A5043227864- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Peripheral Artery Disease Management
- Stroke Rehabilitation and Recovery
- Moyamoya disease diagnosis and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Diversity and Career in Medicine
- Innovations in Medical Education
- Neurological Complications and Syndromes
- Clinical practice guidelines implementation
- Cardiac, Anesthesia and Surgical Outcomes
- Health and Medical Research Impacts
- Aortic aneurysm repair treatments
- Retinal and Optic Conditions
- Cardiovascular Health and Disease Prevention
- History of Medical Practice
- Cerebrovascular and genetic disorders
- Dental Education, Practice, Research
- Pituitary Gland Disorders and Treatments
Université Laval
2009-2025
Centre Hospitalier de l’Université de Montréal
2024
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Centre hospitalier universitaire de Québec
2019-2021
Centre hospitalier de l'Université Laval
2012-2019
Hôpital de l'Enfant-Jésus
2009-2017
Ste. Genevieve County Memorial Hospital
2013
University of Alabama at Birmingham
2009
Louisiana Hematology Oncology Associates
2009
Oregon Health & Science University
2009
Background and Purpose — We sought to better define the morbidity of endovascular Guglielmi detachable coil (GDC) treatment unruptured cerebral aneurysms discuss its role in prevention subarachnoid hemorrhage. Methods conducted an observational study from August 1992 June 1999 125 treated with GDC 116 patients: 91 women (78.4%) 25 men (21.6%), aged 30 78 years (mean age, 50.6 years). Immediate late clinical results were recorded for any neurological event or hemorrhage related aneurysm....
Background: Variants in the ring finger protein 213 ( RNF213 ) gene are known to be associated with increased predisposition cerebrovascular diseases development. Genomic studies have identified as a major risk factor of Moyamoya disease East Asian descendants. However, little is about (ring 213) biological functions or its pathogenic mechanisms underlying disease. Methods: To investigate loss-of-function effect endothelial cell, stable RNF213-deficient human cerebral cells were generated...
Abstract BACKGROUND Aneurysm recurrence after coiling has been associated with aneurysm growth, (re)hemorrhage, and a greater need for follow-up. The second-generation HydroCoil Embolic System (HES; MicroVention, Inc) consists of platinum core integrated hydrogel was developed to reduce through enhancing packing density healing within the aneurysm. OBJECTIVE To compare between HES bare coil (BPC) in new-generation Hydrogel Endovascular Treatment Trial (HEAT). METHODS HEAT is randomized,...
The novel coronavirus disease 2019 (COVID-19) pandemic led to the implementation of wide-ranging institutional infection control protocols. purpose this study is determine effect on outcomes large vessel occlusion (LVO) acute ischemic stroke (AIS) patients treated with endovascular therapy (EVT). Data were obtained from prospectively collected quality improvement databases at six Canadian comprehensive centres March 11, 2020 2021. This patient cohort was compared pre-pandemic consecutively...
Background and Purpose— Several carotid endarterectomy randomized, controlled trials series have reported higher perioperative stroke death rates for women compared with men. The potential this same relationship artery stenting was examined in the lead-in phase of Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). Methods— CREST compares efficacy preventing stroke, myocardial infarction, periprocedural period ipsilateral over follow-up period. included a “lead-in”...
The purpose of this study was to estimate the performance measures MR angiography (MRA) in diagnosis aneurysm residual flow after coil occlusion.Patients having at least 1 cerebral treated with occlusion were prospectively and consecutively enrolled. Time flight contrast-enhanced MRA performed same day DSA follow-up. degree dimensions evaluated by independent readers digital subtraction angiogram. estimated a cross-sectional analysis repeated subgroups sizes locations. predictive values for...
There are only few data and lack of consensus regarding antiplatelet management for carotid stent placement in the setting endovascular stroke treatment. We aimed to develop a consensus-based algorithm acute ischemic patients undergoing treatment simultaneous emergent placement. performed literature search modified Delphi approach used Web-based questionnaires that were sent several iterations an international multidisciplinary panel 19 neurointerventionalists from 7 countries. The first...
We report a severe adverse event occurring in the course of cohort study (ISRCTN13784335) aimed at measuring efficacy and safety venous stenting treatment patients with medically refractory idiopathic intracranial hypertension (IIH). The patient was 41-year-old woman who not overweight, presented headache, grade 1 bilateral papilledema transient tinnitus, to medical treatment. Right transverse sinus successfully performed. Following surgery, patient’s state consciousness decreased acutely...
