A5022229461- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Dementia and Cognitive Impairment Research
- Atrial Fibrillation Management and Outcomes
- Autoimmune and Inflammatory Disorders
- IgG4-Related and Inflammatory Diseases
- Cerebral Venous Sinus Thrombosis
- Antiplatelet Therapy and Cardiovascular Diseases
- Optical Imaging and Spectroscopy Techniques
- Advanced Neuroimaging Techniques and Applications
- Educational and Psychological Assessments
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Sarcoidosis and Beryllium Toxicity Research
Hospital Universitario Virgen del Rocío
2017-2025
Universidad de Sevilla
2022-2025
Instituto de Biomedicina de Sevilla
2022-2024
Introduction: Prior clinical trials of oral anticoagulant (OAC) reversal have demonstrated improved outcomes in patients with OAC-related intracerebral hemorrhage (ICH). However, despite guidelines recommend avoiding the withdrawal medical support within first 2 days, about a quarter ICH do not receive an OAC agent. We aimed to determine factors predictive administration agent these patients. Methods: Prespecified analysis from Anticoagulant-Related (ARICH) registry, multicenter,...
Bone marrow mononuclear cell (BM-MNC) intraarterial transplantation has emerged as a potential stroke therapy. We aimed to determine whether BM-MNC therapy induces changes in diffusion tensor imaging metrics of major white matter tracts. The IBIS trial was an investigator-initiated multicenter, phase IIb, randomized, controlled, assessor-blinded, clinical trial. Seventy-seven patients (aged 18-80 years) with nonlacunar middle cerebral artery ischemic within 1 7 days from onset and National...
Several antithrombotic treatments during emergent carotid artery stenting (eCAS) have been proposed, but an appropriate protocol to balance risk-benefit is not well known.
Background: TMA-93 examines binding by images, a potential advantage for less-educated individuals. Objective: To obtain norms from older Spanish adults TMA-93. Methods: A cross-sectional normative study was undertaken in general neurology outpatient clinic of university hospital the Southern region Andalusia. Partners patients who attended were systematically recruited when eligible: aged 50 and over, no memory complaints, total score equal or above percentile 10 on Phototest. Age, gender,...
<h3>BACKGROUND AND PURPOSE:</h3> Antithrombotic therapy following carotid artery stent placement with concomitant atrial fibrillation is not well-established. Our aim was to assess the safety and efficacy of combination direct oral anticoagulants a P2Y12 inhibitor at 30 days after in patients fibrillation. <h3>MATERIALS METHODS:</h3> We designed an observational single-center study including who underwent studied 3 groups according antithrombotic therapy: 1) plus clopidogrel (DC) group:...
Abstract Rationale In-stent reocclusion after endovascular therapy has a negative impact on outcomes in acute ischemic stroke (AIS) due to tandem lesions (TL). Optimal antiplatelet approach these patients avoid in-stent is yet be elucidated. Aims To assess efficacy and safety of intravenous tirofiban versus aspirin undergoing MT plus carotid stenting the setting AIS TL. Sample size estimates Two hundred forty will enrolled, 120 every treatment arm. Methods design A multicenter, prospective,...
Carotid reocclusion (CRO) after mechanical thrombectomy (MT) in acute ischemic stroke (AIS) due to tandem lesion (TL) or isolated internal carotid occlusion (ICO) is associated with worse clinical outcomes. Our aim was analyze the predictors and impact of CRO.A retrospective single-center analysis all patients anterior circulation strokes who underwent MT prospectively included a registry between 2017 2020 performed. ICO TL as causes were included. Stent deployment left discretion...
In-stent thrombosis after mechanical thrombectomy (MT) worsen outcomes in acute ischemic stroke (AIS) due to tandem lesions (TL). Although an optimal antiplatelet therapy is needed, the best approach avoid in-stent yet be elucidated.
ABSTRACT BACKGROUND The evolution of ischemic stroke is different according to sex and one the main causes death in women. In literature, it not clear if this due biological differences or disparities medical care. Previous studies have shown that women are less likely receive acute treatment, center type an important predictor door-to-needle times. We investigated whether attended a similar way men telestroke network with specialized physicians. METHODS A prospective registry strokes...
Varón de 31 años con dolor abdominal paroxístico 2 meses evolución y cuadro diarreico. Las pruebas complementarias realizadas pusieron manifiesto la presencia múltiples adenopatías, esplenomegalia, lesiones focales hipodensas en hígado bazo, así como una masa intraasa íleon terminal. Finalmente se establece el diagnóstico sarcoidosis afectación principalmente digestiva. Existen pocos casos descritos literatura científica gastrointestinal. Para es necesario sospecha clínica alta, este dentro...