- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Vascular Malformations Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Neurosurgical Procedures and Complications
- Long-Term Effects of COVID-19
- Coenzyme Q10 studies and effects
- Organ Transplantation Techniques and Outcomes
- Peripheral Artery Disease Management
- Liver Disease and Transplantation
- Cardiac tumors and thrombi
- Organ Donation and Transplantation
- Cardiac Structural Anomalies and Repair
- Dementia and Cognitive Impairment Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced MRI Techniques and Applications
- Intracerebral and Subarachnoid Hemorrhage Research
- COVID-19 and healthcare impacts
- Functional Brain Connectivity Studies
- Cerebrospinal fluid and hydrocephalus
- Cardiovascular Effects of Exercise
- Advanced battery technologies research
Hospital Universitario Virgen de la Arrixaca
2013-2025
Eppendorf (Germany)
2025
Hospital General Universitario de Albacete
2015
Complejo Hospitalario Universitario de Albacete
2015
University of Bern
2013
Society of Interventional Radiology
2012
Hospital Universitario 12 De Octubre
2000
Background and Purpose— Mechanical thrombectomy using stent retriever devices have been advocated to increase revascularization in intracranial vessel occlusion. We present the results of a large prospective study on use Solitaire Flow Restoration patients with acute ischemic stroke. Methods— Thrombectomy for Acute Revascularization was an international, multicenter, prospective, single-arm anterior circulation strokes treated within 8 hours symptom onset. Strict criteria site selection were...
BackgroundEndovascular treatment (EVT) of stroke with large-vessel occlusion is known to be safe and effective. The effect EVT for medium or distal vessels unclear.MethodsWe randomly assigned participants an isolated (occlusion the nondominant codominant M2 segment middle cerebral artery [MCA]; M3 M4 MCA; A1, A2, A3 anterior artery; P1, P2, P3 posterior artery) receive plus best medical alone within 24 hours after participant was last seen well. primary outcome level disability at 90 days,...
For patients with symptomatic acute occlusions of the internal carotid artery below circle Willis, endovascular and best medical treatment were both effective safe therapeutic options.
<h3>BACKGROUND AND PURPOSE:</h3> The aim of this study was to report the CT evolution and clinical significance HCA after intra-arterial mechanical thrombectomy (revascularization by using retrievers and/or other devices without concomitant delivery thrombolytics) in our patients. These lesions are common thrombolysis, being considered a negative prognostic sign. Their pure remains unknown. <h3>MATERIALS METHODS:</h3> Forty-eight patients were treated with retrievable stents between April...
To estimate the prevalence of amnestic mild cognitive impairment (aMCI), impairment, no dementia (CIND) and in a general elderly population to examine associated socio-demographic factors.The Ariadna study is population-based cross-sectional function involving 1074 individuals aged 65-96 years from Murcia Region southeastern Spain. Prevalence, adjusted odds ratio (OR) 95% confidence intervals (CI) were calculated.The overall was 8.7% (95% CI 7.1-10.5) for aMCI, 14.5% 12.4-16.8) CIND 5.5%...
Acute vertebrobasilar occlusion is an ominous disease with few proved effective treatments. Experience stent retrievers scarce and limited to combined therapies (stent associated previous intravenous fibrinolysis, intra-arterial thrombolysis, or other mechanical devices). We present our experience 18 patients treated direct thrombectomy by using retrievers.Eighteen were at hospital. The mean age was 67.5 years. Clinical presentation sudden deterioration in consciousness level 61.2%...
Futile recanalization after acute ischemic stroke occurs in almost half of the patients despite optimal angiographic results. Multimodal neuroimaging may help to improve patient's selection but is still dismissed by many interventionalists. Our aim was evaluate accuracy each parameter multimodal computed tomography (CT) and their combination for predicting futile successful thrombectomy.We retrospectively reviewed a cohort consecutive with anterior circulation stroke, fully assessable CT,...
The purpose of the COMPLETE (International Acute Ischemic Stroke Registry With Penumbra System Aspiration Including 3D Revascularization Device) registry was to evaluate generalizability safety and efficacy (Penumbra, Inc, Alameda) in a real-world setting.COMPLETE global, prospective, postmarket, multicenter registry. Patients with large vessel occlusion-acute ischemic stroke who underwent mechanical thrombectomy using or without Device as frontline approach were enrolled at 42 centers (29...
Tandem stroke caused by a cervical carotid loop acute dissection with distal embolism is generally challenging procedure for the neurointerventionalist. The section of dissected artery difficults quick access to occlusion and it also complicated lesion treat itself, due complex navigation re-thrombosis that precludes in situ angioplasty and/or definite stenting. 1 – 6 We present patient an tandem Middle Cerebral Artery (MCA) Internal Carotid (ICA) underlying dissection. After several failed...
Background Although mechanical thrombectomy (MT) is an effective treatment for large vessel occlusion (LVO) with a high successful recanalization rate, MT failure (MTF) occurs in 10–15% of cases and associated unfavorable outcomes. However, little known about the clinical, technical, radiological reasons MTF. We investigated technical factors Methods conducted retrospective analysis consecutive patients anterior LVO prospectively included ongoing observational multicenter ROSSETTI registry....
<i>Background/Aims:</i> To evaluate <sup>1</sup>H-labelled magnetic resonance spectroscopy (MRS) in patients with a low Mini Mental State Examination (MMSE) score identified during dementia community-based survey. <i>Methods:</i> A population sample of 1,500 individuals (>64 years old) was randomly selected. Two hundred and fifteen (MMSE ≤24) were sorted into clinical groups: dementia, Alzheimer’s disease, mild cognitive impairment (MCI), normal. Up to...
Strokes due to carotid artery occlusion (CAO) are associated with bad clinical prognosis and poor response intravenous thrombolysis. Several studies in the past have shown benefits of mechanical thrombectomy (MT) compared bridging therapy (BT) primary MT (PMT) large vessel occlusions, but only a few focused on specific population CAO their endovascular treatment.Retrospective review patients treated at our center between January 2010 June 2017 that (1) presented acute ischemic stroke caused...
To elucidate whether serum coenzyme Q10 levels are related with the risk for multiple sclerosis (MS) or a marker activity of disease, we compared and Q10/cholesterol ratio, in 31 patients MS (during exacerbations) 19 matched controls using high performance liquid chromatography technique. The mean ratio did not differ significantly between 2 study groups. values correlate age, age at onset, duration disease. These results suggest that concentrations unrelated useful
This study was supported by a Spanish grant from the Instituto de Salud Carlos III (ISCIII-FIS IP14/00971,2014-2017). The ITRIBIS project (Improving Translational Research Potential at Institute of Biomedicine Seville) has registration number REGPOT-2013-1. Cooperative Cerebrovascular Disease Network (INVICTUS+)(RD16/0019/0015). Fernando Mancha is Rio Hortega contract. Francisco Moniche PI PI15/01197 and PI18/01414 grants. This partially funded Abbott (Chicago, IL, USA) Grifols (Barcelona,...