Fabio Settecase
A5053975875- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Stroke Rehabilitation and Recovery
- Peripheral Artery Disease Management
- Long-Term Effects of COVID-19
- Traumatic Brain Injury and Neurovascular Disturbances
- MRI in cancer diagnosis
- Cerebral Venous Sinus Thrombosis
- COVID-19 Clinical Research Studies
- Meningioma and schwannoma management
- Vascular Anomalies and Treatments
- Advanced X-ray and CT Imaging
- Medical Imaging and Analysis
- Cardiac Imaging and Diagnostics
- Radiation Dose and Imaging
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological Disease Mechanisms and Treatments
- Atomic and Subatomic Physics Research
- Trigeminal Neuralgia and Treatments
- Renal and Vascular Pathologies
- Glioma Diagnosis and Treatment
California Pacific Medical Center
2022-2025
University of British Columbia
2018-2025
Mills Peninsula Health Services
2023-2025
Sutter Health
2024-2025
Vancouver General Hospital
2018-2024
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Vancouver Coastal Health Research Institute
2021
University of California, San Francisco
2010-2020
University of California System
2015-2020
Hoag Memorial Hospital Presbyterian
2017-2018
BackgroundWhether the large effect size of endovascular thrombectomy (EVT) for stroke due to large-vessel occlusion applies medium-vessel is unclear.MethodsIn a multicenter, prospective, randomized, open-label trial with blinded outcome evaluation, we assigned patients acute ischemic who presented within 12 hours from time that they were last known be well and had favorable baseline noninvasive brain imaging receive EVT plus usual care or alone. The primary was modified Rankin scale score...
<h3>SUMMARY:</h3> Spontaneous lateral sphenoid cephaloceles arise from bony defects in the sphenoid, absence of predisposing factors such as trauma, surgery, mass, or congenital skull base malformation. We reviewed CT and MR imaging findings clinical data 26 patients with spontaneous to better understand anatomic contributions pathogenesis, varying manifestations, descriptive terminology. Two types were identified. In 15 patients, a type 1 cephalocele was noted, herniating into pneumatized...
To analyse the clinical characteristics of COVID-19 with acute ischaemic stroke (AIS) and identify factors predicting functional outcome.Multicentre retrospective cohort study patients AIS who presented to 30 centres in USA Canada between 14 March August 2020. The primary endpoint was poor outcome, defined as a modified Rankin Scale (mRS) 5 or 6 at discharge. Secondary endpoints include favourable outcome (mRS ≤2) mortality discharge, ordinal mRS (shift analysis), symptomatic intracranial...
The mechanisms and outcomes in coronavirus disease (COVID-19)-associated stroke are unique from those of non-COVID-19 stroke.To describe the efficacy acute revascularization large vessel occlusion (LVO) setting COVID-19 an international cohort.We conducted multicenter retrospective study consecutively admitted patients with concomitant LVO across 50 comprehensive centers. Our control group constituted historical controls presenting receiving a mechanical thrombectomy between January 2018...
Collateral blood supply is a key determinant of outcome in large-vessel occlusion acute ischemic stroke. Single- and multiphase CTA collateral scoring systems have been described but are subjective require training. We aimed to test whether the CTP-derived hypoperfusion intensity ratio associated with status threshold exists that predicts poor collaterals.Imaging clinical data consecutive patients stroke were retrospectively reviewed. Single-phase performed by 2 blinded neuroradiologists...
Current applied to wire coils wound at the tip of an endovascular catheter can be used remotely steer a under magnetic resonance imaging guidance. In this study, we derive and validate equation that characterizes relationship between deflection number physical factors: , where is angle, solenoidal turns, current, cross‐sectional area tip, (MR) scanner main field, unconstrained length, Young's Modulus for material, moment inertia, initial angle . Solenoids 50, 100, or 150 turns were on...
BACKGROUND Venous sinus stenting (VSS) is increasingly performed for managing venous stenosis associated with refractory idiopathic intracranial hypertension and/or pulsatile tinnitus. The Monopoint System (MS; Route 92 Medical, San Mateo, CA) a telescoping catheter system single point of control outside the body, consisting an 8F Guide Catheter (Base Camp), 0.088‐in. inner diameter catheter‐extender (HiPoint 88), and ledge‐reducing delivery (Tenzing 8). In this study, we describe MS...
Background Medium vessel occlusions (MeVOs) account for 25–40% of acute ischemic stroke. The Tenzing 5 (Route 92 Medical, San Mateo, California, USA) and FreeClimb 54 catheter is a novel delivery–aspiration combination designed to facilitate aspiration thrombectomy (AT) MeVOs. We report our clinical experience using the assisted delivery (TADA) technique with first-line AT MeVO. Methods retrospectively reviewed consecutive patients who underwent MeVO TADA at nine institutions in USA one New...
