- Cardiac Valve Diseases and Treatments
- Transplantation: Methods and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Viral Infections and Immunology Research
- Organ Transplantation Techniques and Outcomes
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Diabetes Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Cytomegalovirus and herpesvirus research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrest and Resuscitation
- Cardiovascular Effects of Exercise
- Pulmonary Hypertension Research and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Amyloidosis: Diagnosis, Treatment, Outcomes
Università Campus Bio-Medico
2018-2025
Campus Bio Medico University Hospital
2020-2025
IRCCS San Camillo Hospital
2024
Ospedale generale di zona San Camillo Treviso
2024
University of Bologna
2011-2023
Azienda Ospedaliera San Giovanni Addolorata
2023
University Hospital Foundation
2023
University Foundation
2023
Mayo Clinic in Arizona
2022
Délégation Provence et Corse
2021
Myocardial infarction (MI) can directly cause ischemic mitral regurgitation (IMR), which has been touted as an indicator of poor prognosis in acute and early phases after MI. However, the chronic post-MI phase, prognostic implications IMR presence degree are poorly defined.We analyzed 303 patients with previous (>16 days) Q-wave MI by ECG who underwent transthoracic echocardiography: 194 quantitatively assessed routine practice 109 without matched for baseline age (71+/-11 versus 70+/-9...
We analyzed the growth pattern of tumor masses and survival 39 asymptomatic Italian patients with a total 59 small (⩽ 5 cm in diameter) hepatocellular carcinomas arising from cirrhosis. The length observation period ranged 90 to 962 days, an average 364 ± 229 (mean S.D.). Doubling time 27.2 605.6 days S.D., 204.2 135; median = 171.6 days). Three different patterns were recognized: (a) tumors no or very slow initial (doubling > 200 days), 10 cases (37%); (b) declining rate over time, 9...
The optimal management of severe mitral valve regurgitation in patients without class I triggers (heart failure symptoms or left ventricular dysfunction) remains controversial part due to the poorly defined long-term consequences current strategies. In absence clinical trial data, analysis large multicenter registries is critical.To ascertain comparative effectiveness initial medical (nonsurgical observation) vs early surgery following diagnosis flail leaflets.The Mitral Regurgitation...
Hereditary transthyretin (TTR)-related amyloidosis (ATTR) is mainly considered a neurologic disease. We assessed the phenotypic and genotypic spectra of ATTR in Caucasian area evaluated prevalence, genetic background, disease profile cases with an exclusively cardiac phenotype, highlighting possible hints for differential diagnosis hypertrophic cardiomyopathy (HCM) senile systemic (SSA). In this Italian multicentre study, 186 patients were characterized at presentation. Thirty SSA 30...
Background: Mitral valve (MV) repair is preferred over replacement in clinical guidelines and an important determinant of the indication for surgery degenerative mitral regurgitation. However, level evidence supporting current recommendations low, recent data cast doubts on its validity era. Accordingly, aim present study was to analyze very long-term outcome after MV regurgitation with a flail leaflet. Methods: MIDA (Mitral Regurgitation International Database) multicenter registry...
Original Article from The New England Journal of Medicine — Polymerase Chain Reaction to Detect Hepatitis B Virus DNA and RNA Sequences in Primary Liver Cancers Patients Negative for Surface Antigen
To determine the frequency, predictors, and outcome implications of pulmonary hypertension (PH) diagnosed by Doppler echocardiography in a large cohort patients with homogenous diagnosis degenerative mitral regurgitation (MR) due to flail leaflets. The Mitral Regurgitation International DAtabase (MIDA) is registry including MR leaflets consecutively referred at tertiary centres Europe USA. Between 1987 2004, artery systolic pressure (PASP) was measured baseline 437 (age 67 ± 11 years; 66%...
Background: Mitral valve prolapse is more common in women than men, but men often have surgery for severe regurgitation. Objective: To compare morphology and outcomes of mitral women. Design: Retrospective cohort study. Setting: The Mayo Clinic, Rochester, Minnesota. Patients: 4461 3768 who received a diagnosis by echocardiography from 1989 to 1998 (896 Olmsted County residents 7333 referred patients). Measurements: characteristics (localization, leaflet thickening or flail, regurgitation),...
Background— Papillary muscle rupture (PMR) is an infrequent but catastrophic complication of acute myocardial infarction (MI). Although always considered, surgical treatment often denied because high operative mortality. Moreover, the effects surgery for PMR on long-term outcome, particularly compared with expected outcome after MI, are undefined. Methods and Results— Fifty-four consecutive patients (age, 70±8 years; 74% male) underwent mitral post-MI from January 1980 through December 2000....
Background— Although noninvasively detected myocardial fibrosis (MF) has clinical implications in hypertrophic cardiomyopathy, the extent, type, and distribution of ventricular MF have never been extensively pathologically characterized. We assessed overall amount, apex-to-base, circumferential, epicardial–endocardial distribution, pattern, type 30 transplanted hearts end-stage, cardiomyopathy. Methods Results— Visual morphometric histological analyses at basal, midventricular, apical levels...
Left atrium (LA) enlargement is common in organic mitral regurgitation (MR) and an emerging prognostic indicator. However, outcome implications of LA have not been analyzed the context routine clinical practice a multicenter study.The Mitral Regurgitation International DAtabase (MIDA) registry enrolls patients with MR due to flail leaflets, diagnosed practice, 5 US European centers. We investigated relation between diameter mortality under medical treatment after surgery 788 sinus rhythm...