Imre Benedek
A5088418144- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Cardiac Fibrosis and Remodeling
- Coronary Artery Anomalies
- Mesenchymal stem cell research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Peripheral Artery Disease Management
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Lipoproteins and Cardiovascular Health
- Vascular anomalies and interventions
- Cardiovascular Health and Disease Prevention
- Cardiovascular Issues in Pregnancy
- Cardiac Health and Mental Health
- Biomarkers in Disease Mechanisms
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș
2016-2025
Spitalul Clinic Judetean de Urgenta Târgu Mureş
2013-2025
Charité - Universitätsmedizin Berlin
2024
Clinical Emergency Hospital Bucharest
2018-2023
University of Copenhagen
2022
Semmelweis University
2022
Instituto Cajal
2022
Weatherford College
2020-2021
Impact
2020
Spitalul Clinic Judetean Mures
2008-2019
In the diagnosis of obstructive coronary artery disease (CAD), computed tomography (CT) is an accurate, noninvasive alternative to invasive angiography (ICA). However, comparative effectiveness CT and ICA in management CAD reduce frequency major adverse cardiovascular events uncertain.We conducted a pragmatic, randomized trial comparing with as initial diagnostic imaging strategies for guiding treatment patients stable chest pain who had intermediate pretest probability were referred at one...
Background Coronary artery calcium (CAC) has prognostic value for major adverse cardiovascular events (MACE) in asymptomatic individuals, whereas its role symptomatic patients is less clear. Purpose To assess the of CAC scoring MACE participants with stable chest pain initially referred invasive coronary angiography (ICA). Materials and Methods This prespecified subgroup analysis from Diagnostic Imaging Strategies Patients With Stable Chest Pain Intermediate Risk Artery Disease (DISCHARGE)...
Computed tomography angiography (CTA) has validated the use of pericoronary adipose tissue (PCAT) attenuation as a credible indicator coronary inflammation, playing crucial role in artery disease (CAD). This study aimed to evaluate long-term effects high-dose statins on PCAT at lesion sites and changes plaque distribution. Our prospective observational included 52 patients (mean age 60.43) with chest pain, low-to-intermediate likelihood CAD, who had documented atheromatous through CTA,...
Inflammation is a key factor in the development of atherosclerosis, disease characterized by buildup plaque arteries. COVID-19 infection known to cause systemic inflammation, but its impact on local vulnerability unclear. Our study aimed investigate coronary artery (CAD) patients who underwent computed tomography angiography (CCTA) for chest pain early stages after infection, using an AI-powered solution called CaRi-Heart®. The included 158 (mean age was 61.63 ± 10.14 years) with angina and...
To assess the comparative effectiveness of computed tomography and invasive coronary angiography in women men with stable chest pain suspected to be caused by artery disease. Prospective, multicentre, randomised pragmatic trial. Hospitals at 26 sites 16 European countries. 2002 (56.2%) 1559 (43.8%) (total 3561 patients) disease referred for on basis a pre-test probability obstructive 10-60%. Both were 1:1 (with stratification gender centre) strategy either or as initial diagnostic test (1019...
The purpose of this study was to demonstrate the relationship between presence and amount a low-density core (LDC) with CT density < 30 Hounsfield units (HU) by coronary computed tomography angiography (CCTA) IVUS-derived markers vulnerability in culprit lesions (CL) patients acute syndromes (ACS).In 43 ACS, 105 plaques were scanned using CCTA IVUS for quantitative qualitative assessment markers.The low attenuation plaque (LAP) identified 67.4% CL 29.03% non-CL (P = 0.0001). LDC > 6.0 mm3...
(1) The link between periodontal disease (PD) and acute coronary syndromes (ACSs) is predominantly attributed to the atherosclerotic process, mediated by systemic inflammation. However, correlation severity of PD, characterized presence pathogens, inflammation in patients with ACS remains inadequately clarified. (2) This study aims assess association PD inflammatory biomarkers, along lipid profiles, ACS. (3) In total, 42 concomitant were divided into two groups based on pathogens belonging...
Importance The effect of computed tomography (CT) vs invasive coronary angiography (ICA) on health status outcomes is unknown. Objective To evaluate CT and ICA first-test strategies quality life (QOL) angina. Design, Setting, Participants Diagnostic Imaging Strategies for Patients With Stable Chest Pain Intermediate Risk Coronary Artery Disease (DISCHARGE) randomized clinical trial, conducted between October 2015 April 2019 in 26 European centers, followed up patients with stable chest pain...
Health-related quality of life (HRQoL) is impaired in patients with stable angina but often present other forms chest pain. The aim this study was to compare the pre-diagnostic HRQoL suspected coronary artery disease (CAD) according type, gender, and presence obstructive CAD. From pilot for European DISCHARGE trial, we analysed data from 24 sites including 1263 (45.9% women, 61.1 ± 11.3 years) who were clinically referred invasive angiography (ICA; 617 patients) or computed tomography (CTA;...
Abstract Introduction The pericoronary fat attenuation index (FAI) is an emerging computed tomography-derived marker for measuring vascular inflammation at coronary vessels. It holds prognostic significance major cardiovascular events and enhances cardiac risk assessment, complementing traditional factors artery calcium scores. However, the impact of local circulation on development in right versus left arteries has not been clearly understood. Objective This study aimed to investigate...
During the past 10 years, health of people in Eastern Europe and former Soviet Union has undergone changes very different from patterns seen their Western counterparts. Mortality cardiovascular disease been decreasing continuously USA many European countries, but it increased or remained unchanged states Europe. Analysis this phenomenon hindered by insufficient information. The International Registry Acute Coronary Syndromes registry study Transitional Countries (ISACS-TC) is both a...
The present study aimed to investigate the association between apolipoprotein B (Apo B) and classical features associated with clinical or subclinical atherosclerosis. A total of 811 adult patients from general Romanian population, included in national SEPHAR registry on hypertension, were divided into two groups based Apo value (low versus high a cut-off established at 130 mg/dL) subsequently four subgroups according cut-offs recommended by 2021 ESC Guidelines Cardiovascular Disease...
Aim The aim of the present study was to assess influence nutritional status, as expressed by Controlling Nutritional Status (CONUT) and Geriatric Risk Index (GNRI) scores, on inflammatory response following acute myocardial infarction (AMI) impact an altered status increased systemic inflammation immediate evolution AMI. Methods This observational prospective in which we used CONUT score GNRI 86 consecutive patients with AMI receiving primary revascularisation, divided into a well‐nourished...