A5035924173- Lipoproteins and Cardiovascular Health
- Peripheral Artery Disease Management
- Geochemistry and Geologic Mapping
- Acute Ischemic Stroke Management
- Health Systems, Economic Evaluations, Quality of Life
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Cerebrovascular and Carotid Artery Diseases
- Acute Myocardial Infarction Research
- Chronic Disease Management Strategies
- Geological and Geochemical Analysis
- Diagnosis and Treatment of Venous Diseases
- Stroke Rehabilitation and Recovery
- Soil Geostatistics and Mapping
- COVID-19 Clinical Research Studies
- Dementia and Cognitive Impairment Research
- Cardiovascular Health and Disease Prevention
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Atrial Fibrillation Management and Outcomes
- Pharmaceutical Economics and Policy
- Chronic Kidney Disease and Diabetes
- Hydrocarbon exploration and reservoir analysis
- Long-Term Effects of COVID-19
- Global Health Care Issues
- Vaccine Coverage and Hesitancy
Universitat de Girona
2015-2025
Institut Universitari d'Investigació en Atenció Primària Jordi Gol
2014-2023
Institut d'Investigació Biomèdica de Girona
2015-2021
Public Health Laboratory Ivo de Carneri
2020
Catalan Institute for Water Research
2016-2019
Institut Català de la Salut
2017-2018
Primary Health Care
2017
Clínica Girona
2015
Institut Català de Ciències del Clima
2015
Universitat Politècnica de Catalunya
1991-2009
To assess whether statin treatment is associated with a reduction in atherosclerotic cardiovascular disease (CVD) and mortality old very adults without diabetes.Retrospective cohort study.Database of the Catalan primary care system (SIDIAP), Spain, 2006-15.46 864 people aged 75 years or more clinically recognised CVD. Participants were stratified by presence type 2 diabetes mellitus as non-users new users.Incidences CVD all cause compared using Cox proportional hazards modelling, adjusted...
Evidence is lacking about the effectiveness of risk reduction interventions in patients with asymptomatic peripheral arterial disease. This study aimed to assess whether statin therapy was associated a major adverse cardiovascular events (MACE) and mortality this population. Data were obtained from 2006 through 2013 Catalan primary care system's clinical records database (SIDIAP). Patients age 35 85 years an ankle-brachial index ≤0.95 without clinically recognized disease (CVD) included....
Updated estimates of incidence and prevalence dementia are crucial to ensure adequate public health policy. However, most the epidemiological studies in population Spain were conducted before 2010. This study assessed validity diagnoses recorded electronic records contained a large primary-care database determine if they could be used for research purposes. Then, update epidemiology Catalonia (Spain), we estimated crude standardized rates 2016.The System Development Research Primary Care...
Objective To examine the association between chronic immune-mediated diseases (rheumatoid arthritis, systemic lupus erythematosus or following inflammatory diagnoses groups: bowel diseases, polyarthropathies, connective tissue disorders and spondylopathies) 6-year coronary artery disease, stroke, cardiovascular disease incidence overall mortality; to estimate population attributable fractions for all four end-points each disease. Methods Cohort study of individuals aged 35–85 years, with no...
Cold spells and heatwaves increase mortality. However little is known about the effect of or cold on cardiovascular morbidity. This study aims to assess diseases in a Mediterranean region (Catalonia, Southern Europe).We conducted population-based retrospective study. Data were obtained from System for Development Research Primary Care Catalan Meteorological Service. The outcome was first emergency hospitalizations due coronary heart disease, stroke, failure. Exposures were: spells; 3 7...
Familial hypercholesterolemia (FH), the most frequent hereditary cause of premature coronary heart disease (CHD), is underdiagnosed and insufficiently treated.The objectives study were to estimate prevalence FH phenotype (FH-P) describe its clinical characteristics in a Mediterranean population.Data obtained from Catalan primary care system's records database (Catalan acronym: SIDIAP). Patients aged >7 years with at least 1 low-density lipoprotein cholesterol measurement recorded between...
In the statin era, incidence of atherosclerotic cardiovascular diseases (ASCVD) in patients with familial hypercholesterolemia (FH) has not been updated. We aimed to determine ASCVD FH-phenotype (FH-P) and compare it that normal low-density lipoprotein cholesterol (LDL-C) patients. performed a retrospective cohort study using Database Catalan primary care system, including ≥18-year-old an LDL-C measurement. From 1,589,264 available before 2009, 12,823 fulfilled FH-P criteria 514,176 were...
Background Area-based measures of economic deprivation are seldom applied to large medical records databases establish population-scale associations between and disease. Objective To study the association incidence common cancer types in a Southern European region. Methods Retrospective ecological using SIDIAP (Information System for Development Research Primary Care) database longitudinal electronic representative population Catalonia (Spain) MEDEA index based on urban socioeconomic...
Electronic health records (EHR) from primary care are emerging in Alzheimer's disease (AD) research, but their accuracy is a concern. We aimed to validate AD diagnoses using additional information provided by general practitioners (GPs), and register of dementias.This retrospective observational study obtained data the System for Development Research Primary Care (SIDIAP). Three algorithms combined International Statistical Classification Diseases (ICD-10) Anatomical Therapeutic Chemical...
Abstract Familial hypercholesterolemia (FH) is an autosomal dominant disease that has a prevalence of approximately 1/250 inhabitants and the most frequent cause early coronary heart (CHD). We included 1.343.973 women 1.210.671 men with at least one LDL-c measurement from Catalan primary care database. identified 14.699 subjects hypercholesterolemia-Phenotype (FH-P) based on cut-off points by age (7.033 919 women, 5.088 1659 in secondary prevention, respectively). Lipid lower therapy (LLT),...
