A5052601112- Digital Mental Health Interventions
- Mental Health Research Topics
- Impact of Technology on Adolescents
- Esophageal and GI Pathology
- Mobile Health and mHealth Applications
- COVID-19 and Mental Health
- Heart Failure Treatment and Management
- Eosinophilic Esophagitis
- Skin Protection and Aging
- Health disparities and outcomes
- Esophageal Cancer Research and Treatment
- Inflammatory Bowel Disease
- Health Literacy and Information Accessibility
- Gastric Cancer Management and Outcomes
- Bipolar Disorder and Treatment
- Gastroesophageal reflux and treatments
- Dermatology and Skin Diseases
- Gastrointestinal Bleeding Diagnosis and Treatment
- Electrolyte and hormonal disorders
- Orthopaedic implants and arthroplasty
- Cardiovascular Function and Risk Factors
- Medication Adherence and Compliance
- Colorectal Cancer Screening and Detection
- Musculoskeletal pain and rehabilitation
- Total Knee Arthroplasty Outcomes
Northwestern University
2016-2025
Institute on Aging
2023
Parkview Health
2022
Pfizer (United Kingdom)
2022
University of Westminster
2022
Sanofi (France)
2022
Lundbeck (Italy)
2022
Weatherford College
2022
Eli Lilly (United States)
2022
Gordon and Betty Moore Foundation
2022
Several studies indicate the importance of colonic microbiota in metabolic and inflammatory disorders diet on composition. The effects alcohol, one prominent components diet, bacterial composition is largely unknown. Mounting evidence suggests that gut-derived endotoxins are cofactors for alcohol-induced tissue injury organ failure like alcoholic liver disease (ALD) only occur a subset alcoholics. We hypothesized chronic alcohol consumption results alterations gut microbiome subgroup...
The evolving outbreak of coronavirus disease 2019 (COVID-19) is requiring social distancing and other measures to protect public health. However, messaging has been inconsistent unclear.
Background: Digital mental health tools have tended to use psychoeducational strategies based on treatment orientations developed and validated outside of digital health. These features do not map well the brief but frequent ways that people mobile phones phone apps today. To address these challenges, we a suite for depression anxiety called IntelliCare, each with focused goal interactional style. IntelliCare prioritize interactive skills training over education are designed short interactions.
In recent years, there has been increasing discussion of the limitations traditional randomized controlled trial (RCT) methodologies for evaluation eHealth and mHealth interventions, in particular, requirement that these interventions be locked down during evaluation. Locking locks defects eliminates opportunities quality improvement adaptation to changing technological environment, often leading validation tools are outdated by time results published. Furthermore, because behavioral...
Abstract Introduction: One of the proposed second hit mechanisms in pathophysiology non‐alcoholic steatohepatitis (NASH) is hepatic oxidative stress triggered by elevated levels endotoxin. We investigated one possible mechanism for endotoxaemia – disruption intestinal barrier integrity. Methods: enrolled 16 subjects with fatty liver (10 NASH; 6 steatosis) and 12 healthy subjects. Steatosis NASH were diagnosed biopsy using Brunt criteria. Gastrointestinal permeability was measured urinary...
Checklists may reduce errors of omission for critically ill patients.To determine whether prompting to use a checklist improves process care and clinical outcomes.We conducted cohort study in the medical intensive unit (MICU) tertiary university hospital. Patients admitted either two independent MICU teams were included. Intervention team physicians prompted address six parameters from daily rounding if overlooked during morning work rounds. The second (control) used identical without...
Background Web-based interventions for depression that are supported by coaching have generally produced larger effect-sizes, relative to standalone web-based interventions. This is likely due the effect of on adherence. We evaluated efficacy a manualized telephone intervention (TeleCoach) aimed at improving adherence (moodManager), as well relationship between and depressive symptom outcomes. Methods 101 patients with MDD, recruited from primary care, were randomized 12 weeks...
