A5068976929- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Advanced X-ray and CT Imaging
- Cardiac tumors and thrombi
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Pericarditis and Cardiac Tamponade
- Cardiovascular Health and Disease Prevention
- Coronary Artery Anomalies
- Parasite Biology and Host Interactions
- Cerebrovascular and Carotid Artery Diseases
- Cardiac pacing and defibrillation studies
- Radiation Dose and Imaging
- Lung Cancer Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Pulmonary Hypertension Research and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Myasthenia Gravis and Thymoma
- Aortic Disease and Treatment Approaches
- Medical Imaging Techniques and Applications
University Hospital Southampton NHS Foundation Trust
2013-2024
Essex Cardiothoracic Centre
2012-2021
University of Hawaiʻi at Mānoa
2020
National Health Service
2020
Southampton General Hospital
2000-2016
University of Southampton
2010-2016
University of Leicester
2015-2016
Glenfield Hospital
2016
University of Leeds
2016
Royal Brompton & Harefield NHS Foundation Trust
2016
There is no licensed treatment for non-alcoholic fatty liver disease (NAFLD), a condition that increases risk of chronic disease, type 2 diabetes and cardiovascular disease. We tested whether 15-18 months with docosahexaenoic acid (DHA) plus eicosapentaenoic (EPA) (Omacor/Lovaza) (4 g/day) decreased fat improved two histologically-validated fibrosis biomarker scores (primary outcomes). Patients NAFLD were randomised in double blind placebo-controlled trial [DHA+EPA(n=51), placebo(n=52)]....
Characterization of sudden cardiac death (SCD) risk remains a challenge in the application implantable cardioverter-defibrillator (ICD) therapy. Late gadolinium enhancement MRI (LGE-CMR) can accurately identify myocardial scar. We performed retrospective, single-center observational study to evaluate association between extent and distribution left ventricular scar, quantified using LGE-CMR, burden arrhythmias patients with coronary artery disease ICDs.All included (2006 2009) had undergone...
To investigate the pharmacology and potential clinical utility of splenic switch-off to identify understress in adenosine perfusion cardiac magnetic resonance (MR) imaging.Splenic was assessed MR examinations from 100 patients (mean age, 62 years [age range, 18-87 years]) by using three stress agents (adenosine, dobutamine, regadenoson) different institutions, with appropriate ethical permissions. In addition, negative images Clinical Evaluation Imaging Coronary Heart Disease (CE-MARC) trial...
Instrument-assisted soft tissue mobilization and massage therapy are manual techniques that claim to increase blood flow treated areas, yet no data on these available. This study sought compare the effects of Graston Technique(®) (GT) calf flow, using skin temperature measures lower leg.Single-blinded prospective, longitudinal, controlled, repeated-measures design.Research laboratory.Twenty-eight participants (mean age, 23±3 years; 14 men women; mean girth, 39.5±4.31 cm; skinfold thickness,...
Cardiac computed tomography (CT) and cardiac magnetic resonance imaging (MRI) are routine radiological examinations for diagnosis prognosis of disease. The expected growth in radiology the coming years will exceed current scanner capacity trained workforce. European Society Cardiovascular Radiology (ESCR) focuses on supporting strengthening role cross-sectional Europe from a multi-modality perspective. Together with (ESR), ESCR has taken initiative to describe status of, vision for, required...
Complete revascularization may improve outcomes compared with an infarct-related artery (IRA)-only strategy in patients being treated primary percutaneous coronary intervention (PPCI) who have multivessel disease presenting ST-segment elevation myocardial infarction (STEMI). However, there is concern that non-IRA PCI cause additional (MI). This study sought to determine whether in-hospital complete was associated increased total infarct size IRA-only strategy. multicenter prospective,...
The European Society of Cardiovascular Radiology (ESCR) is the specialist society cardiac and vascular imaging. This society's highest priority continuous improvement, development, standardization education, training, best medical practice, based on experience evidence. present intra-society consensus existing scientific evidence individual members ESCR writing group carotid diseases, guidelines committee, executive committee ESCR. recommendations published herein reflect evidence-based...
The relatively high mortality in patients with pulmonary atresia and intact ventricular septum may be related to the presence of significant coronary arterial anomalies. This retrospective review cineangiocardiograms was undertaken further elucidate types variety such abnormalities, assess their effect on postoperative survival.Details regarding anatomy abnormalities were assessed 116 patients. We noted site severity lesions, fistulous communications from right ventricle arteries, assessing...
Giant cell myocarditis (GCM) typically causes fulminant heart failure, arrhythmias, or block, necessitating aggressive immunosuppression, ventricular assist device insertion, cardiac transplantation. We describe a novel variant of GCM, primarily involving the atria, that displays distinctive clinical features and follows more benign course than GCM.We identified 6 patients (median age 67.5 years, 4 male) with atrial GCM in our pathology consultation practices from 2010 to 2012. Clinical...
Third-generation P2Y12 antagonists (prasugrel and ticagrelor) are recommended in guidelines on ST-segment elevation myocardial infarction. Mechanisms translating their more potent antiplatelet activity into improved clinical outcomes versus the second-generation antagonist clopidogrel unclear. The aim of this post hoc analysis Complete Versus Lesion-Only PRImary PCI Trial-CMR (CvLPRIT-CMR) substudy was to assess whether prasugrel ticagrelor were associated with reduced infarct size compared...
The European Society of Cardiovascular Radiology (ESCR) is the specialist society cardiac and vascular imaging. This society's highest priority continuous improvement, development, standardization education, training, best medical practice, based on experience evidence. present intra-society consensus existing scientific evidence individual members ESCR writing group carotid diseases, guidelines committee, executive committee ESCR. recommendations published herein reflect evidence-based...
Endobronchial ultrasound (EBUS) allows identification of airway wall structures and could potentially be utilised for in vivo studies thickening asthma. The present study investigated whether inflation the fluid-filled balloon sheath over transducer (necessary to provide sonic coupling with wall) influenced vitro measurements. In comparability EBUS high resolution computed tomography scanning (HRCT), an established method measuring thickness, was determined control subjects. diameter...
The purpose of this study was to assess the outcome cardiac MRI (CMRI) with late gadolinium enhancement (LGE) at outpatient follow-up in a consecutive series patients troponin-positive chest pain but unobstructed coronary arteries index admission.The group comprised 91 who presented our institution pain, elevated troponin I and on angiography. All underwent an CMRI LGE imaging order establish definitive diagnosis.The average time from angiography LGE-CMRI 2 months. 73% had no abnormality...