionnaire (CCQ) has recently been published in this journal. CCQ is first questionnaire that incorporates both clinician patient guideline goals clinical control evaluation patients with COPD general practice. aim Italian, specific pulmonary disease practice.Validity was tested on a population healthy subjects COPD, using Italian validated version Short Form Health Survey (SF-36) recommended routine...
Previous studies suggest that mechanisms and outcomes in patients with COVID-19-associated stroke differ from those non-COVID-19-associated strokes, but there is limited comparative evidence focusing on these populations. The aim of this study, therefore, was to determine if a significant association exists between COVID-19 status revascularization functional following thrombectomy for large vessel occlusion (LVO), after adjustment potential confounding factors.A cross-sectional,...
Background Acute ischemic stroke (AIS) in the context of COVID‐19 has received considerable attention for its propensity to affect patients all ages. We aimed evaluate effect age on functional outcome and mortality following an acute event. Methods Results A prospectively maintained database from comprehensive centers Canada United States was analyzed with AIS March 14 September 30, 2020 who tested positive SARS‐CoV‐2. The primary Modified Rankin Scale score at discharge, secondary...
Middle meningeal artery embolization (MMAE) has emerged as a promising new treatment for patients with chronic subdural hematomas (cSDH). Its efficacy, however, upon the subtype high rate of recurrence-septated cSDH-remains undetermined.From our prospective registry cSDH treated MMAE, we classified based on presence or absence septations. The primary outcome was recurrence cSDH. Secondary outcomes included reduction in thickness, midline shift, and reoperation.Among 80 99 cSDHs, median age...
Introduction: Plavix resistance is an independent risk factor for thromboembolic complications following carotid artery stent (CAS) placements. The VerifyNow P2Y12 assay the best studied in gauging responsiveness. Its performance affected when hematocrit (HCT) value <33%, and prevalence of anemia acute stroke patients 30%. Hence, we effect low HCT on response units (PRU) with symptomatic stenosis who received CAS. Methods: We included suffered ischemic strokes CAS during same...
Introduction Venous sinus stenosis (VSS) stenting in medically refractory Idiopathic Intracranial Hypertension (IIH) patients has emerged as an effective treatment with low rates of failure and recurrence. However, the best strategy following recurrence symptoms previously stented initial response is unclear frequently leads to shunt placement. We investigated role re‐stenting after prior successful stenting. Methods This a retrospective review prospectively maintained IIH registry....
Introduction Chronic Subdural Hematoma (cSDH) is projected to be the most common neurosurgical disease in US by end of decade. MMA embolization a promising new treatment; however, its efficacy patients with complex, septated cSDH remains uncertain. Methods From our prospectively maintained registry treated (with or without concurrent surgical drainage), we identified and septations. Septations were defined as hyperdense septa between inner outer membranes on lower‐density background. The...
Introduction Due to the variability in patient responses clopidogrel, adjusting antiplatelet regimen based on platelet function testing has become a widespread practice reduce thromboembolic complications neurointervention. In absence of standardized guideline, we aimed explore patterns related clopidogrel resistance. Methods We conducted survey targeting neurointerventionalists, comprising multiple‐choice questions and opportunities for free‐text when necessary. The was distributed via...