Francesca Guideri
A5075801309- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Cerebrovascular and Carotid Artery Diseases
- Genetics and Neurodevelopmental Disorders
- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Disease Prevention
- Cardiac Arrhythmias and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Autism Spectrum Disorder Research
- Blood properties and coagulation
- Transplantation: Methods and Outcomes
- Cardiac Ischemia and Reperfusion
- Cerebrovascular and genetic disorders
- Cardiovascular Function and Risk Factors
- Child Nutrition and Feeding Issues
- Heart Rate Variability and Autonomic Control
- Folate and B Vitamins Research
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- RNA regulation and disease
- Monoclonal and Polyclonal Antibodies Research
- Family and Disability Support Research
- Viral Infections and Immunology Research
University of Siena
2005-2024
Azienda Ospedaliera Universitaria Senese
2015-2024
Stroke Association
2024
Jazz Pharmaceuticals (Italy)
2020
Ospedale Santa Maria alle Scotte
2009-2018
St. Anne's University Hospital Brno
2017
University Hospital of Alexandroupolis
2017
Democritus University of Thrace
2017
University General Hospital Attikon
2017
National and Kapodistrian University of Athens
2017
Background and Purpose— The best time for administering anticoagulation therapy in acute cardioembolic stroke remains unclear. This prospective cohort study of patients with atrial fibrillation, evaluated (1) the risk recurrent ischemic event severe bleeding; (2) factors recurrence (3) risks bleeding associated anticoagulant its starting after stroke. Methods— primary outcome this multicenter was composite stroke, transient attack, symptomatic systemic embolism, cerebral major extracranial...
Background The optimal timing to administer non–vitamin K oral anticoagulants ( NOAC s) in patients with acute ischemic stroke and atrial fibrillation is unclear. This prospective observational multicenter study evaluated the rates of early recurrence major bleeding (within 90 days) their who received s for secondary prevention. Methods Results Recurrence was defined as composite stroke, transient attack, symptomatic systemic embolism, cerebral extracranial bleeding. For analysis, 1127 were...
Background and Purpose- Despite treatment with oral anticoagulants, patients nonvalvular atrial fibrillation (AF) may experience ischemic cerebrovascular events. The aims of this case-control study in AF were to identify the pathogenesis risk factors for events occurring during non-vitamin K antagonist anticoagulants (NOACs) therapy stroke prevention. Methods- Cases consecutive who had acute NOAC treatment. Controls did not have NOACs Results- Overall, 713 cases (641 strokes 72 transient...
Background In patients with acute ischemic stroke and atrial fibrillation, early anticoagulation prevents recurrence but the risk of hemorrhagic transformation ( HT ). The aims this study were to evaluate in consecutive fibrillation (1) incidence HT, (2) time initiation , (3) association recurrences, (4) clinical outcome at 90 days. Methods Results was diagnosed by a second brain computed tomographic scan performed 24 72 hours after onset. recurrences as well mortality or disability...
Abstract Objective Newborns of mothers positive for anti‐Ro/SSA autoantibodies may develop a series electrocardiographic (EKG) disturbances. Prolongation the corrected QT (QTc) interval was recently reported in significant proportion children with maternally acquired antibodies, concomitant disappearance EKG abnormalities and maternal during first year, suggesting direct, reversible electrophysiologic effect antibodies on ventricular repolarization. On this basis, we investigated whether...
The modified Rankin Scale (mRS) and the Barthel Index (BI) are most common clinimetrical instruments for measuring disability after stroke. This study investigated relationship between BI mRS at multiple time points BI, which is a widely used instrument longitudinal follow-up post-stroke, was as reference to determine effect of on sensitivity in differentiating functional recovery.Ninety-two patients with first stroke hemispheric brain lesion were evaluated using 10 days, 3 6 months....
Incidence of sudden death in Rett syndrome is greater than that the general population and cardiac electrical instability a prime suspect cause. Our study shows girls with had significantly lower heart rate variability (marker autonomic disarray) longer corrected QT intervals compared an age-matched group healthy girls. These abnormalities increased advancing stages syndrome. findings suggest possible role dysfunction associated
This study was designed to derive and validate a score predict early ischemic events major bleedings after an acute stroke in patients with atrial fibrillation.The derivation cohort consisted of 854 fibrillation included prospective series between January 2012 March 2014. Older age (hazard ratio 1.06 for each additional year; 95% confidence interval, 1.00-1.11) severe enlargement ratio, 2.05; 1.08-2.87) were predictors outcome (stroke, transient attack, systemic embolism) at 90 days from...
Background and Purpose— Bridging therapy with low-molecular-weight heparin reportedly leads to a worse outcome for acute cardioembolic stroke patients because of higher incidence intracerebral bleeding. However, this practice is common in clinical settings. This observational study aimed compare (1) the profiles receiving not bridging therapy, (2) overall group outcomes, (3) outcomes according type anticoagulant prescribed. Methods— We analyzed data from prospective RAF RAF-NOACs studies....
Incidence of sudden death in Rett syndrome is greater than that the general population, and cardiac electrical instability a prime suspect cause. The objective present study was evaluation heart rate variability, marker autonomic activity, females affected by classic atypical variants for possible explanation higher risk observed these subjects. Our showed girls with had significantly lower variability longer corrected QT intervals age-matched healthy girls. Reduction progresses age clinical...
Intracerebral hemorrhage (ICH) accounts for approximately 10% of stroke cases. Hypertension may play a role in the pathogenesis ICH that occurs basal ganglia, thalamus, pons, and cerebellum, but not lobar ICH. contributes to decreased elasticity arteries, thereby increasing likelihood rupture response acute elevation intravascular pressure. This study aimed evaluate arterial stiffness (using index [ASI]) patients with deep (putaminal thalamic) comparison ICH.We enrolled 64 (mean±SD age:...