Luca Saba

ORCID: 0000-0003-2870-3771
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About
Contact & Profiles
Research Areas
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiovascular Health and Disease Prevention
  • Acute Ischemic Stroke Management
  • Cardiac Imaging and Diagnostics
  • Advanced X-ray and CT Imaging
  • Radiomics and Machine Learning in Medical Imaging
  • Coronary Interventions and Diagnostics
  • Intracranial Aneurysms: Treatment and Complications
  • Cardiovascular Disease and Adiposity
  • Cardiovascular Function and Risk Factors
  • Advanced MRI Techniques and Applications
  • Radiation Dose and Imaging
  • Endometriosis Research and Treatment
  • COVID-19 diagnosis using AI
  • Ovarian cancer diagnosis and treatment
  • Uterine Myomas and Treatments
  • AI in cancer detection
  • Endometrial and Cervical Cancer Treatments
  • Medical Imaging Techniques and Applications
  • Functional Brain Connectivity Studies
  • MRI in cancer diagnosis
  • Lung Cancer Diagnosis and Treatment
  • Liver Disease Diagnosis and Treatment
  • Artificial Intelligence in Healthcare and Education
  • Hepatocellular Carcinoma Treatment and Prognosis

University of Cagliari
2016-2025

Azienda Ospedaliero-Universitaria Cagliari
2016-2025

Nini Hospital
2025

University of Bologna
2017-2025

KU Leuven
2025

Ludwig-Maximilians-Universität München
2025

Mayo Clinic
2024-2025

Erasmus MC
2025

University of Padua
2025

University of Maryland, Baltimore
2025

In the diagnosis of obstructive coronary artery disease (CAD), computed tomography (CT) is an accurate, noninvasive alternative to invasive angiography (ICA). However, comparative effectiveness CT and ICA in management CAD reduce frequency major adverse cardiovascular events uncertain.We conducted a pragmatic, randomized trial comparing with as initial diagnostic imaging strategies for guiding treatment patients stable chest pain who had intermediate pretest probability were referred at one...

10.1056/nejmoa2200963 article EN New England Journal of Medicine 2022-03-04

<h3>SUMMARY:</h3> Identification of carotid artery atherosclerosis is conventionally based on measurements luminal stenosis and surface irregularities using in vivo imaging techniques including sonography, CT MR angiography, digital subtraction angiography. However, histopathologic studies demonstrate considerable differences between plaques with identical degrees indicate that certain plaque features are associated increased risk for ischemic events. The ability to look beyond the lumen...

10.3174/ajnr.a5488 article EN cc-by American Journal of Neuroradiology 2018-01-11

One in six ischaemic stroke patients has an embolic of undetermined source (ESUS), defined as a with unclear aetiology despite recommended diagnostic evaluation. The overall cardiovascular risk ESUS is high and it important to optimize strategies prevent recurrent other events. aim clinicians when confronted patient not only but also any medical condition identify the actual cause amongst list potential differential diagnoses, order secondary prevention. However, specifically ESUS, this may...

10.1093/eurheartj/ehae150 article EN cc-by European Heart Journal 2024-04-30

Abstract The introduction of large language models (LLMs) into clinical practice promises to improve patient education and empowerment, thereby personalizing medical care broadening access knowledge. Despite the popularity LLMs, there is a significant gap in systematized information on their use care. Therefore, this systematic review aims synthesize current applications limitations LLMs using data-driven convergent synthesis approach. We searched 5 databases for qualitative, quantitative,...

10.1101/2024.03.04.24303733 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2024-03-05

Importance Rapid digitalization of health care and a dearth digital education for medical students junior physicians worldwide means there is an imperative more training in this dynamic evolving field. Objective To develop evidence-informed, consensus-guided, adaptable competencies framework the design development curricula institutions globally. Evidence Review A core group was assembled to oversee Digital Health Competencies Medical Education (DECODE) framework. First, initial list created...

10.1001/jamanetworkopen.2024.53131 article EN cc-by-nc-nd JAMA Network Open 2025-01-31

BACKGROUND AND PURPOSE: Ulceration is a severe complication of carotid plaque. The purpose this study was to evaluate the role and diagnostic efficacy multidetector row CT angiography (MDCTA) ultrasound (US) echo color Doppler (US-ECD) in patients with plaque complicated by ulceration through comparison surgical observation. MATERIALS METHODS: From January 2004 October 2005, 237 patients, for total 474 arteries, studied at first US, were analyzed using angiography. A 103 underwent...

10.3174/ajnr.a0486 article EN cc-by American Journal of Neuroradiology 2007-06-01

The aim of this paper is to describe a novel and completely automated technique for carotid artery (CA) recognition, far (distal) wall segmentation, intima-media thickness (IMT) measurement, which strong clinical tool risk assessment cardiovascular diseases. architecture multiresolution edge snapper (CAMES) consists the following two stages: 1) CA recognition based on combination scale-space statistical classification in framework 2) segmentation lumen-intima (LI) media-adventitia (MA)...

10.1109/tip.2011.2169270 article EN IEEE Transactions on Image Processing 2011-09-28
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