The novel coronavirus disease 2019 (COVID-19) pandemic led to the implementation of wide-ranging institutional infection control protocols. purpose this study is determine effect on outcomes large vessel occlusion (LVO) acute ischemic stroke (AIS) patients treated with endovascular therapy (EVT). Data were obtained from prospectively collected quality improvement databases at six Canadian comprehensive centres March 11, 2020 2021. This patient cohort was compared pre-pandemic consecutively...
<h3>BACKGROUND AND PURPOSE:</h3> Endovascular navigation under MR imaging guidance can be facilitated by a catheter with steerable microcoils on the tip. Not only do create visible artifacts allowing tracking, but also they small magnetic moment permitting remote-controlled tip deflection. A side product of electrical currents, however, is heat that might damage blood vessels. We sought to determine upper boundary currents safely usable at 1.5T in coil-tipped microcatheter system....
Previous comparative mechanical thrombectomy device trials reported a substantial crossover rate from first-line aspiration to stent-retriever thrombectomy. A specialized delivery catheter may help track large-bore catheters target occlusions. We report our multicenter experience of intracranial large vessel occlusions using the FreeClimbTM 70 and Tenzing® 7 (Route 92, San Mateo, CA).After local Institutional Review Board approval, we retrospectively reviewed clinical, procedural, imaging...
<h3>BACKGROUND AND PURPOSE:</h3> Lacunar infarcts account for approximately 25% of acute ischemic strokes. Compared with NCCT alone, the addition CTP improves sensitivity detection overall. Our aim was to systematically evaluate diagnostic benefit and interobserver reliability an incremental CT protocol in lacunar infarction. <h3>MATERIALS METHODS:</h3> Institutional review board approval patient consent were obtained. One hundred sixty-three patients presenting a syndrome ≤4.5 hours from...
<h3>BACKGROUND AND PURPOSE:</h3> Brain parenchymal hyperdensity on postthrombectomy CT in patients with acute stroke can be due to hemorrhage and/or contrast staining. We aimed determine whether iodine concentration within contrast-stained parenchyma compared an internal reference the superior sagittal sinus dual-energy could predict subsequent intracerebral hemorrhage. <h3>MATERIALS METHODS:</h3> Seventy-one small infarct cores (ASPECTS ≥ 7) and good endovascular recanalization (modified...
<h3>BACKGROUND AND PURPOSE:</h3> A minority of intracranial dural arteriovenous fistulas progress with time. We sought to determine features that predict progression and define outcomes patients progressive fistulas. <h3>MATERIALS METHODS:</h3> performed a retrospective imaging clinical record review fistula evaluated at our hospital. <h3>RESULTS:</h3> Of 579 fistulas, 545 had 1 (mean age, 45 ± 23 years) 34 (5.9%) enlarging, de novo, multiple, or recurrent 53 20 years; <i>P</i> = .11). Among...
<h3>SUMMARY:</h3> In the endovascular treatment of cerebral arteriovenous malformations, ethanol sclerotherapy is seldom used due to safety concerns. However, when limited reflux an embolic agent permissible or there a long distance target, may be preferable. We reviewed 10 patients with 14 AVM feeding artery aneurysms intranidal treated intra-arterial at our institution between 2005 and 2014. All presented acute intracranial hemorrhage. Thirteen were primarily 60%–80% into artery. Complete...
Previous studies suggest that mechanisms and outcomes in patients with COVID-19-associated stroke differ from those non-COVID-19-associated strokes, but there is limited comparative evidence focusing on these populations. The aim of this study, therefore, was to determine if a significant association exists between COVID-19 status revascularization functional following thrombectomy for large vessel occlusion (LVO), after adjustment potential confounding factors.A cross-sectional,...
Background Acute ischemic stroke (AIS) in the context of COVID‐19 has received considerable attention for its propensity to affect patients all ages. We aimed evaluate effect age on functional outcome and mortality following an acute event. Methods Results A prospectively maintained database from comprehensive centers Canada United States was analyzed with AIS March 14 September 30, 2020 who tested positive SARS‐CoV‐2. The primary Modified Rankin Scale score at discharge, secondary...
Aspiration catheters are widely used for thrombectomy either alone or in combination with a stent-retriever, distal inner diameter and trackability keys to their success. In an illustrative case series, we report our clinical experience AXS Vecta (Stryker Neurovascular, Fremont, CA, USA), available both 0.071-inch 0.074-inch diameters, including the first 2 74 cases reported. A literature review on is also provided. 9 thrombectomies were performed (Vecta 71: M1, 5 M2 occlusions; 74: 1 M1...