- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Nanoplatforms for cancer theranostics
- Advanced biosensing and bioanalysis techniques
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- RNA modifications and cancer
- Nanoparticle-Based Drug Delivery
- Analytical Chemistry and Chromatography
- Radiopharmaceutical Chemistry and Applications
- Multi-Criteria Decision Making
- RNA Interference and Gene Delivery
- Advanced Photocatalysis Techniques
- Seismic Imaging and Inversion Techniques
- 2D Materials and Applications
- Cell Adhesion Molecules Research
- Plasmonic and Surface Plasmon Research
- Natural product bioactivities and synthesis
- Quantum Dots Synthesis And Properties
- Graphene research and applications
- Semiconductor Quantum Structures and Devices
- Photonic and Optical Devices
- Transportation Planning and Optimization
- Cancer, Hypoxia, and Metabolism
- ZnO doping and properties
Sun Yat-sen University
2016-2025
Fujian Medical University
2016-2025
Shanghai Jiao Tong University
2016-2025
Southeast University
2015-2025
Tsinghua University
2016-2025
Beijing Tongren Hospital
2016-2025
National University of Singapore
2010-2025
Jiangsu University of Science and Technology
2005-2025
Southern Medical University
2016-2025
Huazhong University of Science and Technology
2016-2025
<h3>Importance</h3> Coronavirus disease 2019 (COVID-19) is an emerging infectious that was first reported in Wuhan, China, and has subsequently spread worldwide. Risk factors for the clinical outcomes of COVID-19 pneumonia have not yet been well delineated. <h3>Objective</h3> To describe characteristics patients with who developed acute respiratory distress syndrome (ARDS) or died. <h3>Design, Setting, Participants</h3> Retrospective cohort study 201 confirmed admitted to Wuhan Jinyintan...
The dimensionless thermoelectric figure of merit (ZT) in bismuth antimony telluride (BiSbTe) bulk alloys has remained around 1 for more than 50 years. We show that a peak ZT 1.4 at 100 degrees C can be achieved p-type nanocrystalline BiSbTe alloy. These materials were made by hot pressing nanopowders ball-milled from crystalline ingots under inert conditions. Electrical transport measurements, coupled with microstructure studies and modeling, the improvement is result low thermal...
Significance Carbon has many faces––from diamond and graphite to graphene, nanotube, fullerenes. Whereas hexagons are the primary building blocks of these materials, except for C 20 fullerene, carbon structures made exclusively pentagons not known. Because exotic properties associated with their unique structures, some fundamental questions arise: Is it possible have materials if so will they be stable unusual properties? Based on extensive analyses simulations we show that penta-graphene,...
Abstract Chemically functionalized single-walled carbon nanotubes (SWNT) have shown promise in tumor-targeted accumulation mice and exhibit biocompatibility, excretion, little toxicity. Here, we show vivo SWNT drug delivery for tumor suppression mice. We conjugate paclitaxel (PTX), a widely used cancer chemotherapy drug, to branched polyethylene glycol chains on SWNTs via cleavable ester bond obtain water-soluble SWNT-PTX conjugate. affords higher efficacy suppressing growth than clinical...
Abstract Chemodynamic therapy (CDT) utilizes iron‐initiated Fenton chemistry to destroy tumor cells by converting endogenous H 2 O into the highly toxic hydroxyl radical ( . OH). There is a paucity of Fenton‐like metal‐based CDT agents. Intracellular glutathione (GSH) with OH scavenging ability greatly reduces efficacy. A self‐reinforcing nanoagent based on MnO reported that has both Mn 2+ delivery and GSH depletion properties. In presence HCO 3 − , which abundant in physiological medium,...
Carbon-based nanomaterials have been widely used as catalysts or catalyst supports in the chemical industry for energy environmental applications due to their fascinating properties. High surface areas, tunable porosity, and functionalization are considered be crucial enhance catalytic performance of carbon-based materials. Recently, newly emerging metal–organic frameworks (MOFs) built from metal ions polyfunctional organic ligands proved promising self-sacrificing templates precursors...
Abstract Katalyse mit Methode : Eine ganze Reihe katalytischer Palladiumsysteme für die C‐H‐Aktivierung/C‐C‐Kupplung (siehe Schema) wurde in jüngerer Zeit entwickelt. Ein besonderer Schwerpunkt ist Pd II ‐katalysierte Kupplung von C‐H‐Bindungen metallorganischen Reagentien durch /Pd 0 ‐Katalysezyklen. Die Vielseitigkeit dieser Katalysemethode wird demonstriert, zudem werden offene Fragen sowie das Entwicklungspotenzial des Gebietes angesprochen. magnified image In den letzten zehn Jahren...
Carbon nanotubes are promising new materials for molecular delivery in biological systems. The long-term fate of intravenously injected into animals vivo is currently unknown, an issue critical to potential clinical applications these materials. Here, using the intrinsic Raman spectroscopic signatures single-walled carbon (SWNTs), we measured blood circulation SWNTs and detect various organs tissues mice ex over a period three months. Functionalization by branched polyethylene-glycol (PEG)...
We constructed highly oriented and ordered macropores within metal-organic framework (MOF) single crystals, opening up the area of three-dimensional-ordered macro-microporous materials (that is, containing both macro- micropores) in single-crystalline form. Our methodology relies on strong shaping effects a polystyrene nanosphere monolith template double-solvent-induced heterogeneous nucleation approach. This process synergistically enabled situ growth MOFs voids, rendering crystal with...
Abstract The recently proposed digital coding metasurfaces make it possible to control electromagnetic (EM) waves in real time, and allow the implementation of many different functionalities a programmable way. However, current configurations are only space-encoded, do not exploit temporal dimension. Here, we propose general theory space-time modulated obtain simultaneous manipulations EM both space frequency domains, i.e., propagation direction harmonic power distribution simultaneously. As...
Chemodynamic therapy (CDT) employs Fenton catalysts to kill cancer cells by converting intracellular H2O2 into hydroxyl radical (•OH), but endogenous is insufficient achieve satisfactory anticancer efficacy. Despite tremendous efforts, engineering CDT agents with specific and efficient self-supplying ability remains a great challenge. Here, we report the fabrication of copper peroxide (CP) nanodot, which first example Fenton-type metal nanomaterial, its use as an activatable agent for...
We report the in vivo targeting and imaging of tumor vasculature using arginine-glycine-aspartic acid (RGD) peptide-labeled quantum dots (QDs). Athymic nude mice bearing subcutaneous U87MG human glioblastoma tumors were administered QD705-RGD intravenously. The fluorescence intensity reached maximum at 6 h postinjection with good contrast. results reported here open up new perspectives for integrin-targeted near-infrared optical may aid cancer detection management including imaging-guided surgery.
Two 3d-4f heterometallic coordination polymers {[Ln(PDA)3Mn1.5(H2O)3].3.25H2O}infinity with 1D channels were synthesized under hydrothermal conditions (PDA = pyridine-2,6-dicarboxylic acid; Ln Eu (1); Tb (2)). The emission intensities of 1 and 2 increased significantly upon addition Zn2+, while the introduction other metal ions caused intensity to be either unchanged or weakened. case implies that may used as luminescent probes Zn2+.
Single layer of graphite (graphene) was predicted and later experimentally confirmed to undergo metal-semiconductor transition when fully hydrogenated (graphane). Using density functional theory we show that half the hydrogen in this graphane sheet is removed, resulting semihydrogenated graphene (which refer as graphone) becomes a ferromagnetic semiconductor with small indirect gap. Half-hydrogenation breaks delocalized pi bonding network graphene, leaving electrons unhydrogenated carbon...