Santiago Rosati

ORCID: 0000-0002-5613-1291
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Intracranial Aneurysms: Treatment and Complications
  • Vascular Malformations Diagnosis and Treatment
  • Stroke Rehabilitation and Recovery
  • Venous Thromboembolism Diagnosis and Management
  • Moyamoya disease diagnosis and treatment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neurosurgical Procedures and Complications
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Retinal and Optic Conditions
  • Cardiovascular Issues in Pregnancy
  • Infective Endocarditis Diagnosis and Management
  • Ocular Diseases and Behçet’s Syndrome
  • Meningioma and schwannoma management
  • Cerebral Venous Sinus Thrombosis
  • Traumatic Ocular and Foreign Body Injuries
  • Pituitary Gland Disorders and Treatments
  • Business, Innovation, and Economy
  • Healthcare Systems and Practices
  • Cardiac Health and Mental Health
  • Coronary Artery Anomalies
  • Neurological Disorders and Treatments
  • Cardiovascular Syncope and Autonomic Disorders
  • Vascular Malformations and Hemangiomas

Hospital Clínico San Carlos
2015-2025

Hospital General Universitario de Alicante Doctor Balmis
2024

Ramathibodi Hospital
2024

Mahidol University
2024

Comunidad de Madrid
2022-2024

Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2016-2019

Federico Santa María Technical University
2019

Mechanical thrombectomy techniques for intracranial medium vessel occlusions (MeVOs) have evolved in recent years, although the optimal approach is still unclear. The aim of this study was to investigate effectiveness and safety mechanical MeVOs using mini (0.017 inches microcatheter compatible) stent retrievers combined with low-profile (0.035 distal inner diameter) aspiration catheters through blind exchange/mini-pinning (BEMP) technique compared alone.Retrospective review a prospectively...

10.1161/strokeaha.120.030815 article EN Stroke 2020-10-19

Background First-pass effect (FPE) has been established as a key metric for technical success and strongly correlates with better clinical outcomes. Most data supporting improved outcomes the use of balloon guide catheter (BGC) predate advent last-generation large-bore intracranial aspiration catheters. We aim to evaluate impact BGC in FPE large cohort patients treated contemporary technology. Methods Patients were recruited from prospectively ongoing ROSSETTI registry. This registry...

10.1136/neurintsurg-2020-017027 article EN Journal of NeuroInterventional Surgery 2021-02-25

Background and purpose The first-pass effect (FPE), defined as a Expanded Treatment in Cerebral Ischaemia (eTICI) 2c/3 reperfusion, has emerged key metric of efficacy mechanical thrombectomy (MT) for acute ischaemic stroke. proximal balloon occlusion together with direct thrombus aspiration during stent retriever (PROTECT)-PLUS technique consists the use guide catheter combined MT approach involving contact retriever. aim this study is to assess effectiveness safety PROTECT-PLUS using distal...

10.1136/svn-2020-000833 article EN cc-by-nc Stroke and Vascular Neurology 2021-03-29

To demonstrate, by a cost-effectiveness analysis, the efficiency of mechanical thrombectomy (MT) versus medical management (MM) in patients with low Alberta Stroke Program Early CT Score (ASPECTS) from RESCUE Study.A model was designed to project both direct costs and quality-adjusted life-years (QALYs) MT MM eight European countries (Spain, UK, France, Italy, Belgium, Germany, Sweden, Netherlands). Our created based on previously published health-economic data those countries. Procedure...

10.1136/jnis-2022-019849 article EN cc-by-nc Journal of NeuroInterventional Surgery 2022-12-23

ABSTRACT Background and Purpose The safety effectiveness of endovascular techniques in elderly patients with large vessel occlusion (LVO) remain controversial. We investigated the angiographic clinical outcomes nonagenarians treated different using a balloon guide catheter (BGC), distal aspiration (DAC), and/or stent retriever (SR). Methods analyzed data from Registry Combined versus Single Thrombectomy Techniques (ROSSETTI) consecutive nonagenarian anterior circulation LVO compared those...

10.1111/jon.70012 article EN cc-by-nc Journal of Neuroimaging 2025-01-01

Background Although mechanical thrombectomy (MT) is an effective treatment for large vessel occlusion (LVO) with a high successful recanalization rate, MT failure (MTF) occurs in 10–15% of cases and associated unfavorable outcomes. However, little known about the clinical, technical, radiological reasons MTF. We investigated technical factors Methods conducted retrospective analysis consecutive patients anterior LVO prospectively included ongoing observational multicenter ROSSETTI registry....

10.1136/jnis-2025-023078 article EN Journal of NeuroInterventional Surgery 2025-04-25

Background: Chronic subdural hematoma (CSDH) is a common condition in older adults with rising rates of incidence. While burr hole drainage remains the standard treatment, it associated significant recurrence and complications. This study assesses MMA embolization Squid, both as standalone procedure an adjunct to surgery. Methods: Our prospective registry included 101 patients 134 CSDH cases treated at two tertiary care centers from December 2020 January 2024. Patients were divided into...

10.3390/diagnostics15111424 article EN cc-by Diagnostics 2025-06-03

<h3>BACKGROUND AND PURPOSE:</h3> Eye lenses are among the most sensitive organs to x-ray radiation and may be considered at risk during neurointerventional radiology procedures. The threshold dose produce eye lens opacities has been recently reduced 500 mGy by International Commission on Radiologic Protection. In this article, authors investigated doses delivered patients9 eyes interventional neuroradiology procedures a university hospital. <h3>MATERIALS METHODS:</h3> Small optically...