Small iatrogenic brain infarcts are often seen on diffusion-weighted MRI (DWI) following surgical or endovascular procedures, but there few data their clinical effects. We examined the association of with outcomes in ENACT (Evaluating Neuroprotection Aneurysm Coiling Therapy) randomized controlled trial nerinetide patients undergoing repair intracranial aneurysms.In this post hoc analysis, we used multivariable models to evaluate presence and number DWI neurologic impairment (NIH Stroke...
OBJECTIVE Although the past decades have seen a steady increase of women in medicine general, continue to represent minority physician-training staff and workforce neurosurgery Canada worldwide. As such, aim this study was analyze experiences faculty practicing across better understand address factors contributing disparity. METHODS A historical, cross-sectional, mixed-method analysis survey responses performed using results obtained from attending neurosurgeons Canada. web-based platform...
Background and Purpose- Intracranial aneurysm (IA) size location are important determinants of rupture risk. In familial IAs there is concordance location; however, if such exists for unknown. We analyzed the at time in IAs. Methods- pairs affected relatives with aneurysmal subarachnoid hemorrhage, ratio between largest smallest was calculated. also compared proportion families which both ruptured a < or ≥7 mm one IA <7 another mm. calculated repeatability corresponding 95% CI rupture....
A 60-year-old right-handed woman was admitted to the hospital and discharged same day following an uneventful endovascular repair (coil embolization) of asymptomatic aneurysm. She returned emergency deparment (ED) on next with fever confusion. described by family as doing well in morning, but vomiting several times after lunch. also showed a brief sustained deviation eyes head left, followed clonic movements left hemibody. On her way ED, she amnesia for recent events repeatedly asked why...
<h3>BACKGROUND AND PURPOSE:</h3> The best management of patients with persistent distal occlusion after mechanical thrombectomy or without IV thrombolysis remains unknown. We sought to evaluate the variability and agreement in decision-making for occlusions. <h3>MATERIALS METHODS:</h3> A portfolio 60 cases was sent clinicians varying backgrounds experience. Responders were asked whether they considered conservative rescue therapy (stent retriever, aspiration, intra-arterial thrombolytics) a...
A 57-year-old daycare educator presented as a drowsy but oriented individual with history of sudden and severe headache associated vomiting. She had no previous medical or neurological history. Examination showed focal signs routine laboratory studies were unremarkable. Head computed tomogram (CT) revealed Fisher grade IV subarachnoid hemorrhage in the posterior fossa extensive intraventricular (Graeb 8/12, see Figures 1A 1B) which was shown to originate from left Posterior Inferior...
Procedure-related rupture is one of the most feared complications in treating patients with cerebral aneurysm. The primary aim this study was to estimate effect aneurysm size on procedure-related rupture. We also estimated its peri-procedural thromboembolic events. This observational conducted using routinely-collected health data admitted for subarachnoid hemorrhage and treated coil occlusion CHU de Québec — Enfant-Jésus hospital from January 1st, 2000 until sample reached. Patients were...
Background: Hormone replacement therapy (HRT) was among factors considered in a post-hoc assessment of the risk revascularization by carotid artery stenting (CAS) or endarterectomy (CEA) women enrolled CREST. Methods: Of 872 CREST, 775 (89%) were post-menopausal and current HRT status known 739 (95%). The study composite outcome defined as any stroke, myocardial infarction, death during periprocedural period, plus ipsilateral stroke over 4-year follow-up period. Treatment groups combined...
BACKGROUND: Hormone replacement therapy (HRT) was among factors considered in a post-hoc assessment of the risk revascularization by carotid artery stenting (CAS) or endarterectomy (CEA) women enrolled CREST. DESIGN/METHODS: Of 872 CREST, 775 (89%) were post-menopausal and current HRT status known 739 (95%). The study composite outcome defined as any stroke, myocardial infarction, death during periprocedural period, plus ipsilateral stroke over 4-year follow-up period. Treatment groups...
Background: Women continue to represent a minority of the neurosurgery workforce in Canada. We herein aim provide an update current Canadian landscape gain better understanding factors contributing this disparity. Methods: Chain-referral sampling, interviews, personal communications, and online resources were used as data sources. Online survey results obtained from women attending neurosurgeons across Canada also utilized. Quantitative analyses performed, including summary comparative...