Abstract Background Our aims were to describe respiratory sequelae up 12 months after discharge in COVID-19 patients with severe pneumonia requiring non-invasive support therapies. Methods This study was undertaken at University Hospital Doctor Josep Trueta (Girona, Spain) between March 2020 and June 2020. Three discharge, we evaluated their dyspnoea performed Saint George’s questionnaire, pulmonary function tests, blood test, 6-min walking a high-resolution CT (HRCT). At the six 12-month...
•Three statin patterns were defined, based on type, potency, and 1-year change.•Patterns of use defined as low, moderate, high intensity.•Prescription was not related to baselineLDL-cholesterol levels.•Management in primary care should be focused improving adherence treatment.•Initial pattern prescribed LDL-cholesterol or CV risk needs bettter alignment. ObjectiveTo describe real-life cholesterol goal attainment a retrospective cohort patients with cardiovascular risk.MethodsRetrospective...
Objective We sought to compare the association of categorized ankle–brachial index (ABI) with mortality and complications diabetes in persons no symptoms peripheral arterial disease (PAD) primary cardiovascular prevention. Research design methods This is a retrospective cohort study type 2 aged 35–85 years, from 2006 2011. Data were obtained Sistema d'Informació per al Desenvolupament de la Investigació en Atenció Primària (SIDIAP Q ). Participants had an ABI measurement that was classified...
The impact of extreme diurnal temperature range (DTR) on cardiovascular morbidity in Mediterranean regions remains uncertain. We aimed to analyse the low DTR (stable temperature) or high (changeable hospitalisations Catalonia (Southern Europe).We conducted a self-controlled case series study using whole-year data from System for Development Research Primary Care database and 153 weather stations Catalan Meteorological Service. outcome was first emergency hospitalisation. Monthly percentiles...
Abstract Objective To develop a domain-specific large language model (LLM) for LI-RADS v2018 categorization of hepatic observations based on free-text descriptions extracted from MRI reports. Material and methods This retrospective study included 291 small liver observations, divided into training ( n = 141), validation 30), test 120) datasets. Of these, 120 were fictitious, 171 175 reports single institution. The algorithm’s performance was compared to two independent radiologists one...
ABSTRACT Background and Purpose Endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) with M2 segment occlusion of the middle cerebral artery (MCA) is debatable. This study assessed efficacy, safety, functional outcomes EVT in patients, examining differences based on dominance occluded (DomM2 vs. Non‐DomM2). Methods A prospective cohort 108 patients AIS resulting from MCA who underwent was analyzed. We compared demographic, clinical, angiographic, clinical outcome data (National...
ABSTRACT Background and Purpose The safety effectiveness of endovascular techniques in elderly patients with large vessel occlusion (LVO) remain controversial. We investigated the angiographic clinical outcomes nonagenarians treated different using a balloon guide catheter (BGC), distal aspiration (DAC), and/or stent retriever (SR). Methods analyzed data from Registry Combined versus Single Thrombectomy Techniques (ROSSETTI) consecutive nonagenarian anterior circulation LVO compared those...
<title>Abstract</title> Background We aimed to describe respiratory sequelae up 4 years after discharge in COVID-19 patients with severe pneumonia having required non-invasive support therapies. Methods This study was conducted between March 2020 and June at University Hospital Doctor Josep Trueta (Girona, Spain). assessed the patient’s dyspnoea performed, pulmonary function tests, a high-resolution CT (HRCT), 6-minute walking test, blood Saint George’s questionnaire 3 months discharge. At...
Background Although mechanical thrombectomy (MT) is an effective treatment for large vessel occlusion (LVO) with a high successful recanalization rate, MT failure (MTF) occurs in 10–15% of cases and associated unfavorable outcomes. However, little known about the clinical, technical, radiological reasons MTF. We investigated technical factors Methods conducted retrospective analysis consecutive patients anterior LVO prospectively included ongoing observational multicenter ROSSETTI registry....
Background Medium vessel occlusion (MVO) mechanical thrombectomy (MT) has shown promising outcomes and safety profiles, comparable to those of large thrombectomy. Objective To assess the efficacy CatchView Mini (CVM) stent retriever (Balt, Montmorency, France) in patients with acute stroke proximal distal MVO (pMVO vs dMVO), respectively. Methods We analyzed retrospective data consecutive who underwent MT CVM retriever. categorized occlusions into pMVO group (segments A1, M2, P1) versus dMVO...
ABSTRACT Background and Purpose The superiority of achieving modified Treatment in Cerebral Ischemia (mTICI) from multiple passes versus mTICI 2b a single pass remains uncertain. We aimed to assess whether additional M1 occlusion patients with first‐pass score improved clinical functional outcomes. Methods analyzed Registry Combined vs. Single Thrombectomy Techniques registry data consecutive M1‐occlusion patients, comparing outcomes those 2b‐stopped after the first continued mechanical...
Bone marrow mononuclear cell (BM-MNC) intraarterial transplantation has emerged as a potential stroke therapy. We aimed to determine whether BM-MNC therapy induces changes in diffusion tensor imaging metrics of major white matter tracts. The IBIS trial was an investigator-initiated multicenter, phase IIb, randomized, controlled, assessor-blinded, clinical trial. Seventy-seven patients (aged 18-80 years) with nonlacunar middle cerebral artery ischemic within 1 7 days from onset and National...
ABSTRACT Background and Purpose Large‐bore aspiration catheters (LBACs) are used for thrombectomy in large vessel occlusion (LVO), either as a standalone direct first‐pass technique or combined with stent retriever (ASR). LBAC design may influence ASR efficacy. We compared the safety performance of novel MIVI Q segmental catheter well‐established SOFIA device thrombectomy. Methods analyzed data from Registry cOmbined vS SinglE Thrombectomy TechnIques registry consecutive patients anterior...