A5057572299- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiovascular and exercise physiology
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Diabetes Treatment and Management
- Heart Rate Variability and Autonomic Control
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Electrolyte and hormonal disorders
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Hormonal Regulation and Hypertension
- Long-Term Effects of COVID-19
- Cardiac, Anesthesia and Surgical Outcomes
- Receptor Mechanisms and Signaling
- Cardiac Valve Diseases and Treatments
- Blood Pressure and Hypertension Studies
- Cardiovascular Effects of Exercise
- Hemodynamic Monitoring and Therapy
- Cardiac Health and Mental Health
- Potassium and Related Disorders
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Arrhythmias and Treatments
University of Brescia
2016-2025
Imperial College Healthcare NHS Trust
2025
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2007-2024
Brescia University
2001-2024
National Heart Centre Singapore
2024
British Heart Foundation
2024
National Heart Hospital
2024
Surgical Specialties (Canada)
2017-2024
University of Palermo
2016-2023
University of Cagliari
2016-2023
Abstract Aims To evaluate the impact of COVID-19 pandemic on patient admissions to Italian cardiac care units (CCUs). Methods and Results We conducted a multicentre, observational, nationwide survey collect data for acute myocardial infarction (AMI) at CCUs throughout 1 week period during outbreak, compared with equivalent in 2019. observed 48.4% reduction AMI 2019 (P < 0.001). The was significant both ST-segment elevation [STEMI; 26.5%, 95% confidence interval (CI) 21.7–32.3; P =...
Abstract Aims To compare demographic characteristics, clinical presentation, and outcomes of patients with without concomitant cardiac disease, hospitalized for COVID-19 in Brescia, Lombardy, Italy. Methods results The study population includes 99 consecutive pneumonia admitted to our hospital between 4 March 25 2020. Fifty-three a history disease were compared 46 disease. Among patients, 40% had heart failure, 36% atrial fibrillation, 30% coronary artery Mean age was 67 ± 12 years, 80 (81%)...
BackgroundSteroidal mineralocorticoid receptor antagonists reduce morbidity and mortality among patients with heart failure reduced ejection fraction, but their efficacy in those mildly or preserved fraction has not been established. Data regarding the safety of nonsteroidal antagonist finerenone are needed.MethodsIn this international, double-blind trial, we randomly assigned a left ventricular 40% greater, 1:1 ratio, to receive (at maximum dose 20 mg 40 once daily) matching placebo,...
Aims To describe the baseline characteristics of participants in FINEARTS‐HF trial, contextualized with prior trials including patients heart failure (HF) mildly reduced and preserved ejection fraction (HFmrEF/HFpEF). The trial is comparing effects non‐steroidal mineralocorticoid receptor antagonist finerenone placebo reducing cardiovascular death total worsening HF events HFmrEF/HFpEF. Methods results Patients symptomatic HF, left ventricular (LVEF) ≥40%, estimated glomerular filtration...
Abstract Aims The last released European guidelines on the management of heart failure (HF) recommend in patients with chronic HF reduced ejection fraction (HFrEF) a pharmacological approach based four fundamental drugs to be rapidly implemented and then uptitrated modify disease progression. aim Optimization Therapy Italian Management Heart Failure (OPTIMA‐HF) registry is collect data outpatients different settings care. In present analysis, we report first analysis OPTIMA‐HF registry,...
Background —Both metoprolol and carvedilol produce hemodynamic clinical benefits in patients with chronic heart failure; exerts greater antiadrenergic effects than metoprolol, but it is unknown whether this pharmacological difference results differences between the 2 drugs. Methods Results —We randomized 150 failure (left ventricular ejection fraction ≤0.35) to double-blind treatment either or carvedilol. When compared (124±55 mg/d), treated (49±18 mg/d) showed larger increases left at rest...
Background— Low lymphocyte count has been shown to be an independent prognostic marker in heart failure (HF) the outpatient setting. Limited data exist regarding whether relative correlates with postdischarge outcomes patients hospitalized for HF. Methods and Results— We performed a post hoc analysis of Efficacy Vasopressin Antagonism Heart Failure Outcome Study Tolvaptan (EVEREST) trial, which randomized 4133 worsening HF ejection fraction ≤40% within 48 hours admission tolvaptan or placebo...
The prevention of cardiovascular diseases is a fundamental pillar for reducing morbidity and mortality caused by non-communicable diseases. Social determinants, such as socioeconomic status, education, neighborhood, physical environment, employment, social support networks, access to health care, play crucial role in influencing outcomes inequities within populations. determinants stress women are interconnected factors that can significantly impact women’s well-being. Pregnancy good time...
Background: The 6-min walking test (6MWT) is a simple test, which does not require expensive equipment or advanced training. It has been used in heart failure patients to assess exercise tolerance, the effects of therapy and prognosis. Accordingly, post-surgical cardiac rehabilitation may be potential field application this test. Materials method: One thousand three hundred seventy (70% males, mean age 64 ± 10 years), consecutively admitted for intensive rehabilitation, underwent 6MWT within...
Background: The physiological inhibitory control of glucagon-like Peptide 1 (GLP-1) on gastric emptying and the contribution this peptide in regulation food intake as a satiety factor suggest that impaired secretion and/or activity GLP-1 may be involved pathogenesis obesity. We investigated food-mediated well plasma dipeptidyl-peptidase IV (DPP-IV), enzyme responsible for rapid inactivation circulating peptide, morbidly obese patients, before after weight loss resulting from biliopancreatic...
Background— n-3 polyunsaturated fatty acids (n-3 PUFAs) exert antiarrhythmic effects and reduce sudden cardiac death. However, their role in the prevention of atrial fibrillation remains controversial. We aimed to determine effect PUFAs addition amiodarone a renin-angiotensin-aldosterone system inhibitor on maintenance sinus rhythm after direct current cardioversion patients with persistent fibrillation. Methods Results— conducted randomized, double-blind, placebo-controlled, parallel-arm...