10.3174/ajnr.a4549 article EN cc-by American Journal of Neuroradiology 2015-11-05

Background First-pass recanalization via mechanical thrombectomy (MT) has been associated with improved clinical outcome in patients acute ischaemic stroke. The optimal approach to achieve first-pass effect (FPE) remains unclear. No study evaluated angiographic features the achievement of FPE. We aimed determine procedural approaches and signs that may predict Methods performed a prospective, multi-centre, observational FPE anterior circulation stroke treated MT between February June 2017....

10.1177/1591019919847623 article EN Interventional Neuroradiology 2019-05-09

Background and purpose Preoperative embolization of carotid paragangliomas is a common procedure in interventional neuroradiology. Direct puncture has shown less morbidity mortality than endovascular higher percentage devascularization. We describe our experience using Squid® as the only embolic agent direct glomus embolization. Methods retrospectively reviewed pre-embolization imaging tests, emphasizing volume lesion, clinical history data, technical aspects procedure, well approximate...

10.1177/1971400920910409 article EN The Neuroradiology Journal 2020-03-12

The Stent retriever Assisted Vacuum-locked Extraction (SAVE) technique in mechanical thrombectomy consists of the simultaneous use a stent and distal aspiration catheter, with removal both as unit when performing pass. This is safe procedure that provides high rate first-pass reperfusion.1 In M1 segment middle cerebral artery (MCA) occlusions, portion clot extending to upper lower MCA branches, can be challenging since thrombus not fully trapped, risk migration branch which placed. these...

10.1136/neurintsurg-2020-016061 article EN cc-by-nc Journal of NeuroInterventional Surgery 2020-06-25

10.1007/s00062-023-01264-4 article EN Clinical Neuroradiology 2023-03-01

Current consensus recommends extended vascular investigation in patients with spontaneous coronary artery dissection (SCAD). We here report our experience the use of magnetic resonance angiography (MRA) for screening extra-coronary arteriopathy presenting SCAD.Patients SCAD a Spanish centre underwent prospective contrast-enhanced MRA to assess cephalic and abdominopelvic arterial territories. Fibromuscular dysplasia (FMD) was diagnosed following European criteria. Other abnormalities were...

10.21037/cdt.2019.04.09 article EN Cardiovascular Diagnosis and Therapy 2019-06-01

Goyal et al described occlusions in M2/3, A2/3 and P2/3 as medium vessel (MeVOs); the only available controlled data of mechanical thrombectomy (MT) MeVOs is limited to middle cerebral artery M2 segment, suggesting that MT may be effective safe with high functional independence recanalization rates. The Stent retriever Assisted Vacuum-locked Extraction (SAVE) technique consists simultaneous use a stent distal aspiration catheter (DAC), removal both unit when performing pass; however, so far...

10.1136/neurintsurg-2020-016763 article EN cc-by-nc Journal of NeuroInterventional Surgery 2020-12-28

Background Cognitive improvement after endovascular embolization of an intracranial dural arteriovenous fistula (dAVF) remains unexplored. We aim to investigate cognitive changes following dAVFs. Methods Neuropsychology in ArterIal Fistula (NAIF) was a prospective multicentric study including patients with angiographic diagnosis dAVF who underwent over the course 4 years. A complete neuropsychological evaluation comprising five domains (attention and executive functions, memory, language,...

10.1136/jnis-2023-021033 article EN Journal of NeuroInterventional Surgery 2023-12-07

Background Mechanical thrombectomy (MT) is part of the standard care for stroke treatment, and improving its efficacy one main objectives clinical investigation. Of importance placement distal end balloon-guided catheters (BGC). We aim to determine if this influences outcomes. Methods analyzed data from ASSIST Registry, an international, multicenter prospective study 1492 patients. divided patients treated with BGC according BGC: low cervical (LCG (the lower 2/3 internal carotid artery...

10.1136/jnis-2024-021650 article EN cc-by-nc Journal of NeuroInterventional Surgery 2024-06-21

Background Efficient recanalization of occluded cerebral arteries is crucial in the treatment acute ischemic stroke. Double stent retrievers have shown potential to enhance rates on first pass. This study aims evaluate efficacy and safety double retriever technique predictors achieving first-pass effect patients with Methods prospective multicenter involved 209 from 16 comprehensive stroke centers Spain. Patients occlusions anterior circulation were treated using Aperio Hybrid retriever. The...

10.1136/jnis-2024-022297 article EN Journal of NeuroInterventional Surgery 2024-09-17

The optimal endovascular treatment (EVT) technique for middle cerebral artery (MCA) M2 segment occlusions remains unknown. We aim to analyze whether reperfusion rate, procedure times, procedure-related complications, and clinical outcome differed between patients with isolated who underwent stent-retriever (SR) alone versus combined SR contact aspiration (CA) as a front-line EVT.Patients EVT MCA-M2 occlusion were recruited from the prospectively ongoing ROSSETTI registry. Patients divided...

10.1136/neurintsurg-2021-017987 article EN Journal of NeuroInterventional Surgery 2021-11-08
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