Nico Münnich
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Clinical practice guidelines implementation
- Medical Imaging and Analysis
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Artery Disease Management
- Intracranial Aneurysms: Treatment and Complications
- RNA Research and Splicing
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
Witten/Herdecke University
2023-2025
Klinikum Dortmund
2022-2025
University Hospital Münster
2020
Philipps University of Marburg
2016
BackgroundLong-term data showing the benefits of endovascular thrombectomy for stroke with large infarct are scarce. The TENSION trial showed safety and efficacy in patients ischaemic at 90 days. We aimed to investigate 12 months who were enrolled trial.MethodsTENSION was an open-label, blinded endpoint, randomised done 40 hospitals across Europe one hospital Canada. included (aged ≥18 years) acute due vessel occlusion anterior circulation had a infarct, as indicated by Alberta Stroke...
In patients with large ischemic stroke, thrombectomy within 12 hours after onset was superior to best medical treatment in reducing 90-day functional disability irrespective of the collateral status on single-phase CT angiography images.
BACKGROUND: Recent randomized trials demonstrated the beneficial effect of endovascular therapy in patients with low Alberta Stroke Program Early Computed Tomography Score. Despite large follow-up infarct volumes, a significantly increased rate good functional outcomes was observed, challenging role volume as predictive imaging marker. This analysis evaluates extent to which effects thrombectomy on are explained by (1) and (2) early neurological status stroke METHODS: TENSION trial conducted...
Abstract Complete recanalization after a single retrieval maneuver is an interventional goal in acute ischemic stroke and independent factor for good clinical outcome. Anatomical biomarkers predicting clot removal difficulties have not been comprehensively analyzed await unused. We retrospectively evaluated 200 consecutive patients who suffered occlusion of the anterior circulation were treated with mechanical thrombectomy through balloon guide catheter (BGC). The primary objective was to...
Abstract Purpose Whether patients presenting with mild stroke (NIHSS at admission < 6) should be treated mechanical thrombectomy (MT) is the subject of an ongoing debate. This retrospective study based on large-scale clinical data aims to identify factors associated favorable outcome (FO) in stroke. Methods A total 761 enrolled between 1 January 2020 and 31 December Quality Registry German Society for Neuroradiology were analyzed. The FO was defined as stable or improved NIHSS discharge...
Various studies have identified prognostic factors for a favorable outcome of endovascular treatment in posterior circulation. We evaluated various machine learning algorithms their ability to classify between patients with (defined as 0-2 points on the modified Rankin scale [mRS]), unfavorable (mRS 3-6), poor 5-6), and nonpoor 0-4) outcomes at dismissal.We retrospectively analyzed data from 415 that were treated 2018 2021 multicentric DGNR registry. Five models (random forest, support...
Zielsetzung In der Behandlung von Patienten mit einem ischämischen Schlaganfall ist Zeit ein entscheidender Faktor. Primäres Ziel dieser Studie war Einfluss präklinischen und innerklinischen Logistik in Bezug auf die das klinische Outcome.