- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Infectious Diseases and Tuberculosis
- Meningioma and schwannoma management
- Cerebrospinal fluid and hydrocephalus
- Moyamoya disease diagnosis and treatment
- Orthopedic Infections and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Teratomas and Epidermoid Cysts
- Parasitic infections in humans and animals
- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Pituitary Gland Disorders and Treatments
- Gastrointestinal disorders and treatments
- Advanced MRI Techniques and Applications
- Diagnosis and treatment of tuberculosis
- Head and Neck Surgical Oncology
- MRI in cancer diagnosis
- Spinal Dysraphism and Malformations
- Aortic aneurysm repair treatments
- Traumatic Ocular and Foreign Body Injuries
- Spinal Fractures and Fixation Techniques
Leeds Teaching Hospitals NHS Trust
2016-2025
Leeds General Infirmary
2012-2025
University of Manchester
2002-2025
National Health Service
2015
St James's University Hospital
2014
Lancashire Teaching Hospitals NHS Foundation Trust
2010
Royal Preston Hospital
2010
Salford Royal Hospital
2005
King Edward Memorial Hospital
1998-2003
King Edward Memorial Hospital Research Centre
1997-2001
BackgroundWhether the large effect size of endovascular thrombectomy (EVT) for stroke due to large-vessel occlusion applies medium-vessel is unclear.MethodsIn a multicenter, prospective, randomized, open-label trial with blinded outcome evaluation, we assigned patients acute ischemic who presented within 12 hours from time that they were last known be well and had favorable baseline noninvasive brain imaging receive EVT plus usual care or alone. The primary was modified Rankin scale score...
Use of the WEB intra-aneurysmal flow-disruption device in unruptured wide-neck bifurcation aneurysms has proven safety and efficacy. However, ruptured are underrepresented existing studies. This retrospective multicenter study describes use patients with a intracranial aneurysm.Ten centers contributed to this study. Clinical procedural data 47 52 were analyzed retrospectively together follow-up angiographies.There 37 anterior 15 posterior circulation neck size ≥4 mm 49 (94%) aneurysms; 45...
Intrasaccular devices have broadened treatment options for wide necked aneurysms. This study presents the preliminary experience with Artisse 2.0 device. Innovative NeurovaScular Product SurveIllance REgistry (INSPIRE) is a non-randomized, multicenter, real world clinical arms aneurysms (INSPIRE-A) and acute ischemic stroke (INSPIRE-S). interim analysis included 87 patients enrolled from November 2022 to April 2024 in INSPIRE-A cohort across 16 Europoean centers. Procedures followed standard...
Background and purpose Wide-necked bifurcation aneurysms pose a significant challenge to the treating clinician. The Contour Neurovascular System embolization device is novel tool for treatment of such intracranial aneurysms. We report on our experience with this device. Methods Prospective clinical radiological data were collected all patients treated at center. All an elective basis. Results have 11 successfully date. women mean (SD) age 65.0 (6.4) years. In total, four basilar tip, two...
Background Intrasaccular devices have become increasingly popular in the treatment of cerebral aneurysms, particularly at bifurcation. Here we evaluate Contour Neurovascular System, an intrasaccular device for endovascular a multicenter cohort study, largest to best our knowledge. Methods Consecutive patients with intracranial aneurysms treated System between February 2017 and October 2022 10 European neurovascular centers were prospectively collected retrospectively reviewed. Patient...
To correlate imaging abnormalities, clinical features, and postmortem findings in patients with proved cerebral malaria.Twenty-one aged 17-50 years malaria consented to undergo transverse nonenhanced (10-mm sections) contrast material-enhanced (8-mm sections posterior fossa 10-mm supratentorial region) CT on admission (n = 21) day 10 6), thin (5 mm) obtained the area of abnormality. All scans were evaluated for diffuse edema, focal parenchymal hemorrhage. categorized as normal, edema...
<h3>BACKGROUND AND PURPOSE:</h3> The safety and efficiency of the dual-layer Woven EndoBridge (WEB) device has already been published. However, this international multicenter study sought to evaluate single-layer devices, which are newest generation WEB intrasaccular flow-disrupter family. They have designed offer smaller-sized devices with a lower profile optimize navigability delivery, may, in turn, broaden their range use. <h3>MATERIALS METHODS:</h3> Data from all consecutive patients...
Study of magnetic resonance imaging (MRI) tuberculosis spine to determine the incidence and features isolated tuberculous involvement posterior spinal elements.To describe MRI findings in patients with elements.Spinal is more common eastern countries than western world. Recently, there has been a renewed interest west because its re-emergence, especially immunocompromised (e.g., HIV). The classic radiologic picture "two vertebral disease destruction intervertebral disc" easily recognized...
OBJECTIVE The Woven Endobridge (WEB) device has been in clinical use for the treatment of brain aneurysms past 4 years. Observational studies to assess outcome and related complications have published. Clear evidence is required better understand safety profile WEB device. authors here present a multicenter series that provides detailed analysis focused on patient selection, procedural events, technical issues treated patients throughout United Kingdom (UK). METHODS A nationwide...
Intrasaccular flow disruption has become established for the treatment of wide necked and bifurcation aneurysms. The most successful current devices are WEB (Microvention) Contour (Stryker). Artisse (Medtronic) is a novel intrasaccular device designed to treat variety aneurysm morphologies. first generation was used in clinical trials 2016.1 This now been significantly modified, this video discusses second (video 1). features dual layer, 72 wire mesh basket. It includes an atraumatic,...
OBJECTIVE The goal of this study was to assess the safety and feasibility PulseRider, a novel endovascular stent, in treatment intracranial bifurcation aneurysms with wide necks. authors present initial results first 10 cases which PulseRider device used. METHODS Patients whose were intended be treated at 2 institutions United Kingdom identified prospectively. Patient demographics, procedural details, immediate neurological clinical status, angiographic outcomes 6-month imaging follow-up...
Thrombosis is a biological response closely related to intracranial aneurysms, and the formation of thrombi inside aneurysm an important determinant outcome after endovascular therapy. As regulation thrombosis immensely complicated mechanisms governing thrombus are not fully understood, mathematical computational modeling has been increasingly used gain insight into over last 30 years. To have robust model for possible clinical use in future, it essential assess model's reliability through...
Abstract Objectives To create a nationwide consortium to gather all the data related advanced devices used for aneurysm treatment and conduct pragmatic real-world studies despite variations amongst centres. The strength of this study will be in pooling less commonly recent where there is evidence. prospective retrospective initial recruitment figure expected around 5000 patients. Methods assess how endovascular techniques vary among different UK centres we illustrate results surveys that...
Fetus in fetu is a rare abnormality secondary to the abnormal embryogenesis diamniotic, monochorionic pregnancy. It an unusual condition which vertebrate fetus enclosed within abdomen of normally developing fetus. Presented are computed tomographic findings two cases imaging were diagnostic this entity.