We reviewed our multicenter experience with gamma-delta (γδ) T-cell lymphomas first presenting in the skin. Fifty-three subjects a median age of 61 years (range, 25 to 91 y) were diagnosed this disorder. The duration skin lesions at presentation was 1.25 1 mo 20 y). most common deep plaques (38 cases) often resembling panniculitis, followed by patches psoriasis or mycosis fungoides (10 cases). These tended ulcerate overtime (27 Single localized areas involvement cellulitis pyoderma reported...
To investigate the relationship of excess and central adiposity with pediatric psoriasis severity.Multicenter, cross-sectional study 409 psoriatic children. Psoriasis was classified as mild (worst Physician's Global Assessment score ≤3 body surface area ≤10%) or severe ≥3 >10%). Children were enrolled from 9 countries between June 19, 2009, December 2, 2011.Excess (body mass index percentile) (waist circumference percentile waist to height ratio).Excess ≥85th occurred in 37.9% children...
<h3>Importance</h3> Depression and anxiety are common disabling. Primary care is the de facto site for treating these mental health problems but typically underresourced to meet burden of demands. <h3>Objective</h3> To evaluate efficacy a mobile intervention platform, IntelliCare, addressing depression among primary patients. <h3>Design, Setting, Participants</h3> Two-arm randomized clinical trial at internal medicine clinics University Arkansas Medical Sciences. Adult patients (N = 146) who...
Abstract The clinical features of pediatric psoriasis warrant further attention. A national study was conducted to determine the prevalence scalp and nail involvement a history guttate at onset according age, sex, disease severity. One hundred eighty‐one children ages 5 17 years with plaque were enrolled in multicenter, cross‐sectional study. Subjects guardians asked about whether initial presentation guttate. Peak severity assessed defined historically as mild ( MP ) or severe SP P...
Background IntelliCare is a modular platform that includes 12 simple apps targeting specific psychological strategies for common mental health problems. Objective This study aimed to examine the effect of 2 methods maintaining engagement with platform, coaching, and receipt weekly recommendations try different on depression, anxiety, app use. Methods A total 301 participants depression or anxiety were randomized 1 4 treatments lasting 8 weeks followed 6 months posttreatment. The trial used...
Atopic dermatitis (AD) is associated with multiple potential risk factors for obesity and high blood pressure (BP), including chronic inflammation, sleep disturbance, mental health comorbidity. Previous studies found associations between general AD. However, it unknown whether AD central and/or BP.To determine BP are increased in pediatric AD.This case-control study performed multicenter dermatology practices the United States recruited 132 children (age range, 4-17 years) active moderate to...
Background User engagement is key to the effectiveness of digital mental health interventions. Considerable research has examined clinical outcomes overall with apps (eg, frequency and duration app use). However, few studies have how specific use behaviors can drive change in outcomes. Understanding more nuanced could inform design that are clinically effective users. Objective This study aimed classify user a suite examine different types related depression anxiety We also compare those...
The US outbreak of coronavirus disease 2019 (COVID-19) accelerated rapidly over a short time to become public health crisis. To assess how high-risk adults' COVID-19 knowledge, beliefs, behaviors, and sense preparedness changed from the onset (March 13–20, 2020) acceleration phase 27–April 7, 2020). Longitudinal, two-wave telephone survey. 588 predominately older adults with ≥ 1 chronic condition recruited 4 active, federally funded studies in Chicago. Self-reported knowledge symptoms...
There are currently no criteria for ineffective esophageal motility (IEM) and swallow (IES) in pressure topography (EPT). Our aims were to use high-resolution manometry metrics define IEM within the Chicago Classification determine distal contractile integral (DCI) threshold IES.The EPT of 150 patients with either dysphagia or reflux symptoms reviewed. Peristaltic function was defined by Classification; corresponding conventional line tracing (CLT) reviewed separately. Generalized linear...
Risk factors for development of catheter-related bloodstream infections (CRBSI) were studied in 125 adults and 18 children who received home parenteral nutrition (HPN).Medical records from a national care pharmacy reviewed all patients that had HPN infused at least twice weekly minimum two years January 1, 2006-December 31, 2011. Infection risk factor data collected during this time period on although those longer since initiation HPN.In adults, 331 central venous catheters (CVCs) placed....