Vítor Mendes Pereira
A5083818499- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Peripheral Artery Disease Management
- Cerebral Venous Sinus Thrombosis
- Moyamoya disease diagnosis and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Meningioma and schwannoma management
- Aortic aneurysm repair treatments
- Spinal Fractures and Fixation Techniques
- Cardiovascular Health and Disease Prevention
- Aortic Disease and Treatment Approaches
- Cerebrospinal fluid and hydrocephalus
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Vascular Procedures and Complications
- Surgical Simulation and Training
- Central Venous Catheters and Hemodialysis
- Radiation Dose and Imaging
- Antiplatelet Therapy and Cardiovascular Diseases
University of Toronto
2016-2025
St. Michael's Hospital
2017-2025
Federal Emergency Management Agency
2025
Centro Universitário Católico Salesiano Auxilium
2025
Universidade de Marília
2025
Toronto Western Hospital
2015-2024
University Health Network
2015-2024
St Michaels Hospital
2023-2024
Brigham and Women's Hospital
2024
Massachusetts General Hospital
2016-2024
Among patients with acute ischemic stroke due to occlusions in the proximal anterior intracranial circulation, less than 40% regain functional independence when treated intravenous tissue plasminogen activator (t-PA) alone. Thrombectomy use of a stent retriever, addition t-PA, increases reperfusion rates and may improve long-term outcome.
The effect of endovascular thrombectomy that is performed more than 6 hours after the onset ischemic stroke uncertain. Patients with a clinical deficit disproportionately severe relative to infarct volume may benefit from late thrombectomy.
Trials of the efficacy and safety endovascular thrombectomy in patients with large ischemic strokes have been carried out limited populations. Download a PDF Research Summary. We performed prospective, randomized, open-label, adaptive, international trial involving stroke due to occlusion internal carotid artery or first segment middle cerebral assess within 24 hours after onset. Patients had ischemic-core volume, defined as an Alberta Stroke Program Early Computed Tomography Score 3 5...
The role of endovascular therapy for acute stroke with a large infarction has not been extensively studied in differing populations. Download PDF the Research Summary. We conducted multicenter, prospective, open-label, randomized trial China involving patients large-vessel occlusion anterior circulation and an Alberta Stroke Program Early Computed Tomography Score 3 to 5 (range, 0 10, lower values indicating larger infarction) or infarct-core volume 70 100 ml. Patients were randomly assigned...
Sporadic arteriovenous malformations of the brain, which are morphologically abnormal connections between arteries and veins in brain vasculature, a leading cause hemorrhagic stroke young adults children. The genetic this rare focal disorder is unknown.
We endeavored to develop an unruptured intracranial aneurysm (UIA) treatment score (UIATS) model that includes and quantifies key factors involved in clinical decision-making the management of UIAs assess agreement for this among specialists UIA research.
Background and Purpose— Mechanical thrombectomy using stent retriever devices have been advocated to increase revascularization in intracranial vessel occlusion. We present the results of a large prospective study on use Solitaire Flow Restoration patients with acute ischemic stroke. Methods— Thrombectomy for Acute Revascularization was an international, multicenter, prospective, single-arm anterior circulation strokes treated within 8 hours symptom onset. Strict criteria site selection were...
Purpose To study the relationship between functional independence and time to reperfusion in Solitaire with Intention for Thrombectomy as Primary Endovascular Treatment Acute Ischemic Stroke (SWIFT PRIME) trial patients disabling acute ischemic stroke who underwent endovascular therapy plus intravenous tissue plasminogen activator (tPA) administration versus tPA alone investigate variables that affect spent during discrete steps. Materials Methods Data were analyzed from SWIFT PRIME trial, a...
Rationale Early reperfusion in patients experiencing acute ischemic stroke is critical, especially for with large vessel occlusion who have poor prognosis without revascularization. Solitaire™ stent retriever devices been shown to immediately restore vascular perfusion safely, rapidly, and effectively occlusions. Aim The aim of the study was demonstrate that, among vessel, anterior circulation received intravenous tissue plasminogen activator, treatment Solitaire revascularization reduces...
Background Preliminary clinical studies on the safety and efficacy of pipeline embolization device (PED) for treatment small/medium aneurysms have demonstrated high occlusion rates with low complications. Objective To evaluate effectiveness PED wide necked small medium intracranial aneurysms. Methods PREMIER is a prospective, multicenter, single arm trial. Patients were treated unruptured aneurysms, measuring ≤12 mm along internal carotid artery or vertebral artery, between July 2014...
<h3>Importance</h3> Mechanical thrombectomy (MT) improves clinical outcomes in patients with acute ischemic stroke (AIS) caused by a large vessel occlusion. However, it is not known whether intravenous thrombolysis (IVT) of added benefit undergoing MT. <h3>Objective</h3> To examine treatment IVT before MT stent retriever beneficial <h3>Design, Setting, and Participants</h3> This post hoc analysis used data from 291 treated included 2 large, multicenter, prospective trials that evaluated for...
Rationale Efficacy of mechanical thrombectomy for acute stroke due to large vessel occlusion initiated beyond 6 h time last seen well has not been demonstrated in randomized trials. Aim To establish whether subjects considered have substantial areas salvageable brain based on age-adjusted clinical core mismatch who can undergo endovascular treatment within 6–24 from (TLSW) better outcomes at three months compared treated with standard medical therapy alone. Age-adjusted is defined by age...
<b><i>Background and Objective:</i></b> Few prospective studies exist evaluating the safety efficacy of Pipeline Embolization Device (PED) in treatment intracranial aneurysms. The Aneurysm Study In an observational Registry (ASPIRe) study prospectively analyzed rates complete aneurysm occlusion neurologic adverse events following PED <b><i>Materials Methods:</i></b> We performed a multicenter patients with unruptured aneurysms treated PED....
Importance Whether endovascular thrombectomy (EVT) efficacy for patients with acute ischemic stroke and large cores varies depending on the extent of injury is uncertain. Objective To describe relationship between imaging estimates irreversibly injured brain (core) at-risk regions (mismatch) clinical outcomes EVT treatment effect. Design, Setting, Participants An exploratory analysis SELECT2 trial, which randomized 352 adults (18-85 years) due to occlusion internal carotid or middle cerebral...
Mechanical thrombectomy (MT) has revolutionized the treatment of acute ischemic stroke (AIS) due to large vessel occlusion (LVO), but its efficacy and safety in medium (MeVO) remain less explored. This multicenter, retrospective study aims investigate incidence clinical outcomes perforations (confirmed by extravasation during an angiographic series) MT for AIS caused MeVO.
Acute ischemic stroke (AIS) caused by distal medium vessel occlusions (DMVOs) represents a significant proportion of overall cases. While intravenous thrombolysis (IVT) has been primary treatment, advancements in endovascular procedures have led to increased use mechanical thrombectomy (MT) DMVO patients. However, symptomatic intracerebral hemorrhage (sICH) remains critical complication AIS, particularly after undergoing intervention. This study aims identify factors associated with sICH patients MT.
Although previous trials have established the efficacy and safety of endovascular thrombectomy (EVT) in large ischemic core strokes, most them excluded patients with extracranial internal carotid artery (e-ICA) occlusion. We aimed to compare outcomes e-ICA occlusion infarcts treated EVT vs medical management (MM). This was a secondary analysis SELECT2 trial, randomized controlled trial conducted at 31 international sites. Adult proximal intracranial anterior circulation defined as Alberta...