Georgios Tsivgoulis
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Atrial Fibrillation Management and Outcomes
- Intracranial Aneurysms: Treatment and Complications
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Long-Term Effects of COVID-19
- Cerebral Venous Sinus Thrombosis
- Multiple Sclerosis Research Studies
- Cardiovascular and Diving-Related Complications
- Antiplatelet Therapy and Cardiovascular Diseases
- Neurosurgical Procedures and Complications
- Peripheral Neuropathies and Disorders
- Peripheral Artery Disease Management
- Retinal and Optic Conditions
- Heart Rate Variability and Autonomic Control
- COVID-19 Clinical Research Studies
- Neurological Disorders and Treatments
- COVID-19 and healthcare impacts
- Cardiac Arrhythmias and Treatments
- Alzheimer's disease research and treatments
National and Kapodistrian University of Athens
2016-2025
University of Tennessee Health Science Center
2015-2024
Democritus University of Thrace
2012-2024
University Hospital of Alexandroupolis
2012-2024
University General Hospital Attikon
2015-2024
University of Calgary
2007-2024
King's College London
2024
Population Health Research Institute
2021-2024
St. Thomas Hospital
2024
McMaster University
2021-2024
Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist physicians in their clinical decisions regard intravenous were developed based on ESO standard operating procedure and followed Grading of Recommendations, Assessment, Development, Evaluation (GRADE) methodology. The working group identified relevant questions, performed...
To evaluate the relationship between systolic blood pressure (SBP) or diastolic (DBP) on admission and early late mortality in patients with acute stroke.Prospective study of hospitalized first-ever stroke over 8 years.Stroke unit medical wards a University hospital.A total 1121 admitted within 24 h from onset followed up for 12 months.Mortality at 1 months after relation to SBP DBP.Early ischaemic haemorrhagic DBP 'U-curve pattern'. After adjusting known outcome predictors, relative risk...
Transcranial Doppler (TCD) is a physiological ultrasound test with established safety and efficacy. Although imaging devices may be used to depict intracranial flow superimposed on structural visualization, the end-result provided by duplex or nonimaging TCD sampling variables through spectral waveform assessment.Clinical indications considered this multidisciplinary panel of experts as are: sickle cell disease, cerebral ischemia, detection right-to-left shunts (RLS), subarachnoid...
Background and Purpose— The best time for administering anticoagulation therapy in acute cardioembolic stroke remains unclear. This prospective cohort study of patients with atrial fibrillation, evaluated (1) the risk recurrent ischemic event severe bleeding; (2) factors recurrence (3) risks bleeding associated anticoagulant its starting after stroke. Methods— primary outcome this multicenter was composite stroke, transient attack, symptomatic systemic embolism, cerebral major extracranial...
<h3>Objective:</h3> There are limited data evaluating the effect of post mechanical thrombectomy (MT) blood pressure (BP) levels on early outcomes patients with large vessel occlusions (LVO). We sought to investigate association BP course following MT in LVO. <h3>Methods:</h3> Consecutive LVO treated during a 3-year period were evaluated. Hourly systolic (SBP) and diastolic (DBP) values recorded for 24 hours maximum SBP DBP identified. complete reperfusion stratified 3 groups based post-MT...
It is not known whether patients with atrial fibrillation (AF) ischemic stroke despite oral anticoagulant therapy are at increased risk for further recurrent strokes or how ongoing secondary prevention should be managed.
The coronavirus disease 2019 (COVID-19) pandemic has led to significant strain on front-line healthcare workers.In this multicentre study, we compared the psychological outcomes during COVID-19 in various countries Asia-Pacific region and identified factors associated with adverse outcomes.From 29 April 4 June 2020, study recruited workers from major institutions five region. A self-administrated survey that collected information prior medical conditions, presence of symptoms, scores...
The purpose of the European Stroke Organisation–Karolinska Update Conference is to provide updates on recent stroke therapy research and give an opportunity for participants discuss how these results may be implemented into clinical routine. meeting started 22 years ago as Karolinska Update, but since 2014 it a joint conference with Organisation. Importantly, provides platform discussion Organisation guidelines process recommendations committee specific topics. By this, adds direct influence...
The optimal blood pressure (BP) management in acute ischaemic stroke (AIS) and intracerebral haemorrhage (ICH) remains controversial. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist physicians their clinical decisions regarding BP stroke. were developed according the ESO standard operating procedure Grading of Recommendations, Assessment, Development, Evaluation (GRADE) methodology. working group identified relevant questions, performed...
To measure the global impact of COVID-19 pandemic on volumes IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at height (March 1 to June 30, 2020) compared with 2 control 4-month periods.We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, 457 centers. Diagnoses were identified by their ICD-10 codes or classifications in databases.There 91,373 admissions immediately before 80,894 during months, representing an...
<h3>Importance</h3> Thrombosis with thrombocytopenia syndrome (TTS) has been reported after vaccination the SARS-CoV-2 vaccines ChAdOx1 nCov-19 (Oxford–AstraZeneca) and Ad26.COV2.S (Janssen/Johnson & Johnson). <h3>Objective</h3> To describe clinical characteristics outcome of patients cerebral venous sinus thrombosis (CVST) without TTS. <h3>Design, Setting, Participants</h3> This cohort study used data from an international registry consecutive CVST within 28 days included between March...
Six randomized controlled clinical trials have assessed whether mechanical thrombectomy (MT) alone is non-inferior to intravenous thrombolysis (IVT) plus MT within 4.5 hours of symptom onset in patients with anterior circulation large vessel occlusion (LVO) ischemic stroke and no contraindication IVT. An expedited recommendation process was initiated by the European Stroke Organisation (ESO) conducted Society Minimally Invasive Neurological Therapy (ESMINT) according ESO standard operating...
Within the last year, four randomised-controlled clinical trials (RCTs) have been published comparing intravenous thrombolysis (IVT) with tenecteplase and alteplase in acute ischaemic stroke (AIS) patients a non-inferiority design for three of them. An expedited recommendation process was initiated by European Stroke Organisation (ESO) conducted according to ESO standard operating procedure based on Grading Recommendations, Assessment, Development Evaluations (GRADE) framework. We identified...
BackgroundPatients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect andexanet alfa, an agent that reverses the effects inhibitors, on volume expansion has not been well studied.MethodsWe randomly assigned, in 1:1 ratio, patients had taken within 15 hours before having to receive or usual care. primary end point was hemostatic efficacy, defined by 35% less at 12 after baseline, increase score National Institutes Health...
Six randomized controlled clinical trials have assessed whether mechanical thrombectomy (MT) alone is non-inferior to intravenous thrombolysis (IVT) plus MT within 4.5 hours of symptom onset in patients with anterior circulation large vessel occlusion (LVO) ischaemic stroke and no contraindication IVT. An expedited recommendation process was initiated by the European Stroke Organisation (ESO) conducted Society Minimally Invasive Neurological Therapy (ESMINT) according ESO standard operating...