A5104701385- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Clinical practice guidelines implementation
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced MRI Techniques and Applications
- S100 Proteins and Annexins
- Patient Satisfaction in Healthcare
- Acute Kidney Injury Research
- Peripheral Artery Disease Management
- Congenital Heart Disease Studies
- Intracranial Aneurysms: Treatment and Complications
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrest and Resuscitation
- Medical Imaging Techniques and Applications
- Cardiovascular Health and Disease Prevention
- Neurosurgical Procedures and Complications
- Advanced X-ray and CT Imaging
- Meta-analysis and systematic reviews
- Cardiac Imaging and Diagnostics
- Renal and Vascular Pathologies
University of Calgary
2024-2025
Foothills Medical Centre
2024-2025
Humanitas University
2024
University of British Columbia
2024
IRCCS Humanitas Research Hospital
2024
University of Zurich
2024
Kantonsspital Aarau
2024
BackgroundWhether the large effect size of endovascular thrombectomy (EVT) for stroke due to large-vessel occlusion applies medium-vessel is unclear.MethodsIn a multicenter, prospective, randomized, open-label trial with blinded outcome evaluation, we assigned patients acute ischemic who presented within 12 hours from time that they were last known be well and had favorable baseline noninvasive brain imaging receive EVT plus usual care or alone. The primary was modified Rankin scale score...
Introduction: CT perfusion maps (CTP) can estimate the ischemic core in acute stroke based on distinctive cerebral blood flow (CBF) thresholds. However, metabolic factors beyond influence tissue tolerance to ischemia and infarct growth rate. Hypothesis: We hypothesize that patients with lower hemoglobin higher glucose levels exhibit reduced resilience hypoperfusion will show larger underestimation volume (ICuV) compared other normal levels. Methods: Large vessel occlusion investigated...
BACKGROUND: Infarct growth rate is remarkably heterogeneous in acute ischemic stroke, reflecting diverse clinical-physiological phenotypes. We compared different methods of estimating infarct patients with stroke undergoing thrombectomy using multimodal computed tomography (CT) imaging. METHODS: Secondary analysis the international ESCAPE-NA1 trial (Efficacy and Safety Nerinetide for Treatment Acute Ischemic Stroke) which evaluated effect nerinetide large vessel occlusion thrombectomy. was...
Background We investigate whether the National Institutes of Health Stroke Scale (NIHSS) at 24 hours could serve as a primary outcome in acute ischemic stroke trials, and combining 90‐day modified Rankin (mRS) 24‐hour NIHSS hierarchical enhance detection treatment effect, using endovascular (EVT) an exemplary study intervention. Methods This was post hoc analysis pooled data from 7 randomized EVT trials. Twenty‐four‐hour surrogate for mRS assessed causal mediation model. A 7‐point ordinal...
Background Better reperfusion status results in smaller infarct volumes and better outcomes after thrombectomy. However, if large tissue are already infarcted at baseline, might also increase the risk of intracranial hemorrhage. This study aims to investigate interaction between status, baseline ischemic changes, hemorrhage following Methods Retrospective analysis ESCAPE-NA1 randomized trial. Unadjusted adjusted logistic regression models were used estimate associations Alberta Stroke...
CT perfusion (CTP) maps can estimate the ischemic core in acute stroke based on distinctive cerebral blood flow thresholds. However, metabolic factors beyond influence tissue tolerance to ischemia and infarct growth rate. Underestimating volume (ICV) might result overestimating salvageable and, consequently, potential clinical benefits of reperfusion therapies. We aim evaluate whether baseline hemoglobin glucose levels accuracy CTP ICV estimations.
Abstract Background: Contrast-induced encephalopathy (CIE) is a rare adverse event linked to intravascular use of iodine-containing contrast media. The prevalence CIE could increase in the future due growing numbers endovascular procedures. We provide insights from case series 7 patients. Methods: Cases 3 centers were collected based on existing academic collaborations, and key factors extracted illustrate development management CIE. Results: In our retrospective case-series analysis cases...
The endovascular approach has emerged as standard therapy for many intracranial aneurysms (IAs) to prevent hemorrhage, yet its long-term durability varies considerably. aim of this study was evaluate the safety and effectiveness an initially deliberate regarding IA hemorrhage rates over a follow-up period.