A5023856382- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Vascular Malformations Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Antiplatelet Therapy and Cardiovascular Diseases
- Neurological Disease Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurological Disorders and Treatments
- Peripheral Neuropathies and Disorders
- Vasculitis and related conditions
- Moyamoya disease diagnosis and treatment
- Neurosurgical Procedures and Complications
- Peripheral Artery Disease Management
- Aortic Disease and Treatment Approaches
- Mitochondrial Function and Pathology
- CNS Lymphoma Diagnosis and Treatment
- Meningioma and schwannoma management
- Neuroinflammation and Neurodegeneration Mechanisms
- Biochemical Acid Research Studies
- Fetal and Pediatric Neurological Disorders
- Brain Metastases and Treatment
- Multiple Sclerosis Research Studies
Paracelsus Medical University
2014-2023
Health and Education Research Management and Epidemiologic Services (United States)
2023
Neurology, Inc
2011-2023
University of Salzburg
2015-2021
Unfallkrankenhaus Salzburg
2021
The University of Melbourne
2018
Université Paris Cité
2018
Maastricht University
2018
University Medical Center
2018
University Hospital and Clinics
2018
Background and Purpose— Mechanical thrombectomy using stent retriever devices have been advocated to increase revascularization in intracranial vessel occlusion. We present the results of a large prospective study on use Solitaire Flow Restoration patients with acute ischemic stroke. Methods— Thrombectomy for Acute Revascularization was an international, multicenter, prospective, single-arm anterior circulation strokes treated within 8 hours symptom onset. Strict criteria site selection were...
In patients with large ischemic stroke, thrombectomy within 12 hours after onset was superior to best medical treatment in reducing 90-day functional disability irrespective of the collateral status on single-phase CT angiography images.
<h3>BACKGROUND AND PURPOSE:</h3> Revascularization of large cerebral artery occlusion is the therapeutic goal in stroke therapy. Currently, many recanalization devices are clinical use. This study compares outcome parameters, efficacy, and safety new generation stent-retriever with well-established Merci retriever. <h3>MATERIALS METHODS:</h3> All patients who received endovascular mechanical therapy were prospectively registered. One hundred twenty-two treated either stent retrievers,...
OBJECTIVE The authors compared the Contour Neurovascular System (Contour) with Woven EndoBridge (WEB) device for treatment of wide-necked cerebral aneurysms at a bifurcation or sidewall. METHODS Prospective clinical and radiological data were collected all patients treated either WEB tertiary university hospital from May 2018 to June 2022. RESULTS In who had least 3 months follow-up available (median patient age 60.0 [IQR 51.8–67.0] years, male/female ratio 1:1.4), 40 in 34 30 WEB. Overall,...
Introduction The direct aspiration first pass technique (ADAPT) has been introduced as a rapid and safe endovascular treatment strategy in patients with ischemic stroke. Objective To determine the technical feasibility, safety, functional outcome ADAPT using new large-bore 6F SOFIA Plus catheter. Methods A retrospective analysis of prospectively collected data from six university hospitals was performed. following parameters all acute stroke procedures (June 2015– January 2016) catheter were...
BACKGROUND: Recent randomized trials demonstrated the beneficial effect of endovascular therapy in patients with low Alberta Stroke Program Early Computed Tomography Score. Despite large follow-up infarct volumes, a significantly increased rate good functional outcomes was observed, challenging role volume as predictive imaging marker. This analysis evaluates extent to which effects thrombectomy on are explained by (1) and (2) early neurological status stroke METHODS: TENSION trial conducted...
A large proportion of patients with multiple sclerosis (MS) have spasticity, which has a marked impact on their quality life. Anecdotal evidence suggests beneficial effect cannabis spasticity as well pain. Recently, randomized, double-blind, placebo-controlled studies confirmed the clinical efficacy cannabinoids for treatment in MS. Based these data, nabiximols (Sativex), 1:1 mix Δ-9-tetrahydrocannabinol and cannabidiol extracted from cloned Cannabis sativa chemovars, received approval...
Despite various measures to protect against distal embolization during carotid artery stenting (CAS), periprocedural ischemic lesions are still encountered.To evaluate the cerebral diffusion weighted imaging (DWI) lesion burden after CASPER stent placement.Patients who underwent CAS using system were reviewed. Degrees of stenosis and plaque configuration determined. All patients pretreated with dual antiplatelet agents pre- postprocedural MRI was obtained. procedures performed by a single...
