A5038929202- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Meningioma and schwannoma management
- Cardiac, Anesthesia and Surgical Outcomes
- Central Venous Catheters and Hemodialysis
- Cerebrospinal fluid and hydrocephalus
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and genetic disorders
- Aortic Disease and Treatment Approaches
- Case Reports on Hematomas
- Glaucoma and retinal disorders
- Vitamin K Research Studies
- Cardiovascular Health and Disease Prevention
- Advanced Glycation End Products research
Geisinger Health System
2018-2025
Geisinger Medical Center
2018-2024
Sheba Medical Center
2010-2021
Geisinger Neuroscience Institute
2018-2021
Paracelsus Medical University
2018-2020
Saarland University
2020
Swedish Medical Center
2018-2020
Palm Beach Neurology
2020
Commonwealth Medical College
2018-2019
University of California, San Diego
2019
Background Currently, there are no large-scale studies in the neurointerventional literature comparing safety between transradial (TRA) and transfemoral (TFA) approaches for flow diversion procedures. This study aims to assess complication rates a large multicenter registry TRA versus TFA diversion. Methods We retrospectively analyzed cases cerebral aneurysms from 14 institutions 2010 2019. Pooled analysis of proportions was calculated using weighted with 95% CI account results multiple...
Mechanical thrombectomy is the established treatment for acute ischemic stroke due to large vessel occlusion (LVO). The authors sought identify early predictors of a favorable outcome in patients treated with mechanical thrombectomy.
Background and Purpose— Accurate prediction of acute ischemic stroke (AIS) caused by anterior large vessel occlusion (LVO) that is amendable to mechanical thrombectomy remains a challenge. We developed validated model for circulation LVO using past medical history elements present on admission neurological examination. Methods— retrospectively reviewed AIS patients admitted between 2009 2017 3 hospitals within healthcare system in the United States. Patients with occlusions internal carotid...
Tenecteplase (TNK) is a genetically modified variant of alteplase (TPA) and has been established as non-inferior alternative to TPA in acute ischemic stroke (AIS). Whether TNK exerts distinct benefits large vessel occlusion (LVO) AIS still being investigated.To describe our first-year experience after healthcare system-wide transition from the primary thrombolytic.Patients with who received intravenous thrombolytics between January 2020 August 2022 were retrospectively reviewed. All patients...
BACKGROUND Venous sinus stenting (VSS) is increasingly performed for managing venous stenosis associated with refractory idiopathic intracranial hypertension and/or pulsatile tinnitus. The Monopoint System (MS; Route 92 Medical, San Mateo, CA) a telescoping catheter system single point of control outside the body, consisting an 8F Guide Catheter (Base Camp), 0.088‐in. inner diameter catheter‐extender (HiPoint 88), and ledge‐reducing delivery (Tenzing 8). In this study, we describe MS...
INTRODUCTION: Stent development has focused recently on low-profile, self-expandable stents compatible with 0.0165-inch microcatheters. The LVIS EVO is the second generation version of Low-Profile Visualized Intraluminal Support (LVIS) improved visibility as a result drawn filled tube (DFT) wires consisting an inner platinum wire and outer nitinol wire. underwent limited premarket release (PMR) in December 2023. METHODS: This multicenter retrospective observational study evaluating patients...
INTRODUCTION: Temporary artery occlusion is an important technique during the microsurgical repair of cerebral aneurysms. clip application and removal maneuvers commonly appear insignificant. Intraoperative diagnostic angiography (ioDCA) facilitates understanding temporary clipping sequelae. METHODS: Consecutive treatments performed between 01/2020 – 06/2023 were retrospectively reviewed. We included patients >18 years undergoing aneurysm immediate ioDCA prior to closure. Independent...
Socioeconomic status influences health outcomes, including cerebrovascular diseases. Patients from socioeconomically deprived areas may present with more severe conditions due to delayed access care. This study evaluates the association between neighborhood-level deprivation, measured by Area Deprivation Index (ADI), and treatment of ruptured intracranial aneurysms (RIAs) compared unruptured (UIAs) across multiple centers. retrospective cohort analyzed data 4517 patients treated for cerebral...
The Pipeline Embolization Device (PED; Medtronic) has been used off-label for the treatment of challenging posterior circulation aneurysms. Data on this modality are primarily limited to small retrospective single-center series.To assess safety and efficacy by establishing an international, multicenter collaboration.Consecutive aneurysms treated with PED from 2012 2019 across 11 neurovascular centers were retrospectively reviewed. Baseline demographics, aneurysm characteristics,...
The Woven EndoBridge (WEB) device is a novel intrasaccular flow disruptor tailored for bifurcation aneurysms. We aim to describe the degree of aneurysm occlusion at latest follow-up, and rate complications aneurysms treated with WEB stratified according rupture status.Our data were taken from WorldWideWeb Consortium, an international multicenter cohort including patients device. Aneurysms classified into two groups: ruptured unruptured. compared clinical radiologic outcomes both groups....
<h3>BACKGROUND AND PURPOSE:</h3> Current stroke care recommendations for patient selection mechanical thrombectomy in the extended time window demand advanced imaging to determine core volume and hypoperfusion mismatch, which may not be available at every center. We aimed outcomes patients selected solely on basis of noncontrast CT CTA early (<6-hour) (≥6-hour) windows. <h3>MATERIALS METHODS:</h3> Consecutive thrombectomies performed acute large-vessel occlusion ischemic (ICA, M1, M2)...
Flow diversion is a common endovascular treatment for cerebral aneurysms, but studies comparing different types of flow diverters are scarce.To perform propensity score matched cohort study the Pipeline Embolization Device (PED) and Redirection Intraluminal (FRED) posterior circulation aneurysms.Consecutive aneurysms treated at 25 neurovascular centers with either PED or FRED were collected. Propensity matching was used to control age, duration follow-up imaging, adjunctive coiling, aneurysm...
Background Temporary clipping (TC) is an essential adjunct in cerebral aneurysm (CA) surgery. Despite appearing insignificant to the surgeon under microscope, TC may cause parent vessel injury. Intraoperative diagnostic angiography (ioDCA) crucial for assessing occlusion and integrity. We aimed assess sequelae of evident on immediate ioDCA. Methods Elective CA clippings with ioDCA a hybrid operating room from January 2020 June 2023 were reviewed. Microsurgical angiographic assessments...
Complications from anterior approaches to the cervical spine are uncommon with normal anatomy. However, variant anatomy might predispose one an increased incidence of injury during such procedures. We hypothesized that left vertebral arteries arise aortic arch instead subclavian artery take a more medial path in their ascent making them susceptible iatrogenic injury. Fifty human adult cadavers were examined for having origin and these dissected along entire course. Additionally, two...
<b><i>Introduction:</i></b> White matter hyperintensity (WMH) burden is a critically important cerebrovascular phenotype related to the diagnosis and prognosis of acute ischemic stroke. The effect WMH on functional outcome in large vessel occlusion (LVO) stroke has only been sparsely assessed, direct LVO non-LVO comparisons are currently lacking. <b><i>Material Methods:</i></b> We reviewed patients admitted between 2009 2017 at healthcare...