Richard Marigold
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- COVID-19 Clinical Research Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Epilepsy research and treatment
- Long-Term Effects of COVID-19
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Atrial Fibrillation Management and Outcomes
- Peripheral Artery Disease Management
- Radiation Therapy and Dosimetry
- Infectious Encephalopathies and Encephalitis
- Cerebrovascular and genetic disorders
- Cardiovascular Syncope and Autonomic Disorders
- Neurological and metabolic disorders
- Cerebral Venous Sinus Thrombosis
- COVID-19 and healthcare impacts
- Heparin-Induced Thrombocytopenia and Thrombosis
- S100 Proteins and Annexins
- Botulinum Toxin and Related Neurological Disorders
- Heart Rate Variability and Autonomic Control
- Vagus Nerve Stimulation Research
- Vascular Malformations Diagnosis and Treatment
University Hospital Southampton NHS Foundation Trust
2020-2025
Southampton General Hospital
2024
University of Southampton
2024
NIHR Southampton Biomedical Research Centre
2024
Campbell Collaboration
2021
Royal Bournemouth Hospital
2010-2013
BackgroundWhether the large effect size of endovascular thrombectomy (EVT) for stroke due to large-vessel occlusion applies medium-vessel is unclear.MethodsIn a multicenter, prospective, randomized, open-label trial with blinded outcome evaluation, we assigned patients acute ischemic who presented within 12 hours from time that they were last known be well and had favorable baseline noninvasive brain imaging receive EVT plus usual care or alone. The primary was modified Rankin scale score...
Objective We set out to determine which characteristics and outcomes of stroke are associated with COVID-19. Methods This case-control study included patients admitted 13 hospitals in England Scotland between 9 March 5 July 2020. collected data on 86 strokes (81 ischaemic intracerebral haemorrhages) evidence COVID-19 at the time onset (cases). They were compared 1384 (1193 191 during same period who never had (controls). In addition, whole group admissions, including another 37 appeared have...
Background: Tenecteplase has potential benefits over alteplase, the standard agent for intravenous thrombolysis in acute ischaemic stroke, because it is administered as a single bolus and might have superior efficacy. ATTEST-2 investigated whether tenecteplase 0.25mg/kg was non-inferior or to alteplase 0.9mg/kg within 4.5h of onset.Methods: We undertook prospective, multicentre, randomised parallel group open label trial with blinded end-point evaluation previously independent adults...
Summary The autonomic nervous system comprises the sympathetic, parasympathetic and enteric systems plays an integral role in homeostasis. This includes cardiovascular temperature control, glucose metabolism, gastrointestinal reproductive function increasing evidence to support its involvement inflammatory response infection cancer. Ageing is associated with dysfunction, many clinical syndromes older adults are due inadequate responses physiological stressors. aim of this review explore...
La hemorragia subaracnoidea puede dar lugar a convulsiones agudas y largo plazo. Existen dudas con respecto la administración de fármacos antiepilépticos (FAE) para prevención primaria secundaria las después y, actualmente, no hay consenso acerca del tratamiento. Evaluar los efectos FAE subaracnoidea. Se hicieron búsquedas en el Registro Especializado Grupo Cochrane Epilepsia (Cochrane Epilepsy Group), Central Ensayos Controlados Register of Controlled Trials) (CENTRAL) (2013, número 1) The...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
This book is unique in that, for the first time, most aspects of nuclear medicine relation to liver and spleen are drawn together between two covers. As editor states, technical details kept a minimum whereas basic principles tests involved, their indications interpretations emphasized.