The Pipeline Embolization Device (PED; Medtronic) has been used off-label for the treatment of challenging posterior circulation aneurysms. Data on this modality are primarily limited to small retrospective single-center series.To assess safety and efficacy by establishing an international, multicenter collaboration.Consecutive aneurysms treated with PED from 2012 2019 across 11 neurovascular centers were retrospectively reviewed. Baseline demographics, aneurysm characteristics,...
Treatment of middle cerebral artery (MCA) aneurysms has been historically considered as the almost exclusive domain microsurgical clipping. This retrospective single-center study assesses whether clipping or endovascular treatment (i.e. coiling and/or stenting) for MCA yielded better occlusion rates and clinical outcome.We identified patients with a minimum follow-up 12 months who had undergone aneurysm repair either by between 2005 2015. Aneurysm were assessed Raymond-Roy Occlusion...
Purpose To report the results of a retrospective analysis prospectively collected data evaluating safety and efficacy double layer stent engineered for carotid artery occlusive disease. Methods Between January 2014 February 2017, 138 patients (25.4% women; median age 71 years) underwent Casper implantation stenosis. Eligibility criteria included stenosis >70% vessel diameter (or >50% with ulceration) in symptomatic or asymptomatic >80% at bifurcation proximal internal artery. For...
Data on neuropsychological outcome after carotid artery stenting (CAS) remain inconsistent, furthermore cognitive seems to be unpredictable in the individual case. Previous studies reporting improvement or decline might due ceiling and floor effects of applied tests. We testing before CAS, avoiding pitfall effects.In our prospective database, we identified 72 patients free clinical stroke with ≥70% stenosis, who were treated CAS. They administered a neurocognitive test battery 3 months CAS...
To evaluate the occurrence and risk factors of acute in-stent thrombosis or stent occlusion in patients with tandem occlusions receiving intracranial mechanical thrombectomy emergent extracranial internal carotid artery stenting a dual layer stent.Multicenter retrospective data collection analysis stroke databases seven comprehensive centers from three European countries.Overall, 160 (mean (SD) age 66 (12) years; 104 men (65%); median (IQR) baseline NIHSS 14 (9-18); IV lysis, n=97 (60.6%))...
Flow diversion is a common endovascular treatment for cerebral aneurysms, but studies comparing different types of flow diverters are scarce.To perform propensity score matched cohort study the Pipeline Embolization Device (PED) and Redirection Intraluminal (FRED) posterior circulation aneurysms.Consecutive aneurysms treated at 25 neurovascular centers with either PED or FRED were collected. Propensity matching was used to control age, duration follow-up imaging, adjunctive coiling, aneurysm...
Introduction: Basilar artery occlusion (BAO) causes mortality up to 90%. Methods: A total of 99 patients with BAO received either endovascular (endovascular mechanical recanalization and/or intra-arterial optional intravenous thrombolysis [IVT] as bridging concept) or conservative medical treatment (IVT oral therapy). Outcome parameters were measured in accordance the cerebral infarction (TICI), National Institutes Health Stroke Scale (NIHSS), and modified Rankin (mRS) scores. Results: In...
Endovascular treatment of intracranial vascular diseases, such as aneurysms, is often challenged by unfavorable anatomy. The Bendit Steerable Microcatheter (Bendit Technologies, Tel Aviv, Israel) has bending and torqueing capabilities designed to improve navigation stability during device delivery, with or without a guidewire. We describe our preclinical experience the 17 21 microcatheters in rabbit aneurysm model.Bifurcation side wall aneurysms were created surgically six New Zealand...
<h3>BACKGROUND AND PURPOSE:</h3> Flow diversion for the posterior circulation remains a promising treatment option selected aneurysms. The Flow-Redirection Intraluminal Device (FRED) system has not been previously assessed in large cohort of patients with purpose present study was to assess safety and efficacy FRED this location. <h3>MATERIALS METHODS:</h3> Consecutive aneurysms treated at 8 centers participating European (EuFRED) between April 2012 January 2019 were retrospectively...
Retreatment options after the use of newly launched Woven EndoBridge cerebral aneurysm embolization device (WEB II) are mostly unknown. Nine months WEB II implantation, a 55-year-old female patient presented with regrowth an MCA aneurysm. For first time, standard balloon-assisted coiling was used to close regrown proximal implant. We report on feasibility and safety implantation device.