A5004130675- Long-Term Effects of COVID-19
- Peripheral Neuropathies and Disorders
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Acute Ischemic Stroke Management
- Epilepsy research and treatment
- Retinal and Optic Conditions
- COVID-19 Clinical Research Studies
- Autoimmune Neurological Disorders and Treatments
- Spondyloarthritis Studies and Treatments
- Lymphadenopathy Diagnosis and Analysis
- Pneumocystis jirovecii pneumonia detection and treatment
- COVID-19 Pandemic Impacts
- Infection Control and Ventilation
- Immunodeficiency and Autoimmune Disorders
- Infectious Encephalopathies and Encephalitis
- Healthcare professionals’ stress and burnout
- Neuroscience and Neuropharmacology Research
- Climate Change and Health Impacts
- Heparin-Induced Thrombocytopenia and Thrombosis
- Optimism, Hope, and Well-being
- Dermatological and COVID-19 studies
- Soft tissue tumors and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
National University Hospital
2019-2025
National University Health System
2016-2025
National University of Singapore
2003-2025
Seoul National University Hospital
2025
Sunway University
2025
University Health System
2021
Rush University
2020
Sleep Research Society
2020
Singapore General Hospital
2019
Ministry of Health
2016
Letters6 April 2020Psychological Impact of the COVID-19 Pandemic on Health Care Workers in SingaporeFREEBenjamin Y.Q. Tan, MD*, Nicholas W.S. Chew, Grace K.H. Lee, MD, Mingxue Jing, Yihui Goh, Leonard L.L. Yeo, Ka Zhang, Howe-Keat Chin, Aftab Ahmad, Faheem Ahmed Khan, Ganesh Napolean Shanmugam, MBBCh, Bernard P.L. Chan, Sibi Sunny, Bharatendu Chandra, Jonathan J.Y. Ong, Prakash R. Paliwal, Lily Y.H. Wong, BN, Renarebecca Sagayanathan, BSc, Jin Tao Chen, Alison Ying Ng, Dip, Hock Luen Teoh,...
Background Coronavirus disease 2019 (COVID‐19) is an emerging infectious of pandemic proportions. Healthcare workers in Singapore working high‐risk areas were mandated to wear personal protective equipment (PPE) such as N95 face mask and eyewear while attending patients. Objectives We sought determine the risk factors associated with development de novo PPE‐associated headaches well perceived impact these on their health work performance. The COVID‐19 pre‐existing headache disorders was also...
Coronavirus disease 2019 (COVID-19) has been associated with various neurologic manifestations, including anosmia, acute ischemic stroke, Guillain-Barré syndrome, and encephalopathy.c During the COVID-19 pandemic, physicians seeing patients these manifestations should consider as a differential diagnosis to prevent diagnostic delays further transmission of disease.c Cranial nerve involvement could potentially be COVID-19. Oy-sters cWhen patient presents isolated facial palsy, careful...
Background and aimCOVID-19 pandemic has resulted in an unprecedented increased usage of Personal protective equipment (PPE) by healthcare-workers. PPE causes headache majority users. We evaluated changes cerebral hemodynamics among healthcare-workers using PPE.MethodsFrontline donning at our tertiary center were included. Demographics, co-morbidities blood-pressure recorded. Transcranial Doppler (TCD) monitoring middle artery was performed with 2-MHz probe. Mean flow velocity (MFV)...
To describe the spectrum of COVID-19 neurology in Singapore.
This case series reports three patients initially managed for presumed infectious meningoencephalitis, who were ultimately diagnosed with myelin oligodendrocyte glycoprotein associated disease (MOGAD). Their clinical presentations strikingly similar to those of acute which posed a challenge the initial diagnostic process. Notably, despite absence typical radiological changes MOGAD, such as cerebral cortical encephalitis, these exhibited focal neurological and electroencephalographic changes....
Cytokine profiling before immunotherapy is increasingly prevalent in febrile infection-related epilepsy syndrome (FIRES). In this case, an 18-year-old man presented with first-onset seizure after a nonspecific illness. He developed super-refractory status epilepticus requiring multiple antiseizure medications and general anesthetic infusions. was treated pulsed methylprednisolone plasma exchange started on ketogenic diet. Contrast-enhanced MRI brain revealed postictal changes. EEG findings...
ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of with unclear etiology. The identification relevant early biomarkers in cNORSE important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes cNORSE. Methods CSF samples were obtained within 7 days NORSE from an adult cohort national referral center South Korea. Nineteen patients studied: 9 male (47.4%) median age...
An intelligent agent-based framework that supports fourth-party logistics (4PL) operations on the Web is proposed. In our system, customers specify job requests over dynamically. e-marketplace allows third-party (3PL) agents to bid for customers' requests. The intelligence lies in optimally deciding which agents' bids should be satisfied based a set of predetermined factors (pricing, preferences and fairness). We model underlying brokering problem as packing (SPP), an NP-hard optimization...
The COVID-19 pandemic has had an unprecedented impact on healthcare systems globally, giving rise to significant morbidity and mortality. Vaccination been widely regarded as the most important strategy contain pandemic. Whilst local side-effects of BNT-162b2 (Pfizer-BioNTech) vaccine are well known, concern emerged due sporadic reports immune-mediated adverse effects (Cines Bussel, 2021; Rela et al., 2021). As August 19, 2021, 4.54 million individuals received vaccines in Singapore (Oxford...
Abstract Aim Axial spondyloarthritis (axSpA) affects patients in the prime of their economic productivity. We aim to identify factors associated with poor work productivity axSpA Singapore. Methods A cross‐sectional study was performed two tertiary centers Consecutive adult ≥21 years fulfilling Assessment Spondyloarthritis International Society (ASAS) 2009 criteria for were recruited. Data on social demographics, clinical, treatment modalities and patient‐reported outcome measures (PROMs)...
Summary Background Individuals who suffered a neurological adverse event after the Coronavirus disease (COVID-19) vaccine could hesitate and defer reimmunization. Aim We examine risk of recurrence following reimmunization among patients developed first dose COVID-19 mRNA vaccine. Design Observational study. Methods an adjudicated (based on Brighton Collaboration criteria) within 6 weeks requiring hospitalization were enrolled into multicenter national registry in Singapore. Neurological...
Background: The Coronavirus disease 2019 (COVID-19) pandemic is rapidly evolving and affecting healthcare systems across the world. Singapore has escalated its alert level to Disease Outbreak Response System Condition (DORSCON) Orange, signifying severe with community spread. Objectives: We aimed study overall volume of AIS cases delivery hyperacute stroke services during DORSCON Orange. Methods: This was a single-centre, observational cohort performed at comprehensive centre responsible for...
Polymyxin-induced neuromuscular blockade is a rare but potentially fatal condition, with majority of cases that were reported between 1962 and 1973. We describe patient who developed hypercapnic respiratory failure after initiation polymyxin for multi-drug resistant Escherichia Coli bacteremia, due to polymyxin-induced dysfunction. After cessation polymyxin, he regained full strength, had complete resolution ptosis, was successfully extubated. In light the renewed use in this era...